Center for Microbiome Research | Zentrum für Mikrobiomforschung

Medizinische Universität Graz

Center for Microbiome Research
Projects

Microbiome and health

⇒ "Investigation of the gut microbial profiles of the Fulanis and elderly diabetic patients in relation to the urban and healthy control"

Involved partners: Ayorinde Afolayan, Funmilola Ayeni, Christoph Högenauer, Christine Moissl-Eichinger, Gregor Gorkiewicz, Lawrence Adebusoye, Eniola Cadmus

Financial support: ÖAD (Austrian Agency for International Cooperation in Education and Research)

 


 ⇒ "The Correspondence of the Nasal Microbiome and Olfactory Function"

Involved partners: Kaisa Koskinen, Johanna Reichert (Karl Franzens University Graz), Stefan Hoier, Christine Moissl-Eichinger, Veronika Schöpf (Karl Franzens University Graz, PI)

Financial support: BioTechMed

 

"Mikrobielle Lebend-Tot Analyse in Stuhlproben"

Involved partners: Alexandra Perras (PI), Christine Moissl-Eichinger

Financial support: Stadt Graz

  

"How probiotics influence emotions in healthy human volunteers: neuroimaging perspectives"

Involved partners: Deepika Bagga (Karl Franzens University Graz, PI), Veronika Schöpf (Karl Franzens University Graz, PI), Kaisa Koskinen, Christine Moissl-Eichinger

Financial support: BioTechMed

 

"Transfer of strictly anaerobic microorganisms from mother to child (TRAMIC)"

Involved partners: Manuela Pausan, Evelyn Jantscher-Krenn, Vassiliki Kolovetsiou-Kreiner, Eva Christine Weiss, Christine Moissl-Eichinger, et al.

Financial support: BioTechMed, MolMed

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"Interplay between herbal medicine and intestinal bacteria: Metabolism of plant constituents and their impact on microbiome composition"

Involved partners: Eva-Maria Pferschy-Wenzig (Karl Franzens University Graz), Kaisa Koskinen, Christine Moissl-Eichinger, Rudolf Bauer (Karl Franzens University Graz)

 

 

Microbiome and brain

⇒ "Psychopharmacology of visceral immune activation"

Involved partners: Peter Holzer (PI), Aitak Farzi, Florian Reichmann, Esther E. Fröhlich, Raphaela Mayerhofer, Geraldine Zenz, Angela Jancic, Ahmed Hassan, Piyush Jain, Barbara Kofler (Salzburg), Herbert Herzog (Sydney, Australia)

Financial support: Austrian Science Fund (FWF)

 

⇒ "Identification of the mechanisms by which the intestinal microbiota and key bacteria modulate the gut-brain axis thereby influencing brain function"

Involved partners: Peter Holzer (PI), Ahmed Hassan, Aitak Farzi, Florian Reichmann, Karl Kashofer, Gregor Gorkiewicz, Nathalie Delzenne (Brussels, Belgium); Dirk Haller (Munich, Germany); Sandrine P. Claus (Reading, UK); Yolanda Sanz (Valencia, Spain); Herbert Herzog (Sydney, Australia)

Financial support: European Commission (EC)

 

⇒ "Biomarkers for probiotic effects on microbiome-gut-brain axis"

Involved partners: Peter Holzer (PI), Angela Jacan, Aitak Farzi, Esther E. Fröhlich, Geraldine Zenz, Karl Kashofer, Gregor Gorkiewicz, Nathalie Bordag, Institut Allergosan, QPS Austria

Financial support: Austrian Research Promotion Agency (FFG), within CBmed K1 competence center

 

⇒ "Impact of viral and bacterial immune activation on brain function"

Involved partners: Peter Holzer (PI), Geraldine Zenz, Florian Reichmann, Aitak Farzi, Esther E. Fröhlich, Barbara Kofler (Salzburg), Herbert Herzog (Sydney, Australia)

Financial support: Austrian Science Fund (FWF), within DK "Molecular Fundamentals of Inflamation"

Microbiome and probiotics

"Probiotics in liver cirrhosis" 

Involved partners: A. Horvath, B. Leber, R. Rainer, C. Moissl-Eichinger, M. Durdevic, I. Klymiuk. V. Stadlbauer

 

⇒ "Proton pump inhibitors in liver cirrhosis"

Involved partners: A. Horvath, R. Rainer, B. Leber, C. Moissl-Eichinger, M. Durdevic, I. Klymiuk, A. Groselj-Strele, V. Stadlbauer

 

⇒ "Probiotics in diabesity"

Involved partners: A. Horvath, B. Leber, M. Durdevic, I. Klymiuk. V. Stadlbauer

 

⇒ "Probiotics in early sepsis"

Involved partners: B. Leber, A. Horvath, M. Durdevic, I. Klymiuk. V. Stadlbauer

 

