Sustainable living. learning. researching

Medical University of Graz

Publikationen des Forschungsfeldes: Molekulare Grundlagen Lipid-assoziierter Erkrankungen ab 2012

2018

Lichtenegger, M; Tiapko, O; Svobodova, B; Stockner, T; Glasnov, TN; Schreibmayer, W; Platzer, D; de la Cruz, GG; Krenn, S; Schober, R; Shrestha, N; Schindl, R; Romanin, C; Groschner, K
An optically controlled probe identifies lipid-gating fenestrations within the TRPC3 channel. Nat Chem Biol. 2018; 14(4):396-404
[Fulltext][PubMed]

Viaud, M; Ivanov, S; Vujic, N; Duta-Mare, M; Aira, LE; Barouillet, T; Garcia, E; Orange, F; Dugail, I; Hainault, I; Stehlik, C; Marchetti, S; Boyer, L; Guinamard, R; Foufelle, F; Bochem, A; Hovingh, KG; Thorp, EB; Gautier, EL; Kratky, D; Dasilva-Jardine, P; Yvan-Charvet, L
Lysosomal Cholesterol Hydrolysis Couples Efferocytosis to Anti-Inflammatory Oxysterol Production. Circ Res. 2018; 122(10):1369-1384
[Fulltext][PubMed]

Zatloukal, K
Bringing the cell nucleus in the focus of NAFLD. Hepatology. 2018; 67(5):1654-1656
[Fulltext][PubMed]

Maric, J; Ravindran, A; Mazzurana, L; Björklund, ÅK; Van Acker, A; Rao, A; Friberg, D; Dahlén, SE; Heinemann, A; Konya, V; Mjösberg, J
Prostaglandin E&ltsub>2&lt/sub> suppresses human group 2 innate lymphoid cell function. J Allergy Clin Immunol. 2018; 141(5):1761-1773
[Fulltext][PubMed]

Jiang, X; O Reilly, PF; Aschard, H; Hsu, YH; Richards, JB; Dupuis, J; Ingelsson, E; Karasik, D; Pilz, S; Berry, D; Kestenbaum, B; Zheng, J; Luan, J; Sofianopoulou, E; Streeten, EA; Albanes, D; Lutsey, PL; Yao, L; Tang, W; Econs, MJ; Wallaschofski, H; Völzke, H; Zhou, A; Power, C; McCarthy, MI; Michos, ED; Boerwinkle, E; Weinstein, SJ; Freedman, ND; Huang, WY; Van Schoor, NM; van der Velde, N; Groot, LCPGM; Enneman, A; Cupples, LA; Booth, SL; Vasan, RS; Liu, CT; Zhou, Y; Ripatti, S; Ohlsson, C; Vandenput, L; Lorentzon, M; Eriksson, JG; Shea, MK; Houston, DK; Kritchevsky, SB; Liu, Y; Lohman, KK; Ferrucci, L; Peacock, M; Gieger, C; Beekman, M; Slagboom, E; Deelen, J; Heemst, DV; Kleber, ME; März, W; de Boer, IH; Wood, AC; Rotter, JI; Rich, SS; Robinson-Cohen, C; den Heijer, M; Jarvelin, MR; Cavadino, A; Joshi, PK; Wilson, JF; Hayward, C; Lind, L; Michaëlsson, K; Trompet, S; Zillikens, MC; Uitterlinden, AG; Rivadeneira, F; Broer, L; Zgaga, L; Campbell, H; Theodoratou, E; Farrington, SM; Timofeeva, M; Dunlop, MG; Valdes, AM; Tikkanen, E; Lehtimäki, T; Lyytikäinen, LP; Kähönen, M; Raitakari, OT; Mikkilä, V; Ikram, MA; Sattar, N; Jukema, JW; Wareham, NJ; Langenberg, C; Forouhi, NG; Gundersen, TE; Khaw, KT; Butterworth, AS; Danesh, J; Spector, T; Wang, TJ; Hyppönen, E; Kraft, P; Kiel, DP
Genome-wide association study in 79,366 European-ancestry individuals informs the genetic architecture of 25-hydroxyvitamin D levels. Nat Commun. 2018; 9(1): 260-260.
[Fulltext][PubMed]

Rockenfeller, P; Smolnig, M; Diessl, J; Bashir, M; Schmiedhofer, V; Knittelfelder, O; Ring, J; Franz, J; Foessl, I; Khan, MJ; Rost, R; Graier, WF; Kroemer, G; Zimmermann, A; Carmona-Gutierrez, D; Eisenberg, T; Büttner, S; Sigrist, SJ; Kühnlein, RP; Kohlwein, SD; Gourlay, CW; Madeo, F
Diacylglycerol triggers Rim101 pathway-dependent necrosis in yeast: a model for lipotoxicity. Cell Death Differ. 2018; 25(4):765-781
[Fulltext][PubMed]

Montani, L; Pereira, JA; Norrmen, C; Pohl, HBF; Tinelli, E; Trotzmuller, M; Figlia, G; Dimas, P; von Niederhausern, B; Schwager, R; Jessberger, S; Semenkovich, CF; Kofeler, HC; Suter, U
De novo fatty acid synthesis by Schwann cells is essential for peripheral nervous system myelination. J CELL BIOL. 2018; 217(4): 1352-1367.
[Fulltext][PubMed]

Marsche, G
Quantifying the HDL proteome by mass spectrometry: how many proteins truly associate with HDL?. Eur J Heart Fail. 2018; 20(6):1077-1077
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Bernhart, E; Kogelnik, N; Prasch, J; Gottschalk, B; Goeritzer, M; Depaoli, MR; Reicher, H; Nusshold, C; Plastira, I; Hammer, A; Fauler, G; Malli, R; Graier, WF; Malle, E; Sattler, W
2-Chlorohexadecanoic acid induces ER stress and mitochondrial dysfunction in brain microvascular endothelial cells. Redox Biol. 2018; 15:441-451
[Fulltext][PubMed]

Schittmayer, M; Birner-Gruenberger, R; Zamboni, N
Quantification of cellular folate species by LC-MS after stabilization by derivatization. Anal Chem. 2018;
[Fulltext][PubMed]

Degendorfer, G; Chuang, CY; Mariotti, M; Hammer, A; Hoefler, G; Hägglund, P; Malle, E; Wise, SG; Davies, MJ
Exposure of tropoelastin to peroxynitrous acid gives high yields of nitrated tyrosine residues, di-tyrosine cross-links and altered protein structure and function. Free Radic Biol Med. 2018; 115:219-231
[Fulltext][PubMed]

Eroglu, E; Charoensin, S; Bischof, H; Ramadani, J; Gottschalk, B; Depaoli, MR; Waldeck-Weiermair, M; Graier, WF; Malli, R
Genetic biosensors for imaging nitric oxide in single cells. Free Radic Biol Med. 2018;
[Fulltext][PubMed]

Duta-Mare, M; Sachdev, V; Leopold, C; Kolb, D; Vujic, N; Korbelius, M; Hofer, DC; Xia, W; Huber, K; Auer, M; Gottschalk, B; Magnes, C; Graier, WF; Prokesch, A; Radovic, B; Bogner-Strauss, JG; Kratky, D
Lysosomal acid lipase regulates fatty acid channeling in brown adipose tissue to maintain thermogenesis. Biochim Biophys Acta. 2018; 1863(4):467-478
[Fulltext][PubMed]

Segerer, G; Engelmann, D; Kaestner, A; Trotzmuller, M; Kofeler, H; Stigloher, C; Thiele, C; Jeanclos, E; Gohla, A
A phosphoglycolate phosphatase/AUM-dependent link between triacylglycerol turnover and epidermal growth factor signaling. BBA-MOL CELL BIOL L. 2018; 1863(6): 584-594.
[Fulltext][PubMed]

Sun, Y; Kopp, S; Strutz, J; Gali, CC; Zandl-Lang, M; Fanaee-Danesh, E; Kirsch, A; Cvitic, S; Frank, S; Saffery, R; Björkhem, I; Desoye, G; Wadsack, C; Panzenboeck, U
Gestational diabetes mellitus modulates cholesterol homeostasis in human fetoplacental endothelium. Biochim Biophys Acta. 2018; 1863(9):968-979
[Fulltext][PubMed]

Zandl-Lang, M; Fanaee-Danesh, E; Sun, Y; Albrecher, NM; Gali, CC; Čančar, I; Kober, A; Tam-Amersdorfer, C; Stracke, A; Storck, SM; Saeed, A; Stefulj, J; Pietrzik, CU; Wilson, MR; Björkhem, I; Panzenboeck, U
Regulatory effects of simvastatin and apoJ on APP processing and amyloid-β clearance in blood-brain barrier endothelial cells. Biochim Biophys Acta. 2018; 1863(1):40-60
[Fulltext][PubMed]

Denk, H; Abuja, PM; Zatloukal, K
Animal models of NAFLD from the pathologist s point of view. Biochim Biophys Acta. 2018;
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Untersteller, K; Meissl, S; Trieb, M; Emrich, I; Zawada, A; Holzer, M; Knuplez, E; Fliser, D; Heine, G; Marsche, G
HDL functionality and cardiovascular outcome among non-dialysis chronic kidney disease patients. J Lipid Res. 2018;
[Fulltext][PubMed]

Tomin, T; Fritz, K; Gindlhuber, J; Waldherr, L; Pucher, B; Thallinger, GG; Nomura, DK; Schittmayer, M; Birner-Gruenberger, R
Deletion of Adipose Triglyceride Lipase Links Triacylglycerol Accumulation to a More-Aggressive Phenotype in A549 Lung Carcinoma Cells. J Proteome Res. 2018; 17(4):1415-1425
[Fulltext][PubMed]

Peinhaupt, M; Roula, D; Theiler, A; Sedej, M; Schicho, R; Marsche, G; Sturm, EM; Sabroe, I; Rothenberg, ME; Heinemann, A
DP1 receptor signaling prevents the onset of intrinsic apoptosis in eosinophils and functions as a transcriptional modulator. J Leukoc Biol. 2018;
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Speziali, G; Liesinger, L; Gindlhuber, J; Leopold, C; Pucher, B; Brandi, J; Castagna, A; Tomin, T; Krenn, P; Thallinger, GG; Olivieri, O; Martinelli, N; Kratky, D; Schittmayer, M; Birner-Gruenberger, R; Cecconi, D
Myristic acid induces proteomic and secretomic changes associated with steatosis, cytoskeleton remodeling, endoplasmic reticulum stress, protein turnover and exosome release in HepG2 cells. J Proteomics. 2018; 181(7):118-130
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Fellendorf, FT; Platzer, M; Pilz, R; Rieger, A; Kapfhammer, HP; Mangge, H; Dalkner, N; Zelzer, S; Meinitzer, A; Birner, A; Bengesser, SA; Queissner, R; Hamm, C; Hartleb, R; Reininghaus, EZ
Branched-chain Amino Acids are associated with Metabolic Parameters in Bipolar Disorder. World J Biol Psychiatry. 2018; 1-13
[Fulltext][PubMed]

Madreiter-Sokolowski, CT; Sokolowski, AA; Waldeck-Weiermair, M; Malli, R; Graier, WF
Targeting Mitochondria to Counteract Age-Related Cellular Dysfunction. Genes (Basel). 2018; 9(3):
[Fulltext][PubMed]

Wagner, D; Marsoner, K; Tomberger, A; Haybaeck, J; Haas, J; Werkgartner, G; Cerwenka, H; Bacher, H; Mischinger, HJ; Kornprat, P
Low skeletal muscle mass outperforms the Charlson Comorbidity Index in risk prediction in patients undergoing pancreatic resections. Eur J Surg Oncol. 2018; 44(5):658-663
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Scherz, B; Rabl, R; Flunkert, S; Rohler, S; Neddens, J; Taub, N; Temmel, M; Panzenboeck, U; Niederkofler, V; Zimmermann, R; Hutter-Paier, B
mTh1 driven expression of hTDP-43 results in typical ALS/FTLD neuropathological symptoms. PLoS One. 2018; 13(5): e0197674-e0197674.
[Fulltext][PubMed]

Durchschein, F; Krones, E; Pollheimer, MJ; Zollner, G; Wagner, M; Raufman, JP; Fickert, P
Genetic loss of the muscarinic M3 receptor markedly alters bile formation and cholestatic liver injury in mice. Hepatol Res. 2018; 48(3):E68-E77
[Fulltext][PubMed]



2017

Zechner, R; Madeo, F; Kratky, D
Cytosolic lipolysis and lipophagy: two sides of the same coin. Nat Rev Mol Cell Biol. 2017; 18(11): 671-684.
[Fulltext][PubMed]

Hartler, J; Triebl, A; Ziegl, A; Trötzmüller, M; Rechberger, GN; Zeleznik, OA; Zierler, KA; Torta, F; Cazenave-Gassiot, A; Wenk, MR; Fauland, A; Wheelock, CE; Armando, AM; Quehenberger, O; Zhang, Q; Wakelam, MJO; Haemmerle, G; Spener, F; Köfeler, HC; Thallinger, GG
Deciphering lipid structures based on platform-independent decision rules. Nat Methods. 2017; 14(12): 1171-1174.
[Fulltext][PubMed]

Zewinger, S; Kleber, ME; Rohrer, L; Lehmann, M; Triem, S; Jennings, RT; Petrakis, I; Dressel, A; Lepper, PM; Scharnagl, H; Ritsch, A; Thorand, B; Heier, M; Meisinger, C; de Las Heras Gala, T; Koenig, W; Wagenpfeil, S; Schwedhelm, E; Böger, RH; Laufs, U; von Eckardstein, A; Landmesser, U; Lüscher, TF; Fliser, D; März, W; Meinitzer, A; Speer, T
Symmetric dimethylarginine, high-density lipoproteins and cardiovascular disease. Eur Heart J. 2017; 38(20):1597-1607
[Fulltext][PubMed]

Bauer, L; Kern, S; Rogacev, KS; Emrich, IE; Zawada, A; Fliser, D; Heinemann, A; Heine, GH; Marsche, G
HDL Cholesterol Efflux Capacity and Cardiovascular Events in Patients With Chronic Kidney Disease. J Am Coll Cardiol. 2017; 69(2): 246-247.
[Fulltext][PubMed]

