thesis projects

   
MEDICA MEDICA
Metabolic Diseases and Cancer
 
Redox homeostasis in metabolic liver disease
Student: Aniket Nikam; Supervisor: Peter Abuja
 
The effect of diabetes-associated high insulin and IGF2 on the placental vasculature
Student: Luciana Lassance Gomes; Supervisor: Gernot Desoye
 
Effects of vitamins C and E on human trophoblast
Student: Julia Froehlich; Supervisor: Gernot Desoye
 
The impact of endothelial lipase (EL)-generated lipid metabolites on the endothelium-dependent vascular tone
Student: Lada Brkic; Supervisor: Sasa Frank
 
The impact of endothelial lipase in pulmonary hypertension
Student: Slaven Crnkovic; Supervisors: Sasa Frank and Andrea Olschewski
 
The role of peroxisome and lipotoxicity in the development of tumor-associated cachexia
Student: Suman Kumar Das; Supervisor: Gerald Hoefler
 
Metabolic (cardio)myopathy
Student: Tamilarasan Kuppusamy Palaniappan; Supervisor: Gerald Hoefler
 
Molecular markers to predict clinical outcome and therapy response in stage II colon cancer
Student: Upeka Senanayake; Supervisors: Gerald Hoefler and Michael Speicher
 
Molecular mechanisms of cachexia and lipotoxicity in cirrhotic cardiomyopathy
Student: Pooja Kumari; Supervisors: Gerald Hoefler and Michael Trauner
 
Human trophoblast: A model for controlled invasion
Student: Gerit Moser; Supervisor: Berthold Huppertz
 
Preeclampsia: 1st trimester markers to predict the syndrome
Student: Kristina Orendi; Supervisor: Berthold Huppertz
 
Endothelial differentiation potential of stromal cells derived from human placenta
Student: Julia Koenig; Supervisor: Berthold Huppertz
 
Single cell analysis of circulating tumor cells isolated by size filtration
Student: Amin El-Heliebi; Supervisor: Berthold Huppertz
 
Metabolism and transcriptional regulation of lipoprotein (a)
Student: Indumathi Chennamsetty; Supervisor: Gerhard Kostner
 
Characterization of novel tumor suppressing genes in hepatocellular and colorectal carcinoma
Student: Andrija Matak; Supervisors: Gerhard Kostner and Kurt Zatloukal
 
The influence of micro-RNA's on lipid and lipoprotein metabolism
Student: Manjula Vinod; Supervisor: Gerhard Kostner
 
Functional characterization of new LXR-target proteins in cholesterol absorption
Student: Thomas Pfeifer; Supervisor: Sanja Levak-Frank
 
Transcriptional control of intestinal cholesterol homeostasis
Student: Jay Patankar; Supervisor: Sanja Levak-Frank
 
The role of ATGL in regulation of lipid metabolism in the small intestine
Student: Sascha Obrowsky; Supervisor: Sanja Levak-Frank
 
Impact of lipases on brain lipid homeostasis
Student: Karoline Etschmaier; Supervisor: Ute Panzenboeck
 
Blood-brain barrier lipoproteins and their roles in neurodegeneration
Student: Cornelia Schweinzer; Supervisor: Ute Panzenboeck
 
Regulation of HDl mediated sterol transfer across the placenta
Student: Monika Scholler; Supervisors: Ute Panzenboeck and Gernot Desoye
 
Anti-proliferative and apoptosis-inducing effects of HCMV US28 on melanoma cell lines
Student: Shripad Prakash Joshi; Supervisor: Helmut Schaider
 
Epithelial-mesenchymal transition in melanomagenesis
Student: Dinoop Menon; Supervisor: Helmut Schaider
 
Mechanisms resulting in aneuploidy during aging
Student: Anna Obenauf; Supervisor: Michael Speicher
 
Chromosomal instability in aging and cancer
Student: Kristina Aleksic; Supervisor: Michael Speicher
 
Characterisation of genetic changes in medullary thyroid carcinoma for improvement of both diagnosis and treatment
Student: Karin Flicker; Supervisor: Michael Speicher
 
Phenotypic and molceular analysis of potential metastatic precursor cells in clinical samples and analysis of serum DNA
Student: Eva Maria Hoffmann; Supervisor: Michael Speicher
 
The role of hepatic phospholipid export pump (Multidrug resistance protein Mdr2/Abcb4) in the pathogenesis of metabolic, cholestatic and neoplastic liver disease
Student: Emina Halilbasic; Supervisor: Michael Trauner
 
Nuclear receptor regulation of hepatic phospholipid export pump (Multidrug resistance protein Mdr2/Abcb4) in the pathogenesis of metabolic, cholestatic and neoplastic liver disease
Student: Anna Baghdasaryan; Supervisor: Michael Trauner
 
The role of hepatic bile acid pump and bile acid-activated nuclear receptors in the control of hepatic lipid metabolism and defense against lipotoxicity
Student: Claudia Fuchs; Supervisor: Michael Trauner
 
Role of ligand-activated nuclear receptors and hepatobiliary transporters for progression of inflammation and fibrosis in the pathogenesis of PSC
Student: Marion Pollheimer; Supervisor: Michael Trauner
 
Role of hepatic triglyceride lipases in fatty liver disease
Student: Jeannine Schneider; Supervisor: Michael Trauner
 
