Diagnostik & Forschungszentrum für Molekulare BioMedizin

Medical Microbiome Research

Research focus

Unravel the impact of the human microbiome on pathogenesis, diagnosis and therapy

Most exciting results

Modulating the fecal microbiome via FMT is therapeutically effective in ulcerative colitis

Selected recent publications
  • Unterhauser K, et al. Klebsiella oxytoca enterotoxins tilimycin and tilivalline have distinct host DNA-damaging and microtubule-stabilizing activities. Proc Natl Acad Sci U S A 2019
  • Wurm P, et al. Qualitative and Quantitative DNA- and RNA-Based Analysis of the Bacterial Stomach Microbiota in Humans, Mice, and Gerbils. mSystems. 2018
  • Kump P, Wurm P, et al. The taxonomic composition of the donor intestinal microbiota is a major factor influencing the efficacy of faecal microbiota transplantation in therapy refractory ulcerative colitis. Aliment Pharmacol Ther. 2018
  • Wurm P, et al. Antibiotic-Associated Apoptotic Enterocolitis in the Absence of a Defined Pathogen: The Role of Intestinal Microbiota Depletion. Crit Care Med. 2017
  • Halwachs B, et al. Critical Issues in Mycobiota Analysis. Front Microbiol. 2017
  • Montalban-Arques A, et al. Propionibacterium acnes overabundance and natural killer group 2 member D system activation in corpus-dominant lymphocytic gastritis. J Pathol. 2016
Future plans

Development of microbiome based diagnostics and therapies

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