Zewinger, S; Kleber, ME; Tragante, V; McCubrey, RO; Schmidt, AF; Direk, K; Laufs, U; Werner, C; Koenig, W; Rothenbacher, D; Mons, U; Breitling, LP; Brenner, H; Jennings, RT; Petrakis, I; Triem, S; Klug, M; Filips, A; Blankenberg, S; Waldeyer, C; Sinning, C; Schnabel, RB; Lackner, KJ; Vlachopoulou, E; Nygård, O; Svingen, GFT; Pedersen, ER; Tell, GS; Sinisalo, J; Nieminen, MS; Laaksonen, R; Trompet, S; Smit, RAJ; Sattar, N; Jukema, JW; Groesdonk, HV; Delgado, G; Stojakovic, T; Pilbrow, AP; Cameron, VA; Richards, AM; Doughty, RN; Gong, Y; Cooper-DeHoff, R; Johnson, J; Scholz, M; Beutner, F; Thiery, J; Smith, JG; Vilmundarson, RO; McPherson, R; Stewart, AFR; Cresci, S; Lenzini, PA; Spertus, JA; Olivieri, O; Girelli, D; Martinelli, NI; Leiherer, A; Saely, CH; Drexel, H; Mündlein, A; Braund, PS; Nelson, CP; Samani, NJ; Kofink, D; Hoefer, IE; Pasterkamp, G; Quyyumi, AA; Ko, YA; Hartiala, JA; Allayee, H; Tang, WHW; Hazen, SL; Eriksson, N; Held, C; Hagström, E; Wallentin, L; Åkerblom, A; Siegbahn, A; Karp, I; Labos, C; Pilote, L; Engert, JC; Brophy, JM; Thanassoulis, G; Bogaty, P; Szczeklik, W; Kaczor, M; Sanak, M; Virani, SS; Ballantyne, CM; Lee, VV; Boerwinkle, E; Holmes, MV; Horne, BD; Hingorani, A; Asselbergs, FW; Patel, RS; GENIUS-CHD consortium; Krämer, BK; Scharnagl, H; Fliser, D; März, W; Speer, T
Relations between lipoprotein(a) concentrations, LPA genetic variants, and the risk of mortality in patients with established coronary heart disease: a molecular and genetic association study. Lancet Diabetes Endocrinol. 2017; 5(7):534-543
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Qiu, YL; Gong, JY; Feng, JY; Wang, RX; Han, J; Liu, T; Lu, Y; Li, LT; Zhang, MH; Sheps, JA; Wang, NL; Yan, YY; Li, JQ; Chen, L; Borchers, CH; Sipos, B; Knisely, AS; Ling, V; Xing, QH; Wang, JS
Defects in myosin VB are associated with a spectrum of previously undiagnosed low γ-glutamyltransferase cholestasis. HEPATOLOGY. 2017; 65(5): 1655-1669.
[Fulltext][PubMed]

Fickert, P
Bad memories from the gut may cause nightmares for the bile ducts. J Hepatol. 2017; 66(1):5-7
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Fickert, P; Hirschfield, GM; Denk, G; Marschall, HU; Altorjay, I; Färkkilä, M; Schramm, C; Spengler, U; Chapman, R; Bergquist, A; Schrumpf, E; Nevens, F; Trivedi, P; Reiter, FP; Tornai, I; Halilbasic, E; Greinwald, R; Pröls, M; Manns, MP; Trauner, M; European PSC norUDCA Study Group
norUrsodeoxycholic acid improves cholestasis in primary sclerosing cholangitis. J Hepatol. 2017; 67(3):549-558
[Fulltext][PubMed]

Hanley, J; Dhar, DK; Mazzacuva, F; Fiadeiro, R; Burden, JJ; Lyne, AM; Smith, H; Straatman-Iwanowska, A; Banushi, B; Virasami, A; Mills, K; Lemaigre, FP; Knisely, AS; Howe, S; Sebire, N; Waddington, SN; Paulusma, CC; Clayton, P; Gissen, P
Vps33b is crucial for structural and functional hepatocyte polarity. J HEPATOL. 2017; 66(5): 1001-1011.
[Fulltext][PubMed]

Bischof, H; Rehberg, M; Stryeck, S; Artinger, K; Eroglu, E; Waldeck-Weiermair, M; Gottschalk, B; Rost, R; Deak, AT; Niedrist, T; Vujic, N; Lindermuth, H; Prassl, R; Pelzmann, B; Groschner, K; Kratky, D; Eller, K; Rosenkranz, AR; Madl, T; Plesnila, N; Graier, WF; Malli, R
Novel genetically encoded fluorescent probes enable real-time detection of potassium in vitro and in vivo. Nat Commun. 2017; 8(1): 1-12.
[Fulltext][PubMed]

Grabner, GF; Zimmermann, R; Schicho, R; Taschler, U
Monoglyceride lipase as a drug target: At the crossroads of arachidonic acid metabolism and endocannabinoid signaling. Pharmacol Ther. 2017; 175(6):35-46
[Fulltext][PubMed]

Mueller, KM; Hartmann, K; Kaltenecker, D; Vettorazzi, S; Bauer, M; Mauser, L; Amann, S; Jall, S; Fischer, K; Esterbauer, H; Müller, TD; Tschöp, MH; Magnes, C; Haybaeck, J; Scherer, T; Bordag, N; Tuckermann, JP; Moriggl, R
Adipocyte Glucocorticoid Receptor Deficiency Attenuates Aging- and HFD-Induced Obesity and Impairs the Feeding-Fasting Transition. Diabetes. 2017; 66(2):272-286
[Fulltext][PubMed]

Holzer, M; Trieb, M; Marsche, G
The complex high-density lipoprotein proteome: a matter of purification?. Kidney Int. 2017; 92(6): 1555-1555.
[Fulltext][PubMed]

Silbernagel, G; Pagel, P; Pfahlert, V; Genser, B; Scharnagl, H; Kleber, ME; Delgado, G; Ohrui, H; Ritsch, A; Grammer, TB; Koenig, W; Marz, W
High-Density Lipoprotein Subclasses, Coronary Artery Disease, and Cardiovascular Mortality. CLIN CHEM. 2017; 63(12): 1886-1896.
[Fulltext]

Wu, BJ; Li, Y; Ong, KL; Sun, Y; Shrestha, S; Hou, L; Johns, D; Barter, PJ; Rye, KA
Reduction of In-Stent Restenosis by Cholesteryl Ester Transfer Protein Inhibition. ARTERIOSCL THROM VAS. 2017; 37(12): 2333-2341.
[Fulltext][PubMed]

Grond, S; Eichmann, TO; Dubrac, S; Kolb, D; Schmuth, M; Fischer, J; Crumrine, D; Elias, PM; Haemmerle, G; Zechner, R; Lass, A; Radner, FP
PNPLA1 Deficiency in Mice and Humans Leads to a Defect in the Synthesis of Omega-O-Acylceramides. J Invest Dermatol. 2017; 137(2): 394-402.
[Fulltext][PubMed]

Grond, S; Radner, FP; Eichmann, TO; Kolb, D; Grabner, GF; Wolinski, H; Gruber, R; Hofer, P; Heier, C; Schauer, S; Rülicke, T; Hoefler, G; Schmuth, M; Elias, PM; Lass, A; Zechner, R; Haemmerle, G
Skin Barrier Development Depends on CGI-58 Protein Expression during Late-Stage Keratinocyte Differentiation. J Invest Dermatol. 2017; 137(2): 403-413.
[Fulltext][PubMed]

Graff, M; Scott, RA; Justice, AE; Young, KL; Feitosa, MF; Barata, L; Winkler, TW; Chu, AY; Mahajan, A; Hadley, D; Xue, L; Workalemahu, T; Heard-Costa, NL; den Hoed, M; Ahluwalia, TS; Qi, Q; Ngwa, JS; Renström, F; Quaye, L; Eicher, JD; Hayes, JE; Cornelis, M; Kutalik, Z; Lim, E; Luan, J; Huffman, JE; Zhang, W; Zhao, W; Griffin, PJ; Haller, T; Ahmad, S; Marques-Vidal, PM; Bien, S; Yengo, L; Teumer, A; Smith, AV; Kumari, M; Harder, MN; Justesen, JM; Kleber, ME; Hollensted, M; Lohman, K; Rivera, NV; Whitfield, JB; Zhao, JH; Stringham, HM; Lyytikäinen, LP; Huppertz, C; Willemsen, G; Peyrot, WJ; Wu, Y; Kristiansson, K; Demirkan, A; Fornage, M; Hassinen, M; Bielak, LF; Cadby, G; Tanaka, T; Mägi, R; van der Most, PJ; Jackson, AU; Bragg-Gresham, JL; Vitart, V; Marten, J; Navarro, P; Bellis, C; Pasko, D; Johansson, Å; Snitker, S; Cheng, YC; Eriksson, J; Lim, U; Aadahl, M; Adair, LS; Amin, N; Balkau, B; Auvinen, J; Beilby, J; Bergman, RN; Bergmann, S; Bertoni, AG; Blangero, J; Bonnefond, A; Bonnycastle, LL; Borja, JB; Brage, S; Busonero, F; Buyske, S; Campbell, H; Chines, PS; Collins, FS; Corre, T; Smith, GD; Delgado, GE; Dueker, N; Dörr, M; Ebeling, T; Eiriksdottir, G; Esko, T; Faul, JD; Fu, M; Færch, K; Gieger, C; Gläser, S; Gong, J; Gordon-Larsen, P; Grallert, H; Grammer, TB; Grarup, N; van Grootheest, G; Harald, K; Hastie, ND; Havulinna, AS; Hernandez, D; Hindorff, L; Hocking, LJ; Holmens, OL; Holzapfel, C; Hottenga, JJ; Huang, J; Huang, T; Hui, J; Huth, C; Hutri-Kähönen, N; James, AL; Jansson, JO; Jhun, MA; Juonala, M; Kinnunen, L; Koistinen, HA; Kolcic, I; Komulainen, P; Kuusisto, J; Kvaløy, K; Kähönen, M; Lakka, TA; Launer, LJ; Lehne, B; Lindgren, CM; Lorentzon, M; Luben, R; Marre, M; Milaneschi, Y; Monda, KL; Montgomery, GW; De Moor, MHM; Mulas, A; Müller-Nurasyid, M; Musk, AW; Männikkö, R; Männistö, S; Narisu, N; Nauck, M; Nettleton, JA; Nolte, IM; Oldehinkel, AJ; Olden, M; Ong, KK; Padmanabhan, S; Paternoster, L; Perez, J; Perola, M; Peters, A; Peters, U; Peyser, PA; Prokopenko, I; Puolijoki, H; Raitakari, OT; Rankinen, T; Rasmussen-Torvik, LJ; Rawal, R; Ridker, PM; Rose, LM; Rudan, I; Sarti, C; Sarzynski, MA; Savonen, K; Scott, WR; Sanna, S; Shuldiner, AR; Sidney, S; Silbernagel, G; Smith, BH; Smith, JA; Snieder, H; Stančáková, A; Sternfeld, B; Swift, AJ; Tammelin, T; Tan, ST; Thorand, B; Thuillier, D; Vandenput, L; Vestergaard, H; van Vliet-Ostaptchouk, JV; Vohl, MC; Völker, U; Waeber, G; Walker, M; Wild, S; Wong, A; Wright, AF; Zillikens, MC; Zubair, N; Haiman, CA; Lemarchand, L; Gyllensten, U; Ohlsson, C; Hofman, A; Rivadeneira, F; Uitterlinden, AG; Pérusse, L; Wilson, JF; Hayward, C; Polasek, O; Cucca, F; Hveem, K; Hartman, CA; Tönjes, A; Bandinelli, S; Palmer, LJ; Kardia, SLR; Rauramaa, R; Sørensen, TIA; Tuomilehto, J; Salomaa, V; Penninx, BWJH; de Geus, EJC; Boomsma, DI; Lehtimäki, T; Mangino, M; Laakso, M; Bouchard, C; Martin, NG; Kuh, D; Liu, Y; Linneberg, A; März, W; Strauch, K; Kivimäki, M; Harris, TB; Gudnason, V; Völzke, H; Qi, L; Järvelin, MR; Chambers, JC; Kooner, JS; Froguel, P; Kooperberg, C; Vollenweider, P; Hallmans, G; Hansen, T; Pedersen, O; Metspalu, A; Wareham, NJ; Langenberg, C; Weir, DR; Porteous, DJ; Boerwinkle, E; Chasman, DI; CHARGE Consortium; EPIC-InterAct Consortium; PAGE Consortium; Abecasis, GR; Barroso, I; McCarthy, MI; Frayling, TM; O Connell, JR; van Duijn, CM; Boehnke, M; Heid, IM; Mohlke, KL; Strachan, DP; Fox, CS; Liu, CT; Hirschhorn, JN; Klein, RJ; Johnson, AD; Borecki, IB; Franks, PW; North, KE; C
Genome-wide physical activity interactions in adiposity - A meta-analysis of 200,452 adults. PLoS Genet. 2017; 13(4): e1006528-e1006528.
[Fulltext][PubMed]

Delgado, GE; Kramer, BK; Lorkowski, S; Marz, W; von Schacky, C; Kleber, ME
Individual omega-9 monounsaturated fatty acids and mortality-The Ludwigshafen Risk and Cardiovascular Health Study. J CLIN LIPIDOL. 2017; 11(1): 126-135.
[Fulltext][PubMed]

Delgado, GE; März, W; Lorkowski, S; von Schacky, C; Kleber, ME
Omega-6 fatty acids: Opposing associations with risk-The Ludwigshafen Risk and Cardiovascular Health Study. J CLIN LIPIDOL. 2017; 11(4): 1082-1090.
[Fulltext][PubMed]

Winklhofer-Roob, BM; Faustmann, G; Roob, JM
Low-density lipoprotein oxidation biomarkers in human health and disease and effects of bioactive compounds. FREE RADICAL BIO MED. 2017; 111(1): 38-86.
[Fulltext][PubMed]

Hofer, DC; Pessentheiner, AR; Pelzmann, HJ; Schlager, S; Madreiter-Sokolowski, CT; Kolb, D; Eichmann, TO; Rechberger, G; Bilban, M; Graier, WF; Kratky, D; Bogner-Strauss, JG
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Schliefsteiner, C; Hirschmugl, B; Kopp, S; Curcic, S; Bernhart, EM; Marsche, G; Lang, U; Desoye, G; Wadsack, C
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Comparison of HapMap and 1000 Genomes Reference Panels in a Large-Scale Genome-Wide Association Study. PLOS ONE. 2017; 12(1): e0167742
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Lelu, S; Afadzi, M; Berg, S; Aslund, AK; Torp, SH; Sattler, W; de L Davies, C
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Li, JQ; Qiu, YL; Gong, JY; Dou, LM; Lu, Y; Knisely, AS; Zhang, MH; Luan, WS; Wang, JS
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2016

