Ruth Birner-Gruenberger
Projects within the DK-MCD
| Functional proteomics and metabolomics for the study of cancer metabolism |
Katarina Fritz graduated |
| Fatty acid species-dependent hepatic cellular lipotoxicity |
Juergen Gindlhuber graduated |
| Lipid hydrolysis in cancer metabolism |
Sophie Honeder graduated |
Regulation of intracellular lipid storage and mobilization |
Anita Sahu-Osen graduated |
Lipid storage and mobilisation in liver disease |
Maximilan Schinagl graduated |
Role of adipose triglyceride lipase (ATGL) in cancer metabolism |
Tamara Tomin graduated |
Discovery of polyesterases using proteomics |
Pål William Wallace graduated |
Research interest
Our group investigates lipid metabolism using proteomics and metabolomics for the study of lipolysis and the interplay of metabolic pathways and organelles in regulation of fatty acid and energy homeostasis in health, cancer and lipid-associated diseases. We develop tools and workflows to enable discovery and analysis of enzymes, metabolites, improve data analysis, and assess high-resolution mass spectrometer performance.
Our DK-MCD-students analyze the molecular (phospho)proteomic, metabolic, and lipid signaling networks related to lipolysis and fatty acid metabolism to understand the (dys)regulation of lipid metabolism in health, cancer, and lipid-associated diseases.
Curriculum vitae
| 1991 - 1998 | Studies of Chemistry and Biochemistry at the Graz University of Technology | |
| 1996 - 1997 | Master Thesis at the Royal Melbourne Institute of Technology (RMIT), Melbourne, Australia | |
| 1997 | Equivalent of a first class Bachelor Honours degree (high distinction), Applied Science, Royal Melbourne Institute of Technology (RMIT), Melbourne, Australia | |
| 1998 | Dipl.-Ing. (MSc, high distinction), Chemistry, Graz University of Technology | |
| 1998 - 2002 | PhD Thesis at the Department of Biochemistry, Graz University of Technology | |
| 1998 | EMBO practical course: Membrane lipids: Organization, dynamics and interaction with proteins, Utrecht, The Netherlands | |
| 1999 | FEBS advanced course: Yeast Lipids: Metabolism and intracellular transport, Utrecht, The Netherlands | |
| 2001 - 2003 | Assistant Professor at the Department of Biochemistry, Graz University of Technology | |
| 2002 | Dr. techn. (PhD, high distinction), Chemistry, Graz University of Technology | |
| 2003 | Courses: Separation sciences and Mass spectrometry for proteomics, Geneva proteomics centre, Switzerland | |
| 2003 - 2007 | Postdoctoral fellow at the Institute of Biochemistry, Graz University of Technology | |
| 2007 | Habilitation in Biochemistry, Institute of Molecular Biology and Biochemistry, Medical University of Graz | |
| 2007 - 2011 | Director, Mass Spectrometry Core Facility, Center of Medical Research (ZMF), Medical University of Graz | |
| 2009 - | Key Researcher, Austrian Center of Biotechnology (ACIB) | |
| 2010 | Erasmus staff training in quantitative phosphoproteomics, The Netherlands Proteomics Centre, University of Utrecht, The Netherlands | |
| 2011 - | Associate Professor, Institute of Pathology, Medical University of Graz | |
| 2012 | Research training in protein arrays, Technology Research Group, Babraham Institute, Cambridge, UK | |
| 2013 - | Head of Omics Center Graz, BioTechMed-Graz, Austria | |
| 2015 - | President Austrian Proteomics and Metabolomics Association (AuPA) | |
| 2015 | Computational Proteomics summer school, Max-Plank Institute Martinsried, Germany | |
| 2016 - | Board Member Deutsche Gesellschaft für Fettwissenschaft (DGF) | |
| 2016 | Visiting Professor, Institute of Molecular Systems Biology and Institute of Health Sciences and Technologies, ETH Zürich, Switzerland | |
| 2017 | Computational Proteomics winter school, Semmering, Austria | |
| 2017 | Visiting Professor, Institute of Nutrition and Toxicology, UC Berkeley, California | |
| 2017 | DIA (Data Independent Acquisition) course, ETH Zürich, Switzerland | |
| 2017 - | General Council Member Human Proteome Organisation (HUPO) | |
| 2018 - | Head of the Bruker Center of Excellence for Life Science Mass Spectrometry | |
| 2018 | Visiting Professor, University of Witwatersrand, Johannesburg, South Africa | |
| 2019 - | Full Professor for Bioanalytics, Vienna University of Technology, Austria | |