Molecular pathogenesis of chronic metabolic and degenerative liver disesase
Student: Vineet Mahajan; Supervisors: Kurt Zatloukal, Helmut Denk and Peter Abuja
 
 
MOLIN

MOLIN
Mol
ecular Inflammation

 
Mitochondrial Ca2+-regulation in endothelial cells
Student: Shamim Naghdi; Supervisor: Wolfgang Graier
 
Contribution of mitochondria to cancer - Potential targets for therapeutic intervention?
Student: Muhammad Jadoon Khan; Supervisor: Wolfgang Graier
 
Molecular mechanisms of lipotoxicity in endothelial cells
Student: Muhammad Rizwan Alam; Supervisor: Wolfgang Graier
 
Signaling and function of endocannabinoid-sensitive receptors in endothelial cells
Student: Alexandra Barbulescu; Supervisor: Wolfgang Graier
 
Pharmacological targeting of endothelium-leukocyte interaction in allergic inflammation
Student: Viktoria Konya; Supervisor: Akos Heinemann
 
Studying cell death in mice which lack or overexpress intracellular lipases
Student: Elma Aflaki; Supervisor: Dagmar Kratky
 
Investigating foam cell formation and atherosclerosis susceptibility in mice that lack or overexpress intracellular lipases
Student: Prakash Chandak; Supervisor: Dagmar Kratky
 
Identification and characterization fo proteins in foam cell-derived lipid droplets
Student: Prakash Doddapattar; Supervisor: Dagmar Kratky
 
Expression and regulation of HO-1 by HOCl-modified (lipo)proteins
Student: Christine Rossmann; Supervisor: Ernst Malle
 
Identification of endothelial receptors for carbamylated LDL
Student: Michael Holzer; Supervisor: Gunther Marsche
 
Is uremic high-density lipoprotein dysfunctional?
Student: Veronika Binder; Supervisor: Gunther Marsche
 
Response of endothelial cells of different vascular beds to inflammatory stimulation
Student: Dalia El-Gamal; Supervisors: Gunther Marsche & Akos Heinemann
 
Impact of TASK-1 in human pulmonary artery smooth muscle cells
Student: Nagaraj Chandran; Supervisor: Andrea Olschewski
 
Characterization of endothelial cells involved in chronic thromboembolic pulmonary hypertension
Student: Diana Zabini; Supervisor: Andrea Olschewski
 
Mechanisms of hypoxia-induced chemoresistance - the role of death receptors, IAP family member survivin and K+ channels
Student: Christoph Wohlkoenig; Supervisor: Horst Olschewski
 
Basic aspects of neuroinflammation
Student: Arijit Ghosh; Supervisor: Thomas Pieber
 
Polycystic ovary syndrome - challenge between steroid and glucose pathways
Student: Uyen Do Phuong Lam; Supervisor: Thomas Pieber
 
Subcellular ion homeostasis and gene expression in heart failure
Student: Senka Ljubojevic; Supervisor: Burkert Pieske
 
Molecular mechanisms of arrhythmias in heart failure
Student: Michael Sacherer; Supervisor: Burkert Pieske
 
Molecular mechanisms of neurogenic hyperresponsiveness in bronchial asthma
Student: Sonia Philipose; Supervisor: Rufina Schuligoi
 
Modified lipids as regulators of microglia function
Student: Christoph Nusshold; Supervisor: Wolfgang Sattler
 
Myeloperoxidase-mediated lipotoxicity in the central nervous system
Students: Sabine Waltl and Andreas Uellen; Supervisor: Wolfgang Sattler
 
Four-dimensional molecular imaging of human stem cells
Student: Andreas Reinisch; Supervisor: Dirk Strunk
 
A systems biology approach towards novel regenerative stem cell therapy strategies
Student: Rokhsareh Rohban; Supervisor: Dirk Strunk
 
Oxygen sensing of adult stem cells
Student: Nicole Hofmann; Supervisor: Dirk Strunk
 
Dynamic neuroimmunological regulation of stem cell biology and immune cell ontology
Student: Anna Ortner; Supervisor: Dirk Strunk
 
Mutation screening, molecular characterization and functional analysis of the Four and a Half LIM domains (FLH1) gene
Student: Ivana Poparic; Supervisor: Klaus Wagner
 
Characterization of the novel cannabinoid receptor GPR55
Student: Nariman Balenga; Supervisor: Maria Waldhoer
 
Human cytomegalovirus-encoded GPCRs and their impact on host cell biology
Students: Elisabeth Moser and Pia Tschische; Supervisor: Maria Waldhoer
 
Signaling and trafficking properties of oligomerized PGD2 receptors
Student: Miriam Sedej; Supervisors: Maria Waldhoer and Akos Heinemann
 
Regulation of the novel endocannabinoid receptor GPR55 by the G protein coupled receptor associated sorting protein GASP
Student: Julia Kargl; Supervisor: Maria Waldhoer
 
Transcriptional regulation of cyclooxygenase-2 expression in human osteosarcoma
Student: Kerstin Kitz; Supervisor: Werner Windischhofer
 
Platelet-activating factor (PAF) signaling in photo(chemo)therapy-responsive diseases
Student: Tej Pratap Singh; Supervisor: Peter Wolf