Hou, L; Heilbronner, U; Degenhardt, F; Adli, M; Akiyama, K; Akula, N; Ardau, R; Arias, B; Backlund, L; Banzato, CE; Benabarre, A; Bengesser, S; Bhattacharjee, AK; Biernacka, JM; Birner, A; Brichant-Petitjean, C; Bui, ET; Cervantes, P; Chen, GB; Chen, HC; Chillotti, C; Cichon, S; Clark, SR; Colom, F; Cousins, DA; Cruceanu, C; Czerski, PM; Dantas, CR; Dayer, A; Étain, B; Falkai, P; Forstner, AJ; Frisén, L; Fullerton, JM; Gard, S; Garnham, JS; Goes, FS; Grof, P; Gruber, O; Hashimoto, R; Hauser, J; Herms, S; Hoffmann, P; Hofmann, A; Jamain, S; Jiménez, E; Kahn, JP; Kassem, L; Kittel-Schneider, S; Kliwicki, S; König, B; Kusumi, I; Lackner, N; Laje, G; Landén, M; Lavebratt, C; Leboyer, M; Leckband, SG; Jaramillo, CA; MacQueen, G; Manchia, M; Martinsson, L; Mattheisen, M; McCarthy, MJ; McElroy, SL; Mitjans, M; Mondimore, FM; Monteleone, P; Nievergelt, CM; Nöthen, MM; Ösby, U; Ozaki, N; Perlis, RH; Pfennig, A; Reich-Erkelenz, D; Rouleau, GA; Schofield, PR; Schubert, KO; Schweizer, BW; Seemüller, F; Severino, G; Shekhtman, T; Shilling, PD; Shimoda, K; Simhandl, C; Slaney, CM; Smoller, JW; Squassina, A; Stamm, T; Stopkova, P; Tighe, SK; Tortorella, A; Turecki, G; Volkert, J; Witt, S; Wright, A; Young, LT; Zandi, PP; Potash, JB; DePaulo, JR; Bauer, M; Reininghaus, EZ; Novák, T; Aubry, JM; Maj, M; Baune, BT; Mitchell, PB; Vieta, E; Frye, MA; Rybakowski, JK; Kuo, PH; Kato, T; Grigoroiu-Serbanescu, M; Reif, A; Del Zompo, M; Bellivier, F; Schalling, M; Wray, NR; Kelsoe, JR; Alda, M; Rietschel, M; McMahon, FJ; Schulze, TG
Genetic variants associated with response to lithium treatment in bipolar disorder: a genome-wide association study. Lancet. 2016; 387(10023):1085-1093
[Fulltext][PubMed]

Laaksonen, R; Ekroos, K; Sysi-Aho, M; Hilvo, M; Vihervaara, T; Kauhanen, D; Suoniemi, M; Hurme, R; März, W; Scharnagl, H; Stojakovic, T; Vlachopoulou, E; Lokki, ML; Nieminen, MS; Klingenberg, R; Matter, CM; Hornemann, T; Jüni, P; Rodondi, N; Räber, L; Windecker, S; Gencer, B; Pedersen, ER; Tell, GS; Nygård, O; Mach, F; Sinisalo, J; Lüscher, TF
Plasma ceramides predict cardiovascular death in patients with stable coronary artery disease and acute coronary syndromes beyond LDL-cholesterol. Eur Heart J. 2016; 37(25):1967-1976
[Fulltext][PubMed]

Marz, W; Ritsch, A
Cholesterol Efflux Capacity Choke Point of Reverse Cholesterol Traffic?. J AM COLL CARDIOL. 2016; 67(21): 2488-2491.
[Fulltext][PubMed]

Krones, E; Wagner, M
Fibroblast growth factor 19 meets mammalian target of rapamycin: A mitogenic Tête-à-Tête under consideration. Hepatology. 2016; 64(4):1028-1030
[Fulltext][PubMed]

Wagner, M; Choi, S; Panzitt, K; Mamrosh, JL; Lee, JM; Zaufel, A; Xiao, R; Wooton-Kee, R; Ståhlman, M; Newgard, CB; Borén, J; Moore, DD
Liver receptor homolog-1 is a critical determinant of methyl-pool metabolism. Hepatology. 2016; 63(1):95-106
[Fulltext][PubMed]

Wagner, M; Fickert, P; Zollner, G
Secretin and cholestasis, two sides of a coin. Hepatology. 2016; 64(3):714-716
[Fulltext][PubMed]

Jandl, K; Stacher, E; Bálint, Z; Sturm, EM; Maric, J; Peinhaupt, M; Luschnig, P; Aringer, I; Fauland, A; Konya, V; Dahlen, SE; Wheelock, CE; Kratky, D; Olschewski, A; Marsche, G; Schuligoi, R; Heinemann, A
Activated prostaglandin D2 receptors on macrophages enhance neutrophil recruitment into the lung. J Allergy Clin Immunol. 2016; 137(3):833-843
[Fulltext][PubMed]

Bartuzi, P; Billadeau, DD; Favier, R; Rong, S; Dekker, D; Fedoseienko, A; Fieten, H; Wijers, M; Levels, JH; Huijkman, N; Kloosterhuis, N; van der Molen, H; Brufau, G; Groen, AK; Elliott, AM; Kuivenhoven, JA; Plecko, B; Grangl, G; McGaughran, J; Horton, JD; Burstein, E; Hofker, MH; van de Sluis, B
CCC- and WASH-mediated endosomal sorting of LDLR is required for normal clearance of circulating LDL. Nat Commun. 2016; 7(5):10961-10961
[Fulltext][PubMed]

Eroglu, E; Gottschalk, B; Charoensin, S; Blass, S; Bischof, H; Rost, R; Madreiter-Sokolowski, CT; Pelzmann, B; Bernhart, E; Sattler, W; Hallström, S; Malinski, T; Waldeck-Weiermair, M; Graier, WF; Malli, R
Development of novel FP-based probes for live-cell imaging of nitric oxide dynamics. Nat Commun. 2016; 7(3):10623-10623
[Fulltext][PubMed]

Roier, S; Zingl, FG; Cakar, F; Durakovic, S; Kohl, P; Eichmann, TO; Klug, L; Gadermaier, B; Weinzerl, K; Prassl, R; Lass, A; Daum, G; Reidl, J; Feldman, MF; Schild, S
A novel mechanism for the biogenesis of outer membrane vesicles in Gram-negative bacteria. Nat Commun. 2016; 7(412):10515-10515
[Fulltext][PubMed]

Walford, GA; Gustafsson, S; Rybin, D; Stančáková, A; Chen, H; Liu, CT; Hong, J; Jensen, RA; Rice, K; Morris, AP; Mägi, R; Tönjes, A; Prokopenko, I; Kleber, ME; Delgado, G; Silbernagel, G; Jackson, AU; Appel, EV; Grarup, N; Lewis, JP; Montasser, ME; Landenvall, C; Staiger, H; Luan, J; Frayling, TM; Weedon, MN; Xie, W; Morcillo, S; Martínez-Larrad, MT; Biggs, ML; Chen, YD; Corbaton-Anchuelo, A; Færch, K; Gómez-Zumaquero, JM; Goodarzi, MO; Kizer, JR; Koistinen, HA; Leong, A; Lind, L; Lindgren, C; Machicao, F; Manning, AK; Martín-Núñez, GM; Rojo-Martínez, G; Rotter, JI; Siscovick, DS; Zmuda, JM; Zhang, Z; Serrano-Rios, M; Smith, U; Soriguer, F; Hansen, T; Jørgensen, TJ; Linnenberg, A; Pedersen, O; Walker, M; Langenberg, C; Scott, RA; Wareham, NJ; Fritsche, A; Häring, HU; Stefan, N; Groop, L; O Connell, JR; Boehnke, M; Bergman, RN; Collins, FS; Mohlke, KL; Tuomilehto, J; März, W; Kovacs, P; Stumvoll, M; Psaty, BM; Kuusisto, J; Laakso, M; Meigs, JB; Dupuis, J; Ingelsson, E; Florez, JC
Genome-Wide Association Study of the Modified Stumvoll Insulin Sensitivity Index Identifies BCL2 and FAM19A2 as Novel Insulin Sensitivity Loci. Diabetes. 2016; 65(10): 3200-3211.
[Fulltext][PubMed]

Klionsky, DJ; Abdelmohsen, K; Abe, A; Abedin, MJ; Abeliovich, H; Acevedo Arozena, A; Adachi, H; Adams, CM; Adams, PD; Adeli, K; Adhihetty, PJ; Adler, SG; Agam, G; Agarwal, R; ... Malli, R; ... Sedej, S; ... et al.
Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition). Autophagy. 2016; 12(1): 1-222.
[Fulltext][PubMed]

Krane, V; Schmidt, KR; Gutjahr-Lengsfeld, LJ; Mann, JF; März, W; Swoboda, F; Wanner, C; 4D Study Investigators (the German Diabetes and Dialysis Study Investigators)
Long-term effects following 4 years of randomized treatment with atorvastatin in patients with type 2 diabetes mellitus on hemodialysis. KIDNEY INT. 2016; 89(6): 1380-1387.
[Fulltext][PubMed]

Huang, J; Li, L; Lian, J; Schauer, S; Vesely, PW; Kratky, D; Hoefler, G; Lehner, R
Tumor-Induced Hyperlipidemia Contributes to Tumor Growth. Cell Rep. 2016; 15(2): 336-348.
[Fulltext][PubMed]

Frei, RB; Luschnig, P; Parzmair, GP; Peinhaupt, M; Schranz, S; Fauland, A; Wheelock, CE; Heinemann, A; Sturm, EM
Cannabinoid receptor 2 augments eosinophil responsiveness and aggravates allergen-induced pulmonary inflammation in mice. Allergy. 2016; 71(7):944-956
[Fulltext][PubMed]

Derler, I; Jardin, I; Stathopulos, PB; Muik, M; Fahrner, M; Zayats, V; Pandey, SK; Poteser, M; Lackner, B; Absolonova, M; Schindl, R; Groschner, K; Ettrich, R; Ikura, M; Romanin, C
Cholesterol modulates Orai1 channel function. Sci Signal. 2016; 9(412):ra10-ra10
[Fulltext][PubMed]

Giroud, M; Pisani, DF; Karbiener, M; Barquissau, V; Ghandour, RA; Tews, D; Fischer-Posovszky, P; Chambard, JC; Knippschild, U; Niemi, T; Taittonen, M; Nuutila, P; Wabitsch, M; Herzig, S; Virtanen, KA; Langin, D; Scheideler, M; Amri, EZ
miR-125b affects mitochondrial biogenesis and impairs brite adipocyte formation and function. Mol Metab. 2016; 5(8): 615-625.
[Fulltext][PubMed]

Tardelli, M; Zeyda, K; Moreno-Viedma, V; Wanko, B; Grün, NG; Staffler, G; Zeyda, M; Stulnig, TM
Osteopontin is a key player for local adipose tissue macrophage proliferation in obesity. Mol Metab. 2016; 5(11): 1131-1137.
[Fulltext][PubMed]

Roeseler, E; Julius, U; Heigl, F; Spitthoever, R; Heutling, D; Breitenberger, P; Leebmann, J; Lehmacher, W; Kamstrup, PR; Nordestgaard, BG; Maerz, W; Noureen, A; Schmidt, K; Kronenberg, F; Heibges, A; Klingel, R; Pro(a)LiFe-Study Group
Lipoprotein Apheresis for Lipoprotein(a)-Associated Cardiovascular Disease: Prospective 5 Years of Follow-Up and Apolipoprotein(a) Characterization. ARTERIOSCL THROM VAS. 2016; 36(9): 2019-2027.
[Fulltext][PubMed]

Radović, B; Vujić, N; Leopold, C; Schlager, S; Goeritzer, M; Patankar, JV; Korbelius, M; Kolb, D; Reindl, J; Wegscheider, M; Tomin, T; Birner-Gruenberger, R; Schittmayer, M; Groschner, L; Magnes, C; Diwoky, C; Frank, S; Steyrer, E; Du, H; Graier, WF; Madl, T; Kratky, D
Lysosomal acid lipase regulates VLDL synthesis and insulin sensitivity in mice. Diabetologia. 2016; 59(8):1743-1752
[Fulltext][PubMed]

Radnai, B; Sturm, EM; Stančić, A; Jandl, K; Labocha, S; Ferreirós, N; Grill, M; Hasenoehrl, C; Gorkiewicz, G; Marsche, G; Heinemann, Á; Högenauer, C; Schicho, R
Eosinophils Contribute to Intestinal Inflammation via Chemoattractant Receptor-homologous Molecule Expressed on Th2 Cells, CRTH2, in Experimental Crohn s Disease. J Crohns Colitis. 2016; 10(9):1087-1095
[Fulltext][PubMed]

Degendorfer, G; Chuang, CY; Kawasaki, H; Hammer, A; Malle, E; Yamakura, F; Davies, MJ
Peroxynitrite-mediated oxidation of plasma fibronectin. Free Radic Biol Med. 2016; 97:602-615
[Fulltext][PubMed]

Nusshold, C; Üllen, A; Kogelnik, N; Bernhart, E; Reicher, H; Plastira, I; Glasnov, T; Zangger, K; Rechberger, G; Kollroser, M; Fauler, G; Wolinski, H; Weksler, BB; Romero, IA; Kohlwein, SD; Couraud, PO; Malle, E; Sattler, W
Assessment of electrophile damage in a human brain endothelial cell line utilizing a clickable alkyne analog of 2-chlorohexadecanal. Free Radic Biol Med. 2016; 90: 59-74.
[Fulltext][PubMed]

Aschauer, P; Rengachari, S; Lichtenegger, J; Schittmayer, M; Das, KM; Mayer, N; Breinbauer, R; Birner-Gruenberger, R; Gruber, CC; Zimmermann, R; Gruber, K; Oberer, M
Crystal structure of the Saccharomyces cerevisiae monoglyceride lipase Yju3p. Biochim Biophys Acta. 2016; 1861(5):462-470
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Sachdev, V; Leopold, C; Bauer, R; Patankar, JV; Iqbal, J; Obrowsky, S; Boverhof, R; Doktorova, M; Scheicher, B; Goeritzer, M; Kolb, D; Turnbull, AV; Zimmer, A; Hoefler, G; Hussain, MM; Groen, AK; Kratky, D
Novel role of a triglyceride-synthesizing enzyme: DGAT1 at the crossroad between triglyceride and cholesterol metabolism. Biochim Biophys Acta. 2016; 1861(9 Pt A):1132-1141
[Fulltext][PubMed]

Trieb, M; Horvath, A; Birner-Gruenberger, R; Spindelboeck, W; Stadlbauer, V; Taschler, U; Curcic, S; Stauber, RE; Holzer, M; Pasterk, L; Heinemann, A; Marsche, G
Liver disease alters high-density lipoprotein composition, metabolism and function. Biochim Biophys Acta. 2016; 1861(7):630-638
[Fulltext][PubMed]