⇒ "Sarcopenia and microbiome in cirrhosis" 

Involved partners: J. Haberl, A. Horvath, B. Leber, M. Durdevic, I. Klymiuk. V. Stadlbauer

 

⇒ "Microbiome in end stage renal failure"

Involved partners: A. Horvath, B. Leber, M. Durdevic, I. Klymiuk. V. Stadlbauer

 

⇒ "Microbiome in secondary sclerosing cholangitis"

Involved partners: A. Blesl, A. Horvath, B. Leber, C. Moissl-Eichinger, M. Durdevic, I. Klymiuk. V. Stadlbauer

 

⇒ "Microbiome in dementia"

Involved partners: A. Horvath, B. Leber, C. Moissl-Eichinger, M. Durdevic, I. Klymiuk. V. Stadlbauer

 

 

Microbiome and fecal microbiota transplantation

⇒ “Fecal microbiota transplantation for therapy refractory ulcerative colitis”

Involved partners: Christoph Högenauer (PI), Patrizia Kump, Philipp Wurm, Gregor Gorkiewicz
Financial support: Seres Therapeutics


⇒ “Study investigating if specific fecal microbiota alterations can predict a refractory disease course to standard steroid therapy in patients with active ulcerative colitis”

Involved partners: Christoph Högenauer (PI), Bettina Halwachs, Gregor Gorkiewicz,Austrian IBD Study Group (ATISG)
Financial support: Austrian Society for Gastroenterology and Hepatology (ÖGGH)

 

⇒ “Microbiota alterations in critical ill patients”

Involved partners: Christoph Högenauer (PI), Robert Krause (PI),Bettina Halwachs, Gregor Gorkiewicz, Christine Moissl-Eichinger, Kaisa Koskinen
Financial support: CBMed

 

⇒ “Colonic bacterial dysbiosis as a cause of infant proctocolitis - A prospective controlled cohort study”

Involved partners: Karl Martin Hoffmann (PI), Christoph Högenauer, Robert Krause, Eva Leitner, Gregor Gorkiewicz
Financial support: FWF

 

⇒ “Fecal microbiota transplantation in therapy refractory graft versus host disease”

Involved partners: Christoph Högenauer (PI), Peter Neumeister (PI), Walter Spindelböck, Hildegard Greinix, Gregor Gorkiewicz

 

⇒ “Randomized controlled study investigating the efficacy of fecal microbiota transplantation in irritable bowel syndrome (IBS)”

Involved partners: Patrizia Kump (PI), Christoph Högenauer, Gregor Gorkiewicz

 

⇒ “Stability of the intestinal microbiota in inflammatory bowel disease and irritable bowel syndrome under the influence of an osmotic laxative”

Involved partners: Christoph Högenauer (PI), Andreas Blesl, Patrizia Kump (PI), Gregor Gorkiewicz

 

Completed projects:

⇒ "The salivary microbiome mirrors tumor stage and pre-conditions of patients with oropharyngeal squamous cell carcinoma" Involved partners: Axel Wolf, Christine Moissl-Eichinger, Alexandra Perras, Kaisa Koskinen, Peter V. Tomazic, Dietmar Thurnher (PI) Publication is available here.

Microbiome and the (clinical) environment

 

"Mikrobielle Übertragungswege in Intensivstationen"

Involved partners: Kaisa Koskinen (PI), Christine Moissl-Eichinger

Financial support: Stadt Graz

 

"Hospital microbiome project: Connecting pathogenic infection risk, healthy microbes and environmental biodiversity"

Involved partners: Kaisa Koskinen (PI), Christine Moissl-Eichinger

Financial support: Medical University Graz

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Microbiome in extreme and space

"ARBEX: ARchaeal and bacterial extremophiles on board the International Space Station."

Involved partners: Christine Moissl-Eichinger (PI), Maximilian Mora, Lisa Wink, Alexandra Perras, R. Krause, Tatjana Alekhova (Moscow State University), Charles Cockell (Open University, UK), Stefan Leuko (DLR Cologne), Petra Rettberg (DLR Cologne), Kasthuri Venkateswaran (NASA Jet Propulsion Laboratory, USA), Harald Huber (University Regensburg), BioTesc (Luzern)

Financial support: European Space Agency, FFG

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"MASE: Mars analogues for space exploration"

Involved partners: Christine Moissl-Eichinger (PI), Lisa Wink, Alexandra Perras, and the MASE team

Financial support: European Commission

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"Europlanet" 

Involved partners: Christine Moissl-Eichinger (PI), Kaisa Koskinen and the Europlanet Team

Financial support: European Commission

  read more 

"Planetary Protection"  

Involved partners: Christine Moissl-Eichinger (PI), Kaisa Koskinen, Lisa Wink

Financial support: European Space Agency, DLR

 

 

 

 

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