Vogl, F; Humpolickova, J; Amaro, M; Koller, D; Kofeler, H; Zenzmaier, E; Hof, M; Hermetter, A
Role of protein kinase C delta in apoptotic signaling of oxidized phospholipids in RAW 264.7 macrophages BBA-MOL CELL BIOL L. 2016; 1861(4): 320-330.
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Kargl, J; Andersen, L; Hasenöhrl, C; Feuersinger, D; Stančić, A; Fauland, A; Magnes, C; El-Heliebi, A; Lax, S; Uranitsch, S; Haybaeck, J; Heinemann, A; Schicho, R
GPR55 promotes migration and adhesion of colon cancer cells indicating a role in metastasis. Br J Pharmacol. 2016; 173(1): 142-154.
[Fulltext][PubMed]

Al-Zoughbi, W; Pichler, M; Gorkiewicz, G; Guertl-Lackner, B; Haybaeck, J; Jahn, SW; Lackner, C; Liegl-Atzwanger, B; Popper, H; Schauer, S; Nusshold, E; Kindt, AS; Trajanoski, Z; Speicher, MR; Haemmerle, G; Zimmermann, R; Zechner, R; Vesely, PW; Hoefler, G
Loss of adipose triglyceride lipase is associated with human cancer and induces mouse pulmonary neoplasia. Oncotarget. 2016; 13(5):
[Fulltext][PubMed]

Bettermann, K; Mehta, AK; Hofer, EM; Wohlrab, C; Golob-Schwarzl, N; Svendova, V; Schimek, MG; Stumptner, C; Thuringer, A; Speicher, MR; Lackner, C; Zatloukal, K; Denk, H; Haybaeck, J
Keratin 18-deficiency results in steatohepatitis and liver tumors in old mice: A model of steatohepatitis-associated liver carcinogenesis. ONCOTARGET. 2016; 7(45): 73309-73322.
[Fulltext][PubMed]

Meshcheryakova, A; Svoboda, M; Tahir, A; Kofeler, HC; Triebl, A; Mungenast, F; Heinze, G; Gerner, C; Zimmermann, P; Jaritz, M; Mechtcheriakova, D
Exploring the role of sphingolipid machinery during the epithelial to mesenchymal transition program using an integrative approach. ONCOTARGET. 2016; 7(16): 22295-22323.
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Plastira, I; Bernhart, E; Goeritzer, M; Reicher, H; Kumble, VB; Kogelnik, N; Wintersperger, A; Hammer, A; Schlager, S; Jandl, K; Heinemann, A; Kratky, D; Malle, E; Sattler, W
1-Oleyl-lysophosphatidic acid (LPA) promotes polarization of BV-2 and primary murine microglia towards an M1-like phenotype. J Neuroinflammation. 2016; 13(1): 205-205.
[Fulltext][PubMed]

Grün, NG; Zeyda, K; Moreno-Viedma, V; Strohmeier, K; Staffler, G; Zeyda, M; Stulnig, TM
A humanized osteopontin mouse model and its application in immunometabolic obesity studies. Transl Res. 2016; 178(6): 63-73.
[Fulltext][PubMed]

Koyani, CN; Kitz, K; Rossmann, C; Bernhart, E; Huber, E; Trummer, C; Windischhofer, W; Sattler, W; Malle, E
Activation of the MAPK/Akt/Nrf2-Egr1/HO-1-GCLc axis protects MG-63 osteosarcoma cells against 15d-PGJ2-mediated cell death. Biochem Pharmacol. 2016; 104:29-41
[Fulltext][PubMed]

Kollerits, B; Drechsler, C; Krane, V; Lamina, C; Marz, W; Dieplinger, H; Ritz, E; Wanner, C; Kronenberg, F
Lipoprotein(a) concentrations, apolipoprotein(a) isoforms and clinical endpoints in haemodialysis patients with type 2 diabetes mellitus: results from the 4D Study. NEPHROL DIAL TRANSPL. 2016; 31(11): 1901-1908.
[Fulltext][PubMed]

Leis, HJ; Windischhofer, W
Calcium-independent phospholipases A2 in murine osteoblastic cells and their inhibition by bromoenol lactone: impact on arachidonate dynamics and prostaglandin synthesis. J Enzyme Inhib Med Chem. 2016; 31(6): 1203-1213.
[Fulltext][PubMed]

Giroud, M; Karbiener, M; Pisani, DF; Ghandour, RA; Beranger, GE; Niemi, T; Taittonen, M; Nuutila, P; Virtanen, KA; Langin, D; Scheideler, M; Amri, EZ
Let-7i-5p represses brite adipocyte function in mice and humans. Sci Rep. 2016; 6:28613-28613
[Fulltext][PubMed]

Holzer, M; Kern, S; Birner-Grünberger, R; Curcic, S; Heinemann, A; Marsche, G
Refined purification strategy for reliable proteomic profiling of HDL2/3: Impact on proteomic complexity. Sci Rep. 2016; 6:38533-38533
[Fulltext][PubMed]

Pasterk, L; Lemesch, S; Leber, B; Trieb, M; Curcic, S; Stadlbauer, V; Schuligoi, R; Schicho, R; Heinemann, A; Marsche, G
Oxidized plasma albumin promotes platelet-endothelial crosstalk and endothelial tissue factor expression. Sci Rep. 2016; 6:22104-22104
[Fulltext][PubMed]

Poteser, M; Leitinger, G; Pritz, E; Platzer, D; Frischauf, I; Romanin, C; Groschner, K
Live-cell imaging of ER-PM contact architecture by a novel TIRFM approach reveals extension of junctions in response to store-operated Ca(2+)-entry. Sci Rep. 2016; 6: 35656-35656.
[Fulltext][PubMed]

Prokesch, A; Pelzmann, HJ; Pessentheiner, AR; Huber, K; Madreiter-Sokolowski, CT; Drougard, A; Schittmayer, M; Kolb, D; Magnes, C; Trausinger, G; Graier, WF; Birner-Gruenberger, R; Pospisilik, JA; Bogner-Strauss, JG
N-acetylaspartate catabolism determines cytosolic acetyl-CoA levels and histone acetylation in brown adipocytes. Sci Rep. 2016; 6(3):23723-23723
[Fulltext][PubMed]

Themanns, M; Mueller, KM; Kessler, SM; Golob-Schwarzl, N; Mohr, T; Kaltenecker, D; Bourgeais, J; Paier-Pourani, J; Friedbichler, K; Schneller, D; Schlederer, M; Zebedin-Brandl, E; Terracciano, LM; Han, X; Kenner, L; Wagner, KU; Mikulits, W; Kozlov, AV; Heim, MH; Gouilleux, F; Haybaeck, J; Moriggl, R
Hepatic Deletion of Janus Kinase 2 Counteracts Oxidative Stress in Mice. Sci Rep. 2016; 6: 34719-34719.
[Fulltext][PubMed]

Grenkowitz, T; Kassner, U; Wühle-Demuth, M; Salewsky, B; Rosada, A; Zemojtel, T; Hopfenmüller, W; Isermann, B; Borucki, K; Heigl, F; Laufs, U; Wagner, S; Kleber, ME; Binner, P; März, W; Steinhagen-Thiessen, E; Demuth, I
Clinical characterization and mutation spectrum of German patients with familial hypercholesterolemia. ATHEROSCLEROSIS. 2016; 253(11): 88-93.
[Fulltext][PubMed]

Kleber, ME; Delgado, GE; Lorkowski, S; März, W; von Schacky, C
Omega-3 fatty acids and mortality in patients referred for coronary angiography. The Ludwigshafen Risk and Cardiovascular Health Study. ATHEROSCLEROSIS. 2016; 252(3): 175-181.
[Fulltext][PubMed]

Vujic, N; Schlager, S; Eichmann, TO; Madreiter-Sokolowski, CT; Goeritzer, M; Rainer, S; Schauer, S; Rosenberger, A; Woelfler, A; Doddapattar, P; Zimmermann, R; Hoefler, G; Lass, A; Graier, WF; Radovic, B; Kratky, D
Monoglyceride lipase deficiency modulates endocannabinoid signaling and improves plaque stability in ApoE-knockout mice. Atherosclerosis. 2016; 244(6): 9-21.
[Fulltext][PubMed]

Vinod, M; Patankar, JV; Sachdev, V; Frank, S; Graier, WF; Kratky, D; Kostner, GM
MiR-206 is expressed in pancreatic islets and regulates glucokinase activity. Am J Physiol Endocrinol Metab. 2016; 311(1): E175-E185.
[Fulltext][PubMed]

Kessler, SM; Laggai, S; Van Wonterg, E; Gemperlein, K; Müller, R; Haybaeck, J; Vandenbroucke, RE; Ogris, M; Libert, C; Kiemer, AK
Transient Hepatic Overexpression of Insulin-Like Growth Factor 2 Induces Free Cholesterol and Lipid Droplet Formation. Front Physiol. 2016; 7(5):147-147
[Fulltext][PubMed]

Grumet, L; Eichmann, TO; Taschler, U; Zierler, KA; Leopold, C; Moustafa, T; Radovic, B; Romauch, M; Yan, C; Du, H; Haemmerle, G; Zechner, R; Fickert, P; Kratky, D; Zimmermann, R; Lass, A
Lysosomal Acid Lipase Hydrolyzes Retinyl Ester and Affects Retinoid Turnover. J Biol Chem. 2016; 291(34):17977-17987
[Fulltext][PubMed]

Kawala, MA; Bohndorf, M; Graffmann, N; Wruck, W; Zatloukal, K; Adjaye, J
Characterization of dermal fibroblast-derived iPSCs from a patient with low grade steatosis. Stem Cell Res. 2016; 17(3):547-549
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Kawala, MA; Bohndorf, M; Graffmann, N; Wruck, W; Zatloukal, K; Adjaye, J
Characterization of iPSCs derived from dermal fibroblasts from a healthy 19year old female. Stem Cell Res. 2016; 17(3):597-599
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Kawala, MA; Bohndorf, M; Graffmann, N; Wruck, W; Zatloukal, K; Adjaye, J
Characterization of dermal fibroblast-derived iPSCs from a patient with high grade steatosis. Stem Cell Res. 2016; 17(3):568-571
[Fulltext][PubMed]

Tomazic, PV; Birner-Gruenberger, R; Leitner, A; Spoerk, S; Lang-Loidolt, D
Seasonal proteome changes of nasal mucus reflect perennial inflammatory response and reduced defence mechanisms and plasticity in allergic rhinitis. J Proteomics. 2016; 133(1):153-160
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Schuch, K; Wanko, B; Ambroz, K; Castelo-Rosa, A; Moreno-Viedma, V; Grün, NG; Leitner, L; Staffler, G; Zeyda, M; Stulnig, TM
Osteopontin affects macrophage polarization promoting endocytic but not inflammatory properties. Obesity (Silver Spring). 2016; 24(7): 1489-1498.
[Fulltext][PubMed]

Theiler, A; Konya, V; Pasterk, L; Maric, J; Bärnthaler, T; Lanz, I; Platzer, W; Schuligoi, R; Heinemann, A
The EP1/EP3 receptor agonist 17-pt-PGE2 acts as an EP4 receptor agonist on endothelial barrier function and in a model of LPS-induced pulmonary inflammation. Vascul Pharmacol. 2016; 87: 180-189.
[Fulltext][PubMed]

Svobodova, B; Groschner, K
Mechanisms of lipid regulation and lipid gating in TRPC channels. CELL CALCIUM. 2016; 59(6): 271-279.
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Hasenoehrl, C; Taschler, U; Storr, M; Schicho, R
The gastrointestinal tract - a central organ of cannabinoid signaling in health and disease. Neurogastroenterol Motil. 2016; 28(12):1765-1780
[Fulltext][PubMed]

Gouni-Berthold, I; Descamps, OS; Fraass, U; Hartfield, E; Allcott, K; Dent, R; Marz, W
Systematic review of published Phase 3 data on anti-PCSK9 monoclonal antibodies in patients with hypercholesterolaemia. BRIT J CLIN PHARMACO. 2016; 82(6): 1412-1443.
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Hartmann, P; Seebauer, CT; Mazagova, M; Horvath, A; Wang, L; Llorente, C; Varki, NM; Brandl, K; Ho, SB; Schnabl, B
Deficiency of intestinal mucin-2 protects mice from diet-induced fatty liver disease and obesity. Am J Physiol Gastrointest Liver Physiol. 2016; 310(5):G310-G322
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Reiter, FP; Wimmer, R; Wottke, L; Artmann, R; Nagel, JM; Carranza, MO; Mayr, D; Rust, C; Fickert, P; Trauner, M; Gerbes, AL; Hohenester, S; Denk, GU
Role of interleukin-1 and its antagonism of hepatic stellate cell proliferation and liver fibrosis in the Abcb4(-/-) mouse model. World J Hepatol. 2016; 8(8):401-410
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Tang, Y; Fickert, P; Trauner, M; Marcus, N; Blomenkamp, K; Teckman, J
Autophagy induced by exogenous bile acids is therapeutic in a model of α-1-AT deficiency liver disease. Am J Physiol Gastrointest Liver Physiol. 2016; 311(1):G156-G165
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Rezania, S; Kammerer, S; Li, C; Steinecker-Frohnwieser, B; Gorischek, A; DeVaney, TT; Verheyen, S; Passegger, CA; Tabrizi-Wizsy, NG; Hackl, H; Platzer, D; Zarnani, AH; Malle, E; Jahn, SW; Bauernhofer, T; Schreibmayer, W
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Leis, HJ; Windischhofer, W
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Lipovšek, S; Novak, T; Janžekovič, F; Weiland, N; Leitinger, G
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Potočnjak, I; Degoricija, V; Trbušić, M; Terešak, SD; Radulović, B; Pregartner, G; Berghold, A; Tiran, B; Marsche, G; Frank, S
Metrics of High-Density Lipoprotein Function and Hospital Mortality in Acute Heart Failure Patients. PLoS One. 2016; 11(6):e0157507-e0157507
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Rogacev, KS; Heine, GH; Silbernagel, G; Kleber, ME; Seiler, S; Emrich, I; Lennartz, S; Werner, C; Zawada, AM; Fliser, D; Böhm, M; März, W; Scharnagl, H; Laufs, U
PCSK9 Plasma Concentrations Are Independent of GFR and Do Not Predict Cardiovascular Events in Patients with Decreased GFR. PLoS One. 2016; 11(1):e0146920-e0146920
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Vujic, N; Porter Abate, J; Schlager, S; David, T; Kratky, D; Koliwad, SK
Acyl-CoA:Diacylglycerol Acyltransferase 1 Expression Level in the Hematopoietic Compartment Impacts Inflammation in the Vascular Plaques of Atherosclerotic Mice. PLoS One. 2016; 11(5):e0156364-e0156364
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Klapper, M; Findeis, D; Koefeler, H; Döring, F
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Tiapko, O; Bacsa, B; de la Cruz, GG; Glasnov, T; Groschner, K
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März, W; Scharnagl, H; Gouni-Berthold, I; Silbernagel, G; Dressel, A; Grammer, TB; Landmesser, U; Dieplinger, H; Windler, E; Laufs, U
LDL-Cholesterol: Standards of Treatment 2016: A German Perspective. Am J Cardiovasc Drugs. 2016; 16(5):323-336
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Albrecht, C; Caniggia, I; Clifton, V; Göhner, C; Harris, L; Hemmings, D; Jawerbaum, A; Johnstone, E; Jones, H; Keelan, J; Lewis, R; Mitchell, M; Murthi, P; Powell, T; Saffery, R; Smith, R; Vaillancourt, C; Wadsack, C; Salomon, C
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Kessler, SM; Haybaeck, J; Kiemer, AK
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Triebl, A; Weissengruber, S; Trötzmüller, M; Lankmayr, E; Köfeler, H
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Thonhofer, M; Weber, P; Santana, AG; Fischer, R; Pabst, BM; Paschke, E; Schalli, M; Stütz, AE; Tschernutter, M; Windischhofer, W; Withers, SG
Synthesis of C-5a-chain extended derivatives of 4-epi-isofagomine: Powerful β-galactosidase inhibitors and low concentration activators of GM1-gangliosidosis-related human lysosomal β-galactosidase. Bioorg Med Chem Lett. 2016; 26(5):1438-1442
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Gaggl, M; Lajic, N; Heinze, G; Voigtländer, T; Sunder-Plassmann, R; Paschke, E; Fauler, G; Sunder-Plassmann, G; Mundigler, G
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Bodner, M; Vagalinski, B; Makarov, SE; Antic, DZ; Vujisic, LV; Leis, HJ; Raspotnig, G
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Alfakry, H; Malle, E; Koyani, CN; Pussinen, PJ; Sorsa, T
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Enko, D; Meinitzer, A; Mangge, H; Kriegshäuser, G; Halwachs-Baumann, G; Reininghaus, EZ; Bengesser, SA; Schnedl, WJ
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Thonhofer, M; Weber, P; Gonzalez Santana, A; Tysoe, C; Fischer, R; Pabst, BM; Paschke, E; Schalli, M; Stütz, AE; Tschernutter, M; Windischhofer, W; Withers, SG
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Rossberg, W; Saternus, R; Wagenpfeil, S; Kleber, M; März, W; Reichrath, S; Vogt, T; Reichrath, J
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Leis, HJ; Windischhofer, W
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Zöhrer, E; Resch, B; Scharnagl, H; Schlagenhauf, A; Fauler, G; Stojakovic, T; Hofer, N; Lang, U; Jahnel, J
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Herrera, E; Desoye, G
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2015

Silbernagel, G; Baumgartner, I; März, W
Mutations in NPC1L1 and coronary heart disease. N Engl J Med. 2015; 372(9):882-882
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Silbernagel, G; Baumgartner, I; März, W
Ezetimibe plus a Statin after Acute Coronary Syndromes. N Engl J Med. 2015; 373(15):1473-1473
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Exome sequencing identifies rare LDLR and APOA5 alleles conferring risk for myocardial infarction. NATURE. 2015; 518(7537): 102-106.
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New genetic loci link adipose and insulin biology to body fat distribution. Nature. 2015; 518(7538): 187-196.
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Hirschfield, GM; Mason, A; Luketic, V; Lindor, K; Gordon, SC; Mayo, M; Kowdley, KV; Vincent, C; Bodhenheimer, HC; Parés, A; Trauner, M; Marschall, HU; Adorini, L; Sciacca, C; Beecher-Jones, T; Castelloe, E; Böhm, O; Shapiro, D
Efficacy of obeticholic Acid in patients with primary biliary cirrhosis and inadequate response to ursodeoxycholic Acid. Gastroenterology. 2015; 148(4): 751-761.
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Silbernagel, G; Fauler, G; Genser, B; Drechsler, C; Krane, V; Scharnagl, H; Grammer, TB; Baumgartner, I; Ritz, E; Wanner, C; März, W
Intestinal cholesterol absorption, treatment with atorvastatin, and cardiovascular risk in hemodialysis patients. J Am Coll Cardiol. 2015; 65(21):2291-2298
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Grammer, TB; Kleber, ME; März, W; Silbernagel, G; Siekmeier, R; Wieland, H; Pilz, S; Tomaschitz, A; Koenig, W; Scharnagl, H
Low-density lipoprotein particle diameter and mortality: the Ludwigshafen Risk and Cardiovascular Health Study. Eur Heart J. 2015; 36(1):31-38
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Zewinger, S; Drechsler, C; Kleber, ME; Dressel, A; Riffel, J; Triem, S; Lehmann, M; Kopecky, C; Säemann, MD; Lepper, PM; Silbernagel, G; Scharnagl, H; Ritsch, A; Thorand, B; de las Heras Gala, T; Wagenpfeil, S; Koenig, W; Peters, A; Laufs, U; Wanner, C; Fliser, D; Speer, T; März, W
Serum amyloid A: high-density lipoproteins interaction and cardiovascular risk. Eur Heart J. 2015; 36(43):3007-3016
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Wooton-Kee, CR; Jain, AK; Wagner, M; Grusak, MA; Finegold, MJ; Lutsenko, S; Moore, DD
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Fasting-induced G0/G1 switch gene 2 and FGF21 expression in the liver are under regulation of adipose tissue derived fatty acids. J HEPATOL. 2015; 63(2): 437-445.
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Mueller, M; Thorell, A; Claudel, T; Jha, P; Koefeler, H; Lackner, C; Hoesel, B; Fauler, G; Stojakovic, T; Einarsson, C; Marschall, HU; Trauner, M
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Out, C; Patankar, JV; Doktorova, M; Boesjes, M; Bos, T; de Boer, S; Havinga, R; Wolters, H; Boverhof, R; van Dijk, TH; Smoczek, A; Bleich, A; Sachdev, V; Kratky, D; Kuipers, F; Verkade, HJ; Groen, AK
Gut microbiota inhibit Asbt-dependent intestinal bile acid reabsorption via Gata4. J Hepatol. 2015; 63(3): 697-704.
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Weinert, BT; Moustafa, T; Iesmantavicius, V; Zechner, R; Choudhary, C
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Bretscher, P; Egger, J; Shamshiev, A; Trotzmuller, M; Kofeler, H; Carreira, EM; Kopf, M; Freigang, S
Phospholipid oxidation generates potent anti-inflammatory lipid mediators that mimic structurally related pro-resolving eicosanoids by activating Nrf2. EMBO MOL MED. 2015; 7(5): 593-607.
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Landgraf, K; Rockstroh, D; Wagner, IV; Weise, S; Tauscher, R; Schwartze, JT; Löffler, D; Bühligen, U; Wojan, M; Till, H; Kratzsch, J; Kiess, W; Blüher, M; Körner, A
Evidence of early alterations in adipose tissue biology and function and its association with obesity-related inflammation and insulin resistance in children. Diabetes. 2015; 64(4): 1249-1261.
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Holzer, M; Schilcher, G; Curcic, S; Trieb, M; Ljubojevic, S; Stojakovic, T; Scharnagl, H; Kopecky, CM; Rosenkranz, AR; Heinemann, A; Marsche, G
Dialysis Modalities and HDL Composition and Function. J Am Soc Nephrol. 2015; 26(9): 2267-2276.
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Kopecky, C; Haidinger, M; Birner-Grünberger, R; Darnhofer, B; Kaltenecker, CC; Marsche, G; Holzer, M; Weichhart, T; Antlanger, M; Kovarik, JJ; Werzowa, J; Hecking, M; Säemann, MD
Restoration of Renal Function Does Not Correct Impairment of Uremic HDL Properties. J Am Soc Nephrol. 2015; 26(3): 565-575.
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Silbernagel, G; Genser, B; Drechsler, C; Scharnagl, H; Grammer, TB; Stojakovic, T; Krane, V; Ritz, E; Wanner, C; März, W
HDL cholesterol, apolipoproteins, and cardiovascular risk in hemodialysis patients. J Am Soc Nephrol. 2015; 26(2):484-492
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Bitter, A; Rümmele, P; Klein, K; Kandel, BA; Rieger, JK; Nüssler, AK; Zanger, UM; Trauner, M; Schwab, M; Burk, O
Pregnane X receptor activation and silencing promote steatosis of human hepatic cells by distinct lipogenic mechanisms. Arch Toxicol. 2015; 89(11): 2089-2103.
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Duschek, N; Stojakovic, T; Ghai, S; Strassegger, J; Basic, J; Scharnagl, H; Falkensammer, J; Huber, K; Assadian, A
Ratio of Apolipoprotein A-II/B Improves Risk Prediction of Postoperative Survival After Carotid Endarterectomy. Stroke. 2015; 46(6): 1700-1703.
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Degendorfer, G; Chuang, CY; Hammer, A; Malle, E; Davies, MJ
Peroxynitrous acid induces structural and functional modifications to basement membranes and its key component, laminin. Free Radic Biol Med. 2015; 89(12): 721-733.
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Birner-Gruenberger, R; Breinbauer, R
Weighing the proteasome for covalent modifications. Chem Biol. 2015; 22(3): 315-316.
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Laufs, U; Scharnagl, H; März, W
Statin intolerance. Curr Opin Lipidol. 2015; 26(6): 492-501.
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Hofmann, NA; Yang, J; Trauger, SA; Nakayama, H; Huang, L; Strunk, D; Moses, MA; Klagsbrun, M; Bischoff, J; Graier, WF
The GPR 55 agonist, L-α-lysophosphatidylinositol, mediates ovarian carcinoma cell-induced angiogenesis. Br J Pharmacol. 2015; 172(16): 4107-4118.
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Konya, V; Maric, J; Jandl, K; Luschnig, P; Aringer, I; Lanz, I; Platzer, W; Theiler, A; Bärnthaler, T; Frei, R; Marsche, G; Marsh, LM; Olschewski, A; Lippe, IT; Heinemann, A; Schuligoi, R
Activation of EP4 receptors prevents endotoxin-induced neutrophil infiltration into the airways and enhances microvascular barrier function. Br J Pharmacol. 2015; 96(8):
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Taschler, U; Eichmann, TO; Radner, FP; Grabner, GF; Wolinski, H; Storr, M; Lass, A; Schicho, R; Zimmermann, R
Monoglyceride lipase deficiency causes desensitization of intestinal cannabinoid receptor type 1 and increased colonic μ-opioid receptor sensitivity. Br J Pharmacol. 2015; 172(17): 4419-4429.
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Li, C; Rezania, S; Kammerer, S; Sokolowski, A; Devaney, T; Gorischek, A; Jahn, S; Hackl, H; Groschner, K; Windpassinger, C; Malle, E; Bauernhofer, T; Schreibmayer, W
Piezo1 forms mechanosensitive ion channels in the human MCF-7 breast cancer cell line. Sci Rep. 2015; 5:8364-8364
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Bernhart, E; Damm, S; Wintersperger, A; Nusshold, C; Brunner, AM; Plastira, I; Rechberger, G; Reicher, H; Wadsack, C; Zimmer, A; Malle, E; Sattler, W
Interference with distinct steps of sphingolipid synthesis and signaling attenuates proliferation of U87MG glioma cells. Biochem Pharmacol. 2015; 96(2): 119-130.
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Üllen, A; Nusshold, C; Glasnov, T; Saf, R; Cantillo, D; Eibinger, G; Reicher, H; Fauler, G; Bernhart, E; Hallstrom, S; Kogelnik, N; Zangger, K; Oliver Kappe, C; Malle, E; Sattler, W
Covalent adduct formation between the plasmalogen-derived modification product 2-chlorohexadecanal and phloretin. Biochem Pharmacol. 2015; 93(4): 470-481.
[Fulltext][PubMed]

Curcic, S; Holzer, M; Frei, R; Pasterk, L; Schicho, R; Heinemann, A; Marsche, G
Neutrophil effector responses are suppressed by secretory phospholipase A2 modified HDL. Biochim Biophys Acta. 2015; 1851(2): 184-193.
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Goeritzer, M; Vujic, N; Schlager, S; Chandak, PG; Korbelius, M; Gottschalk, B; Leopold, C; Obrowsky, S; Rainer, S; Doddapattar, P; Aflaki, E; Wegscheider, M; Sachdev, V; Graier, WF; Kolb, D; Radovic, B; Kratky, D
Active autophagy but not lipophagy in macrophages with defective lipolysis. Biochim Biophys Acta. 2015; 1851(10): 1304-1316.
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Taschler, U; Schreiber, R; Chitraju, C; Grabner, GF; Romauch, M; Wolinski, H; Haemmerle, G; Breinbauer, R; Zechner, R; Lass, A; Zimmermann, R
Adipose triglyceride lipase is involved in the mobilization of triglyceride and retinoid stores of hepatic stellate cells. Biochim Biophys Acta. 2015; 1851(7): 937-945.
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Wolinski, H; Hofbauer, HF; Hellauer, K; Cristobal-Sarramian, A; Kolb, D; Radulovic, M; Knittelfelder, OL; Rechberger, GN; Kohlwein, SD
Seipin is involved in the regulation of phosphatidic acid metabolism at a subdomain of the nuclear envelope in yeast. Biochim Biophys Acta. 2015; 1851(11): 1450-1464.
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Kopecky, C; Genser, B; Drechsler, C; Krane, V; Kaltenecker, CC; Hengstschlaeger, M; Marz, W; Wanner, C; Saemann, MD; Weichhart, T
Quantification of HDL Proteins, Cardiac Events, and Mortality in Patients with Type 2 Diabetes on Hemodialysis. CLIN J AM SOC NEPHRO. 2015; 10(2): 224-231.
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Parwani, AS; von Haehling, S; Kolodziejski, AI; Huemer, M; Wutzler, A; Attanasio, P; Stojakovic, T; Scharnagl, H; Haverkamp, W; Boldt, LH
Mid-regional proadrenomedullin levels predict recurrence of atrial fibrillation after catheter ablation. Int J Cardiol. 2015; 180(1): 129-133.
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Kassner, U; Salewsky, B; Wühle-Demuth, M; Szijarto, IA; Grenkowitz, T; Binner, P; März, W; Steinhagen-Thiessen, E; Demuth, I
Severe hypertriglyceridemia in a patient heterozygous for a lipoprotein lipase gene allele with two novel missense variants. EUR J HUM GENET. 2015; 23(9): 1259-1261.
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Sahu-Osen, A; Montero-Moran, G; Schittmayer, M; Fritz, K; Dinh, A; Chang, YF; McMahon, D; Boeszoermenyi, A; Cornaciu, I; Russell, D; Oberer, M; Carman, GM; Birner-Gruenberger, R; Brasaemle, DL
CGI-58/ABHD5 is phosphorylated on Ser239 by protein kinase A: control of subcellular localization. J Lipid Res. 2015; 56(1): 109-121.
[Fulltext][PubMed]

Marsche, G
Lp-PLA2, plaque inflammation and lesion development vary fundamentally between different vascular sites. J Am Heart Assoc. 2015; 4(2):
[Fulltext][PubMed]

Marsche, G
It s Time to Reassess the High-Density Lipoprotein (HDL) Hypothesis: CSL112, a Novel Promising Reconstituted HDL Formulation. J Am Heart Assoc. 2015; 4(8):e002371-e002371
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Heier, C; Radner, FP; Moustafa, T; Schreiber, R; Grond, S; Eichmann, TO; Schweiger, M; Schmidt, A; Cerk, IK; Oberer, M; Theussl, HC; Wojciechowski, J; Penninger, JM; Zimmermann, R; Zechner, R
G0/G1 Switch Gene 2 Regulates Cardiac Lipolysis. J Biol Chem. 2015; 290(43):26141-26150
[Fulltext][PubMed]

Pribasnig, MA; Mrak, I; Grabner, GF; Taschler, U; Knittelfelder, O; Scherz, B; Eichmann, TO; Heier, C; Grumet, L; Kowaliuk, J; Romauch, M; Holler, S; Anderl, F; Wolinski, H; Lass, A; Breinbauer, R; Marsche, G; Brown, JM; Zimmermann, R
α/β Hydrolase Domain-containing 6 (ABHD6) Degrades the Late Endosomal/Lysosomal Lipid Bis(monoacylglycero)phosphate. J Biol Chem. 2015; 290(50): 29869-29881.
[Fulltext][PubMed]

Sturm, EM; Parzmair, GP; Radnai, B; Frei, RB; Sturm, GJ; Hammer, A; Schuligoi, R; Lippe, IT; Heinemann, A
Phosphoinositide-dependent protein kinase 1 (PDK1) mediates potent inhibitory effects on eosinophils. Eur J Immunol. 2015; 45(5): 1548-1559.
[Fulltext][PubMed]

Schlager, S; Goeritzer, M; Jandl, K; Frei, R; Vujic, N; Kolb, D; Strohmaier, H; Dorow, J; Eichmann, TO; Rosenberger, A; Wölfler, A; Lass, A; Kershaw, EE; Ceglarek, U; Dichlberger, A; Heinemann, A; Kratky, D
Adipose triglyceride lipase acts on neutrophil lipid droplets to regulate substrate availability for lipid mediator synthesis. J Leukoc Biol. 2015; 98(5): 837-850.
[Fulltext][PubMed]

Aradska, J; Bulat, T; Sialana, FJ; Birner-Gruenberger, R; Erich, B; Lubec, G
Gel-free mass spectrometry analysis of Drosophila melanogaster heads. Proteomics. 2015; 15(19): 3356-3360.
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Brandenburg, VM; Kleber, ME; Vervloet, MG; Larsson, TE; Tomaschitz, A; Pilz, S; Stojakovic, T; Delgado, G; Grammer, TB; Marx, N; März, W; Scharnagl, H
Soluble klotho and mortality: The Ludwigshafen Risk and Cardiovascular Health Study. Atherosclerosis. 2015; 242(2):483-489
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Roier, S; Blume, T; Klug, L; Wagner, GE; Elhenawy, W; Zangger, K; Prassl, R; Reidl, J; Daum, G; Feldman, MF; Schild, S
A basis for vaccine development: Comparative characterization of Haemophilus influenzae outer membrane vesicles. Int J Med Microbiol. 2015; 305(3): 298-309.
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Laufs, U; Scharnagl, H; Halle, M; Windler, E; Endres, M; März, W
Treatment Options for Statin-Associated Muscle Symptoms. DTSCH ARZTEBL INT. 2015; 112(44): 748-755.
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Leitner, L; Schuch, K; Jürets, A; Itariu, BK; Keck, M; Grablowitz, V; Aszmann, OC; Prager, G; Staffler, G; Zeyda, M; Stulnig, TM
Immunological blockade of adipocyte inflammation caused by increased matrix metalloproteinase-cleaved osteopontin in obesity. Obesity (Silver Spring). 2015; 23(4): 779-785.
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Almer, G; Mangge, H; Zimmer, A; Prassl, R
Lipoprotein-Related and Apolipoprotein-Mediated Delivery Systems for Drug Targeting and Imaging. Curr Med Chem. 2015; 22(31): 3631-3651.
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Hartig, SM; Bader, DA; Abadie, KV; Motamed, M; Hamilton, MP; Long, W; York, B; Mueller, M; Wagner, M; Trauner, M; Chan, L; Bajaj, M; Moore, DD; Mancini, MA; McGuire, SE
Ubc9 Impairs Activation of the Brown Fat Energy Metabolism Program in Human White Adipocytes. Mol Endocrinol. 2015; 29(9): 1320-1333.
[Fulltext][PubMed]

Jain, P; Hassan, AM; Koyani, CN; Mayerhofer, R; Reichmann, F; Farzi, A; Schuligoi, R; Malle, E; Holzer, P
Behavioral and molecular processing of visceral pain in the brain of mice: impact of colitis and psychological stress. Front Behav Neurosci. 2015; 9(4):177-177
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Dawczynski, C; Kleber, ME; März, W; Jahreis, G; Lorkowski, S
Saturated fatty acids are not off the hook. NUTR METAB CARDIOVAS. 2015; 25(12): 1071-1078.
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Stančić, A; Jandl, K; Hasenöhrl, C; Reichmann, F; Marsche, G; Schuligoi, R; Heinemann, A; Storr, M; Schicho, R
The GPR55 antagonist CID16020046 protects against intestinal inflammation. Neurogastroenterol Motil. 2015; 27(10):1432-1445
[Fulltext][PubMed]

Das, SK; Stadelmeyer, E; Schauer, S; Schwarz, A; Strohmaier, H; Claudel, T; Zechner, R; Hoefler, G; Vesely, PW
Micro RNA-124a regulates lipolysis via adipose triglyceride lipase and comparative gene identification 58. Int J Mol Sci. 2015; 16(4):8555-8568
[Fulltext][PubMed]

Mangge, H; Prüller, F; Zelzer, S; Ainödhofer, H; Pailer, S; Kieslinger, P; Haybaeck, J; Obermayer-Pietsch, B; Cvirn, G; Gruber, HJ
Hypothyroidism Exacerbates Thrombophilia in Female Rats Fed with a High Fat Diet. Int J Mol Sci. 2015; 16(7):15776-15784
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Sala, P; Pötz, S; Brunner, M; Trötzmüller, M; Fauland, A; Triebl, A; Hartler, J; Lankmayr, E; Köfeler, HC
Determination of oxidized phosphatidylcholines by hydrophilic interaction liquid chromatography coupled to Fourier transform mass spectrometry. Int J Mol Sci. 2015; 16(4):8351-8363
[Fulltext][PubMed]

Zelzer, S; Mangge, H; Pailer, S; Ainoedhofer, H; Kieslinger, P; Stojakovic, T; Scharnagl, H; Prüller, F; Weghuber, D; Datz, C; Haybaeck, J; Obermayer-Pietsch, B; Trummer, C; Gostner, J; Gruber, HJ
Oxidized LDL Is Strictly Limited to Hyperthyroidism Irrespective of Fat Feeding in Female Sprague Dawley Rats. Int J Mol Sci. 2015; 16(5):11689-11698
[Fulltext][PubMed]

Kujala, M; Nevalainen, J; März, W; Laaksonen, R; Datta, S
Differential network analysis with multiply imputed lipidomic data. PLoS One. 2015; 10(3):e0121449-e0121449
[Fulltext][PubMed]

Neve, EPA; Kofeler, H; Hendriks, DFG; Nordling, A; Gogvadze, V; Mkrtchian, S; Naslund, E; Ingelman-Sundberg, M
Expression and Function of mARC: Roles in Lipogenesis and Metabolic Activation of Ximelagatran. PLOS ONE. 2015; 10(9): e0138487
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Rockstroh, D; Landgraf, K; Wagner, IV; Gesing, J; Tauscher, R; Lakowa, N; Kiess, W; Bühligen, U; Wojan, M; Till, H; Blüher, M; Körner, A
Direct evidence of brown adipocytes in different fat depots in children. PLoS One. 2015; 10(2):e0117841-e0117841
[Fulltext][PubMed]

Schneider, A; Schneider, MP; Krieter, DH; Genser, B; Scharnagl, H; Stojakovic, T; Wanner, C; Drechsler, C
Effect of High-Flux Dialysis on Circulating FGF-23 Levels in End-Stage Renal Disease Patients: Results from a Randomized Trial. PLoS One. 2015; 10(5):e0128079-e0128079
[Fulltext][PubMed]

Schicho, R; Marsche, G; Storr, M
Cardiovascular complications in inflammatory bowel disease. Curr Drug Targets. 2015; 16(3): 181-188.
[PubMed]

Jahnel, J; Zöhrer, E; Scharnagl, H; Erwa, W; Fauler, G; Stojakovic, T
Reference ranges of serum bile acids in children and adolescents. Clin Chem Lab Med. 2015; 53(11):1807-1813
[Fulltext][PubMed]

Buechel, HM; Stradner, MH; D Cruz, LM
Stages versus subsets: Invariant Natural Killer T cell lineage differentiation. Cytokine. 2015; 72(2): 204-209.
[Fulltext][PubMed]

Dražić, T; Sachdev, V; Leopold, C; Patankar, JV; Malnar, M; Hećimović, S; Levak-Frank, S; Habuš, I; Kratky, D
Synthesis and evaluation of novel amide amino-β-lactam derivatives as cholesterol absorption inhibitors. Bioorg Med Chem. 2015; 23(10): 2353-2359.
[Fulltext][PubMed]

Ramprecht, C; Jaritz, H; Streith, I; Zenzmaier, E; Köfeler, H; Hofmann-Wellenhof, R; Schaider, H; Hermetter, A
Toxicity of oxidized phosphatidylcholines in cultured human melanoma cells. CHEM PHYS LIPIDS. 2015; 189(9992): 39-47.
[Fulltext][PubMed]

Wultsch, A; Kaufmann, U; Ott, J; Stojakovic, T; Scharnagl, H; Stangl, H; Strobl, WM
Profound Changes in Sex Hormone Levels during Cross-Sex Hormone Therapy of Transsexuals do not Alter Serum Cholesterol Acceptor Capacity. J Sex Med. 2015; 12(6): 1436-1439.
[Fulltext][PubMed]

Koyani, CN; Flemmig, J; Malle, E; Arnhold, J
Myeloperoxidase scavenges peroxynitrite: A novel anti-inflammatory action of the heme enzyme. Arch Biochem Biophys. 2015; 571(4): 1-9.
[Fulltext][PubMed]

Falkensammer, J; Frech, A; Duschek, N; Gasteiger, S; Stojakovic, T; Scharnagl, H; Huber, K; Fraedrich, G; Greiner, A
Prognostic relevance of ischemia-modified albumin and NT-proBNP in patients with peripheral arterial occlusive disease. Clin Chim Acta. 2015; 438(1): 255-260.
[Fulltext][PubMed]

Adage, T; Konya, V; Weber, C; Strutzmann, E; Fuchs, T; Zankl, C; Gerlza, T; Jeremic, D; Heinemann, A; Kungl, AJ
Targeting glycosaminoglycans in the lung by an engineered CXCL8 as a novel therapeutic approach to lung inflammation. Eur J Pharmacol. 2015; 748C: 83-92.
[Fulltext][PubMed]

Meier, SM; Wultsch, A; Hollaus, M; Ammann, M; Pemberger, E; Liebscher, F; Lambers, B; Fruhwürth, S; Stojakovic, T; Scharnagl, H; Schmidt, A; Springer, A; Becker, J; Aufricht, C; Handisurya, A; Kapeller, S; Röhrl, C; Stangl, H; Strobl, W
Effect of chronic kidney disease on macrophage cholesterol efflux. Life Sci. 2015; 136(7): 1-6.
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Jahnel, J; Zöhrer, E; Alisi, A; Ferrari, F; Ceccarelli, S; De Vito, R; Scharnagl, H; Stojakovic, T; Fauler, G; Trauner, M; Nobili, V
Serum Bile Acid Levels in Children With Nonalcoholic Fatty Liver Disease. J Pediatr Gastroenterol Nutr. 2015; 61(1):85-90
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Gerlza, T; Winkler, S; Atlic, A; Zankl, C; Konya, V; Kitic, N; Strutzmann, E; Knebl, K; Adage, T; Heinemann, A; Weis, R; Kungl, AJ
Designing a mutant CCL2-HSA chimera with high glycosaminoglycan-binding affinity and selectivity. Protein Eng Des Sel. 2015; 28(8):231-240
[Fulltext][PubMed]

Tomazic, PV; Birner-Gruenberger, R; Leitner, A; Darnhofer, B; Spoerk, S; Lang-Loidolt, D
Apolipoproteins have a potential role in nasal mucus of allergic rhinitis patients: A proteomic study. Laryngoscope. 2015; 125(3): E91-E96.
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Kleber, ME; Siekmeier, R; Delgado, G; Grammer, TB; Winkelmann, BR; Scharnagl, H; Boehm, BO; März, W
C-reactive protein and lipoprotein-associated phospholipase A2 in smokers and nonsmokers of the ludwigshafen risk and cardiovascular health study. Adv Exp Med Biol. 2015; 832(12): 15-23.
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Schwerdtfeger, AR; Scharnagl, H; Stojakovic, T; Rathner, EM
Cognitive Avoidant Coping Is Associated with Higher Carotid Intima Media Thickness Among Middle-Aged Adults. Int J Behav Med. 2015; 22(5): 597-604.
[Fulltext][PubMed]

Brückner, A; Stabentheiner, E; Leis, HJ; Raspotnig, G
Chemical basis of unwettability in Liacaridae (Acari, Oribatida): specific variations of a cuticular acid/ester-based system. Exp Appl Acarol. 2015; 66(3): 313-335.
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Trauner, M; Halilbasic, E; Claudel, T; Steinacher, D; Fuchs, C; Moustafa, T; Pollheimer, M; Krones, E; Kienbacher, C; Traussnigg, S; Kazemi-Shirazi, L; Munda, P; Hofer, H; Fickert, P; Paumgartner, G
Potential of nor-Ursodeoxycholic Acid in Cholestatic and Metabolic Disorders. Dig Dis. 2015; 33(3):433-439
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Lipovšek, S; Novak, T; Janžekovič, F; Leitinger, G
Changes in the midgut diverticula in the harvestmen Amilenus aurantiacus (Phalangiidae, Opiliones) during winter diapause. Arthropod Struct Dev. 2015; 44(2): 131-141.
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Bokic, T; Storr, M; Schicho, R
Potential Causes and Present Pharmacotherapy of Irritable Bowel Syndrome: An Overview. Pharmacology. 2015; 96(1-2): 76-85.
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Pasterk, L; Philipose, S; Eller, K; Marsche, G; Heinemann, A; Schuligoi, R
The EP3 Agonist Sulprostone Enhances Platelet Adhesion But Not Thrombus Formation Under Flow Conditions. Pharmacology. 2015; 96(3-4): 137-143.
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Mirjanic-Azaric, B; Rizzo, M; Jurgens, G; Hallstroem, S; Srdic, S; Marc, J; Cerne, D
Atorvastatin treatment increases plasma bilirubin but not HMOX1 expression in stable angina patients. SCAND J CLIN LAB INV. 2015; 75(5): 382-389.
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Leis, HJ; Windischhofer, W
Molecular Characterisation of Group IVA (Cytosolic) Phospholipase A2 in Murine Osteoblastic MC3T3-E1 Cells. Protein J. 2015; 34(1): 29-34.
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Silbernagel, G; Baumgartner, I; März, W
Cardiovascular Safety of Plant Sterol and Stanol Consumption. J AOAC Int. 2015; 98(3):739-741
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Chennamsetty, I; Scharnagl, H; Kleber, ME; Marz, W; Kostner, GM
Lipoprotein(a): when to measure and how to treat?. LABORATORIUMSMEDIZIN. 2015; 39(2): 71-80.
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Izzo, AA; Muccioli, GG; Ruggieri, MR; Schicho, R
Endocannabinoids and the Digestive Tract and Bladder in Health and Disease. Handb Exp Pharmacol. 2015; 231: 423-447.
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Wruck, W; Kashofer, K; Rehman, S; Daskalaki, A; Berg, D; Gralka, E; Jozefczuk, J; Drews, K; Pandey, V; Regenbrecht, C; Wierling, C; Turano, P; Korf, U; Zatloukal, K; Lehrach, H; Westerhoff, HV; Adjaye, J
Multi-omic profiles of human non-alcoholic fatty liver disease tissue highlight heterogenic phenotypes. Sci Data. 2015; 2(12):150068-150068
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2014

Lee, JM; Wagner, M; Xiao, R; Kim, KH; Feng, D; Lazar, MA; Moore, DD
Nutrient-sensing nuclear receptors coordinate autophagy. Nature. 2014; 516(7529): 112-115.
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Demetz, E; Schroll, A; Auer, K; Heim, C; Patsch, JR; Eller, P; Theurl, M; Theurl, I; Theurl, M; Seifert, M; Lener, D; Stanzl, U; Haschka, D; Asshoff, M; Dichtl, S; Nairz, M; Huber, E; Stadlinger, M; Moschen, AR; Li, X; Pallweber, P; Scharnagl, H; Stojakovic, T; März, W; Kleber, ME; Garlaschelli, K; Uboldi, P; Catapano, AL; Stellaard, F; Rudling, M; Kuba, K; Imai, Y; Arita, M; Schuetz, JD; Pramstaller, PP; Tietge, UJ; Trauner, M; Norata, GD; Claudel, T; Hicks, AA; Weiss, G; Tancevski, I
The arachidonic acid metabolome serves as a conserved regulator of cholesterol metabolism. Cell Metab. 2014; 20(5):787-798
[Fulltext][PubMed]

Walter, KM; Schönenberger, MJ; Trötzmüller, M; Horn, M; Elsässer, HP; Moser, AB; Lucas, MS; Schwarz, T; Gerber, PA; Faust, PL; Moch, H; Köfeler, HC; Krek, W; Kovacs, WJ
Hif-2α promotes degradation of Mammalian peroxisomes by selective autophagy. CELL METAB. 2014; 20(5): 882-897.
[Fulltext][PubMed]

Ljubojevic, S; Radulovic, S; Leitinger, G; Sedej, S; Sacherer, M; Holzer, M; Winkler, C; Pritz, E; Mittler, T; Schmidt, A; Sereinigg, M; Wakula, P; Zissimopoulos, S; Bisping, E; Post, H; Marsche, G; Bossuyt, J; Bers, DM; Kockskämper, J; Pieske, B
Early remodeling of perinuclear Ca2+ stores and nucleoplasmic Ca2+ signaling during the development of hypertrophy and heart failure. Circulation. 2014; 130(3):244-255
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Scharnagl, H; Kleber, ME; März, W
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Kvaternik, H; Wanek, T; Hammerschmidt, F; Zolle, I; Aigner, R; Kuntner, C
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Scharnagl, H; Heuschneider, C; Sailer, S; Kleber, ME; März, W; Ritsch, A
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Abumaree, MH; Brownbill, P; Burton, G; Castillo, C; Chamley, L; Croy, BA; Drewlo, S; Dunk, C; Girard, S; Hansson, S; Jones, S; Jurisicova, A; Lewis, R; Letarte, M; Parast, M; Pehrson, C; Rappolee, D; Schneider, H; Tannetta, D; Varmuza, S; Wadsack, C; Wallace, AE; Zenerino, C; Lash, GE
IFPA Meeting 2013 Workshop Report III: maternal placental immunological interactions, novel determinants of trophoblast cell fate, dual ex vivo perfusion of the human placenta. Placenta. 2014; 35 Suppl(3):S15-S19
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Trauner, M; Halilbasic, E; Kazemi-Shirazi, L; Kienbacher, C; Staufer, K; Traussnigg, S; Hofer, H
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Raspotnig, G; Schaider, M; Stabentheiner, E; Leis, HJ; Karaman, I
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Schicho, R; Storr, M
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2013

Do, R; Willer, CJ; Schmidt, EM; Sengupta, S; Gao, C; Peloso, GM; Gustafsson, S; Kanoni, S; Ganna, A; Chen, J; Buchkovich, ML; Mora, S; Beckmann, JS; Bragg-Gresham, JL; Chang, HY; Demirkan, A; Den Hertog, HM; Donnelly, LA; Ehret, GB; Esko, T; Feitosa, MF; Ferreira, T; Fischer, K; Fontanillas, P; Fraser, RM; Freitag, DF; Gurdasani, D; Heikkilä, K; Hyppönen, E; Isaacs, A; Jackson, AU; Johansson, A; Johnson, T; Kaakinen, M; Kettunen, J; Kleber, ME; Li, X; Luan, J; Lyytikäinen, LP; Magnusson, PK; Mangino, M; Mihailov, E; Montasser, ME; Müller-Nurasyid, M; Nolte, IM; O Connell, JR; Palmer, CD; Perola, M; Petersen, AK; Sanna, S; Saxena, R; Service, SK; Shah, S; Shungin, D; Sidore, C; Song, C; Strawbridge, RJ; Surakka, I; Tanaka, T; Teslovich, TM; Thorleifsson, G; Van den Herik, EG; Voight, BF; Volcik, KA; Waite, LL; Wong, A; Wu, Y; Zhang, W; Absher, D; Asiki, G; Barroso, I; Been, LF; Bolton, JL; Bonnycastle, LL; Brambilla, P; Burnett, MS; Cesana, G; Dimitriou, M; Doney, AS; Döring, A; Elliott, P; Epstein, SE; Eyjolfsson, GI; Gigante, B; Goodarzi, MO; Grallert, H; Gravito, ML; Groves, CJ; Hallmans, G; Hartikainen, AL; Hayward, C; Hernandez, D; Hicks, AA; Holm, H; Hung, YJ; Illig, T; Jones, MR; Kaleebu, P; Kastelein, JJ; Khaw, KT; Kim, E; Klopp, N; Komulainen, P; Kumari, M; Langenberg, C; Lehtimäki, T; Lin, SY; Lindström, J; Loos, RJ; Mach, F; McArdle, WL; Meisinger, C; Mitchell, BD; Müller, G; Nagaraja, R; Narisu, N; Nieminen, TV; Nsubuga, RN; Olafsson, I; Ong, KK; Palotie, A; Papamarkou, T; Pomilla, C; Pouta, A; Rader, DJ; Reilly, MP; Ridker, PM; Rivadeneira, F; Rudan, I; Ruokonen, A; Samani, N; Scharnagl, H; Seeley, J; Silander, K; Stančáková, A; Stirrups, K; Swift, AJ; Tiret, L; Uitterlinden, AG; van Pelt, LJ; Vedantam, S; Wainwright, N; Wijmenga, C; Wild, SH; Willemsen, G; Wilsgaard, T; Wilson, JF; Young, EH; Zhao, JH; Adair, LS; Arveiler, D; Assimes, TL; Bandinelli, S; Bennett, F; Bochud, M; Boehm, BO; Boomsma, DI; Borecki, IB; Bornstein, SR; Bovet, P; Burnier, M; Campbell, H; Chakravarti, A; Chambers, JC; Chen, YD; Collins, FS; Cooper, RS; Danesh, J; Dedoussis, G; de Faire, U; Feranil, AB; Ferrières, J; Ferrucci, L; Freimer, NB; Gieger, C; Groop, LC; Gudnason, V; Gyllensten, U; Hamsten, A; Harris, TB; Hingorani, A; Hirschhorn, JN; Hofman, A; Hovingh, GK; Hsiung, CA; Humphries, SE; Hunt, SC; Hveem, K; Iribarren, C; Järvelin, MR; Jula, A; Kähönen, M; Kaprio, J; Kesäniemi, A; Kivimaki, M; Kooner, JS; Koudstaal, PJ; Krauss, RM; Kuh, D; Kuusisto, J; Kyvik, KO; Laakso, M; Lakka, TA; Lind, L; Lindgren, CM; Martin, NG; März, W; McCarthy, MI; McKenzie, CA; Meneton, P; Metspalu, A; Moilanen, L; Morris, AD; Munroe, PB; Njølstad, I; Pedersen, NL; Power, C; Pramstaller, PP; Price, JF; Psaty, BM; Quertermous, T; Rauramaa, R; Saleheen, D; Salomaa, V; Sanghera, DK; Saramies, J; Schwarz, PE; Sheu, WH; Shuldiner, AR; Siegbahn, A; Spector, TD; Stefansson, K; Strachan, DP; Tayo, BO; Tremoli, E; Tuomilehto, J; Uusitupa, M; van Duijn, CM; Vollenweider, P; Wallentin, L; Wareham, NJ; Whitfield, JB; Wolffenbuttel, BH; Altshuler, D; Ordovas, JM; Boerwinkle, E; Palmer, CN; Thorsteinsdottir, U; Chasman, DI; Rotter, JI; Franks, PW; Ripatti, S; Cupples, LA; Sandhu, MS; Rich, SS; Boehnke, M; Deloukas, P; Mohlke, KL; Ingelsson, E; Abecasis, GR; Daly, MJ; Neale, BM; Kathiresan, S
Common variants associated with plasma triglycerides and risk for coronary artery disease. Nat Genet. 2013; 45(11):1345-1352
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Global Lipids Genetics Consortium; Willer, CJ; Schmidt, EM; Sengupta, S; Peloso, GM; Gustafsson, S; Kanoni, S; Ganna, A; Chen, J; Buchkovich, ML; Mora, S; Beckmann, JS; Bragg-Gresham, JL; Chang, HY; Demirkan, A; Den Hertog, HM; Do, R; Donnelly, LA; Ehret, GB; Esko, T; Feitosa, MF; Ferreira, T; Fischer, K; Fontanillas, P; Fraser, RM; Freitag, DF; Gurdasani, D; Heikkilä, K; Hyppönen, E; Isaacs, A; Jackson, AU; Johansson, A; Johnson, T; Kaakinen, M; Kettunen, J; Kleber, ME; Li, X; Luan, J; Lyytikäinen, LP; Magnusson, PK; Mangino, M; Mihailov, E; Montasser, ME; Müller-Nurasyid, M; Nolte, IM; O Connell, JR; Palmer, CD; Perola, M; Petersen, AK; Sanna, S; Saxena, R; Service, SK; Shah, S; Shungin, D; Sidore, C; Song, C; Strawbridge, RJ; Surakka, I; Tanaka, T; Teslovich, TM; Thorleifsson, G; Van den Herik, EG; Voight, BF; Volcik, KA; Waite, LL; Wong, A; Wu, Y; Zhang, W; Absher, D; Asiki, G; Barroso, I; Been, LF; Bolton, JL; Bonnycastle, LL; Brambilla, P; Burnett, MS; Cesana, G; Dimitriou, M; Doney, AS; Döring, A; Elliott, P; Epstein, SE; Eyjolfsson, GI; Gigante, B; Goodarzi, MO; Grallert, H; Gravito, ML; Groves, CJ; Hallmans, G; Hartikainen, AL; Hayward, C; Hernandez, D; Hicks, AA; Holm, H; Hung, YJ; Illig, T; Jones, MR; Kaleebu, P; Kastelein, JJ; Khaw, KT; Kim, E; Klopp, N; Komulainen, P; Kumari, M; Langenberg, C; Lehtimäki, T; Lin, SY; Lindström, J; Loos, RJ; Mach, F; McArdle, WL; Meisinger, C; Mitchell, BD; Müller, G; Nagaraja, R; Narisu, N; Nieminen, TV; Nsubuga, RN; Olafsson, I; Ong, KK; Palotie, A; Papamarkou, T; Pomilla, C; Pouta, A; Rader, DJ; Reilly, MP; Ridker, PM; Rivadeneira, F; Rudan, I; Ruokonen, A; Samani, N; Scharnagl, H; Seeley, J; Silander, K; Stancáková, A; Stirrups, K; Swift, AJ; Tiret, L; Uitterlinden, AG; van Pelt, LJ; Vedantam, S; Wainwright, N; Wijmenga, C; Wild, SH; Willemsen, G; Wilsgaard, T; Wilson, JF; Young, EH; Zhao, JH; Adair, LS; Arveiler, D; Assimes, TL; Bandinelli, S; Bennett, F; Bochud, M; Boehm, BO; Boomsma, DI; Borecki, IB; Bornstein, SR; Bovet, P; Burnier, M; Campbell, H; Chakravarti, A; Chambers, JC; Chen, YD; Collins, FS; Cooper, RS; Danesh, J; Dedoussis, G; de Faire, U; Feranil, AB; Ferrières, J; Ferrucci, L; Freimer, NB; Gieger, C; Groop, LC; Gudnason, V; Gyllensten, U; Hamsten, A; Harris, TB; Hingorani, A; Hirschhorn, JN; Hofman, A; Hovingh, GK; Hsiung, CA; Humphries, SE; Hunt, SC; Hveem, K; Iribarren, C; Järvelin, MR; Jula, A; Kähönen, M; Kaprio, J; Kesäniemi, A; Kivimaki, M; Kooner, JS; Koudstaal, PJ; Krauss, RM; Kuh, D; Kuusisto, J; Kyvik, KO; Laakso, M; Lakka, TA; Lind, L; Lindgren, CM; Martin, NG; März, W; McCarthy, MI; McKenzie, CA; Meneton, P; Metspalu, A; Moilanen, L; Morris, AD; Munroe, PB; Njølstad, I; Pedersen, NL; Power, C; Pramstaller, PP; Price, JF; Psaty, BM; Quertermous, T; Rauramaa, R; Saleheen, D; Salomaa, V; Sanghera, DK; Saramies, J; Schwarz, PE; Sheu, WH; Shuldiner, AR; Siegbahn, A; Spector, TD; Stefansson, K; Strachan, DP; Tayo, BO; Tremoli, E; Tuomilehto, J; Uusitupa, M; van Duijn, CM; Vollenweider, P; Wallentin, L; Wareham, NJ; Whitfield, JB; Wolffenbuttel, BH; Ordovas, JM; Boerwinkle, E; Palmer, CN; Thorsteinsdottir, U; Chasman, DI; Rotter, JI; Franks, PW; Ripatti, S; Cupples, LA; Sandhu, MS; Rich, SS; Boehnke, M; Deloukas, P; Kathiresan, S; Mohlke, KL; Ingelsson, E; Abecasis, GR
Discovery and refinement of loci associated with lipid levels. Nat Genet. 2013; 45(11):1274-1283
[Fulltext][PubMed]

Silbernagel, G; Chapman, MJ; Genser, B; Kleber, ME; Fauler, G; Scharnagl, H; Grammer, TB; Boehm, BO; Mäkelä, KM; Kähönen, M; Carmena, R; Rietzschel, ER; Bruckert, E; Deanfield, JE; Miettinen, TA; Raitakari, OT; Lehtimäki, T; März, W
High intestinal cholesterol absorption is associated with cardiovascular disease and risk alleles in ABCG8 and ABO: evidence from the LURIC and YFS cohorts and from a meta-analysis. J Am Coll Cardiol. 2013; 62(4):291-299
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Leebmann, J; Roeseler, E; Julius, U; Heigl, F; Spitthoever, R; Heutling, D; Breitenberger, P; Maerz, W; Lehmacher, W; Heibges, A; Klingel, R; Pro(a)LiFe Study Group*
Lipoprotein apheresis in patients with maximally tolerated lipid-lowering therapy, lipoprotein(a)-hyperlipoproteinemia, and progressive cardiovascular disease: prospective observational multicenter study. Circulation. 2013; 128(24):2567-2576
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Sabater-Lleal, M; Huang, J; Chasman, D; Naitza, S; Dehghan, A; Johnson, AD; Teumer, A; Reiner, AP; Folkersen, L; Basu, S; Rudnicka, AR; Trompet, S; Mälarstig, A; Baumert, J; Bis, JC; Guo, X; Hottenga, JJ; Shin, SY; Lopez, LM; Lahti, J; Tanaka, T; Yanek, LR; Oudot-Mellakh, T; Wilson, JF; Navarro, P; Huffman, JE; Zemunik, T; Redline, S; Mehra, R; Pulanic, D; Rudan, I; Wright, AF; Kolcic, I; Polasek, O; Wild, SH; Campbell, H; Curb, JD; Wallace, R; Liu, S; Eaton, CB; Becker, DM; Becker, LC; Bandinelli, S; Räikkönen, K; Widen, E; Palotie, A; Fornage, M; Green, D; Gross, M; Davies, G; Harris, SE; Liewald, DC; Starr, JM; Williams, FM; Grant, PJ; Spector, TD; Strawbridge, RJ; Silveira, A; Sennblad, B; Rivadeneira, F; Uitterlinden, AG; Franco, OH; Hofman, A; van Dongen, J; Willemsen, G; Boomsma, DI; Yao, J; Swords Jenny, N; Haritunians, T; McKnight, B; Lumley, T; Taylor, KD; Rotter, JI; Psaty, BM; Peters, A; Gieger, C; Illig, T; Grotevendt, A; Homuth, G; Völzke, H; Kocher, T; Goel, A; Franzosi, MG; Seedorf, U; Clarke, R; Steri, M; Tarasov, KV; Sanna, S; Schlessinger, D; Stott, DJ; Sattar, N; Buckley, BM; Rumley, A; Lowe, GD; McArdle, WL; Chen, MH; Tofler, GH; Song, J; Boerwinkle, E; Folsom, AR; Rose, LM; Franco-Cereceda, A; Teichert, M; Ikram, MA; Mosley, TH; Bevan, S; Dichgans, M; Rothwell, PM; Sudlow, CL; Hopewell, JC; Chambers, JC; Saleheen, D; Kooner, JS; Danesh, J; Nelson, CP; Erdmann, J; Reilly, MP; Kathiresan, S; Schunkert, H; Morange, PE; Ferrucci, L; Eriksson, JG; Jacobs, D; Deary, IJ; Soranzo, N; Witteman, JC; de Geus, EJ; Tracy, RP; Hayward, C; Koenig, W; Cucca, F; Jukema, JW; Eriksson, P; Seshadri, S; Markus, HS; Watkins, H; Samani, NJ; VTE Consortium; STROKE Consortium; Wellcome Trust Case Control Consortium 2 (WTCCC2); C4D Consortium; CARDIoGRAM Consortium; Wallaschofski, H; Smith, NL; Tregouet, D; Ridker, PM; Tang, W; Strachan, DP; Hamsten, A; O Donnell, CJ
Multiethnic meta-analysis of genome-wide association studies in >100 000 subjects identifies 23 fibrinogen-associated Loci but no strong evidence of a causal association between circulating fibrinogen and cardiovascular disease. Circulation. 2013; 128(12):1310-1324
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Grammer, TB; Hoffmann, MM; Scharnagl, H; Kleber, ME; Silbernagel, G; Pilz, S; Tomaschitz, A; Lerchbaum, E; Siekmeier, R; März, W
Smoking, apolipoprotein E genotypes, and mortality (the Ludwigshafen RIsk and Cardiovascular Health study). Eur Heart J. 2013; 34(17):1298-1305
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Kostner, KM; März, W; Kostner, GM
When should we measure lipoprotein (a)?. Eur Heart J. 2013; 34(42):3268-3276
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Silbernagel, G; Schöttker, B; Appelbaum, S; Scharnagl, H; Kleber, ME; Grammer, TB; Ritsch, A; Mons, U; Holleczek, B; Goliasch, G; Niessner, A; Boehm, BO; Schnabel, RB; Brenner, H; Blankenberg, S; Landmesser, U; März, W
High-density lipoprotein cholesterol, coronary artery disease, and cardiovascular mortality. Eur Heart J. 2013; 34(46):3563-3571
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Ho, JE; Chen, WY; Chen, MH; Larson, MG; McCabe, EL; Cheng, S; Ghorbani, A; Coglianese, E; Emilsson, V; Johnson, AD; Walter, S; Franceschini, N; O Donnell, CJ; CARDIoGRAM Consortium; CHARGE Inflammation Working Group; Dehghan, A; Lu, C; Levy, D; Newton-Cheh, C; CHARGE Heart Failure Working Group; Lin, H; Felix, JF; Schreiter, ER; Vasan, RS; Januzzi, JL; Lee, RT; Wang, TJ; Assimes, TL; Deloukas, P; Erdmann, J; Holm, H; Kathiresan, S; König, IR; McPherson, R; Reilly, MP; Roberts, R; Samani, NJ; Schunkert, H; Stewart, AF
Common genetic variation at the IL1RL1 locus regulates IL-33/ST2 signaling. J Clin Invest. 2013; 123(10): 4208-4218.
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Mayer, N; Schweiger, M; Romauch, M; Grabner, GF; Eichmann, TO; Fuchs, E; Ivkovic, J; Heier, C; Mrak, I; Lass, A; Höfler, G; Fledelius, C; Zechner, R; Zimmermann, R; Breinbauer, R
Development of small-molecule inhibitors targeting adipose triglyceride lipase. Nat Chem Biol. 2013; 9(12):785-787
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Konya, V; Üllen, A; Kampitsch, N; Theiler, A; Philipose, S; Parzmair, GP; Marsche, G; Peskar, BA; Schuligoi, R; Sattler, W; Heinemann, A
Endothelial E-type prostanoid 4 receptors promote barrier function and inhibit neutrophil trafficking. J Allergy Clin Immunol. 2013; 131(2):532-40.e1-532-40.e2
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Patankar, JV; Sachdev, V; Obrowsky, S; Levak-Frank, S; Kratky, D
Intestinal GATA4 deficiency induces proximal fibroblast growth factor 15 expression and represses hepatic gluconeogenesis. J Hepatol. 2013; 59(5):1147-1149
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Das, SK; Hoefler, G
The role of triglyceride lipases in cancer associated cachexia. Trends Mol Med. 2013; 19(5):292-301
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Stradner, MH; Gruber, G; Angerer, H; Huber, V; Setznagl, D; Kremser, ML; Moazedi-Fürst, FC; Windhager, R; Graninger, WB
Sphingosine 1-phosphate counteracts the effects of interleukin-1β in human chondrocytes. Arthritis Rheum. 2013; 65(8):2113-2122
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Konya, V; Marsche, G; Schuligoi, R; Heinemann, A
E-type prostanoid receptor 4 (EP4) in disease and therapy. Pharmacol Ther. 2013; 138(3):485-502
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Marsche, G; Saemann, MD; Heinemann, A; Holzer, M
Inflammation alters HDL composition and function: Implications for HDL-raising therapies. Pharmacol Ther. 2013; 137(3):341-351
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Lieb, W; Jansen, H; Loley, C; Pencina, MJ; Nelson, CP; Newton-Cheh, C; Kathiresan, S; Reilly, MP; Assimes, TL; Boerwinkle, E; Hall, AS; Hengstenberg, C; Laaksonen, R; McPherson, R; Thorsteinsdottir, U; Ziegler, A; Peters, A; Thompson, JR; König, IR; Erdmann, J; Samani, NJ; Vasan, RS; Schunkert, H; CARDIoGRAM; Assimes, TL; Deloukas, P; Erdmann, J; Holm, H; Kathiresan, S; König, IR; McPherson, R; Reilly, MP; Roberts, R; Samani, NJ; Schunkert, H; Stewart, AF
Genetic predisposition to higher blood pressure increases coronary artery disease risk. Hypertension. 2013; 61(5):995-1001
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Gradauer, K; Barthelmes, J; Vonach, C; Almer, G; Mangge, H; Teubl, B; Roblegg, E; Dünnhaupt, S; Fröhlich, E; Bernkop-Schnürch, A; Prassl, R
Liposomes coated with thiolated chitosan enhance oral peptide delivery to rats. J Control Release. 2013; 172(3):872-878
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Gradauer, K; Dünnhaupt, S; Vonach, C; Szöllösi, H; Pali-Schöll, I; Mangge, H; Jensen-Jarolim, E; Bernkop-Schnürch, A; Prassl, R
Thiomer-coated liposomes harbor permeation enhancing and efflux pump inhibitory properties. J Control Release. 2013; 165(3):207-215
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Thomas, G; Betters, JL; Lord, CC; Brown, AL; Marshall, S; Ferguson, D; Sawyer, J; Davis, MA; Melchior, JT; Blume, LC; Howlett, AC; Ivanova, PT; Milne, SB; Myers, DS; Mrak, I; Leber, V; Heier, C; Taschler, U; Blankman, JL; Cravatt, BF; Lee, RG; Crooke, RM; Graham, MJ; Zimmermann, R; Brown, HA; Brown, JM
The serine hydrolase ABHD6 Is a critical regulator of the metabolic syndrome. Cell Rep. 2013; 5(2):508-520
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Pabst, M; Fischl, RM; Brecker, L; Morelle, W; Fauland, A; Köfeler, H; Altmann, F; Léonard, R
Rhamnogalacturonan II structure shows variation in the side chains monosaccharide composition and methylation status within and across different plant species. Plant J. 2013; 76(1):61-72
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Reiner, AP; Hartiala, J; Zeller, T; Bis, JC; Dupuis, J; Fornage, M; Baumert, J; Kleber, ME; Wild, PS; Baldus, S; Bielinski, SJ; Fontes, JD; Illig, T; Keating, BJ; Lange, LA; Ojeda, F; Müller-Nurasyid, M; Munzel, TF; Psaty, BM; Rice, K; Rotter, JI; Schnabel, RB; Tang, WH; Thorand, B; Erdmann, J; CARDIoGRAM Consortium; Jacobs, DR; Wilson, JG; Koenig, W; Tracy, RP; Blankenberg, S; März, W; Gross, MD; Benjamin, EJ; Hazen, SL; Allayee, H
Genome-wide and gene-centric analyses of circulating myeloperoxidase levels in the charge and care consortia. Hum Mol Genet. 2013; 22(16):3381-3393
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Finkenstedt, A; Auer, C; Glodny, B; Posch, U; Steitzer, H; Lanzer, G; Pratschke, J; Biebl, M; Steurer, M; Graziadei, I; Vogel, W; Zoller, H
Patatin-like phospholipase domain-containing protein 3 rs738409-G in recipients of liver transplants is a risk factor for graft steatosis. Clin Gastroenterol Hepatol. 2013; 11(12):1667-1672
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Hartler, J; Tharakan, R; Köfeler, HC; Graham, DR; Thallinger, GG
Bioinformatics tools and challenges in structural analysis of lipidomics MS/MS data. Brief Bioinform. 2013; 14(3):375-390
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Silbernagel, G; Genser, B; Nestel, P; März, W
Plant sterols and atherosclerosis. Curr Opin Lipidol. 2013; 24(1):12-17
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Binder, V; Ljubojevic, S; Haybaeck, J; Holzer, M; El-Gamal, D; Schicho, R; Pieske, B; Heinemann, A; Marsche, G
The myeloperoxidase product hypochlorous acid generates irreversible high-density lipoprotein receptor inhibitors. Arterioscler Thromb Vasc Biol. 2013; 33(5):1020-1027
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Robert, J; Lehner, M; Frank, S; Perisa, D; von Eckardstein, A; Rohrer, L
Interleukin 6 stimulates endothelial binding and transport of high-density lipoprotein through induction of endothelial lipase. Arterioscler Thromb Vasc Biol. 2013; 33(12):2699-2706
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Makela, KM; Seppala, I; Hernesniemi, JA; Lyytikainen, LP; Oksala, N; Kleber, ME; Scharnagl, H; Grammer, TB; Baumert, J; Thorand, B; Jula, A; Hutri-Kahonen, N; Juonala, M; Laitinen, T; Laaksonen, R; Karhunen, PJ; Nikus, KC; Nieminen, T; Laurikka, J; Kuukasjarvi, P; Tarkka, M; Viik, J; Klopp, N; Illig, T; Kettunen, J; Ahotupa, M; Viikari, JSA; Kahonen, M; Raitakari, OT; Karakas, M; Koenig, W; Boehm, BO; Winkelmann, BR; Marz, W; Lehtimaki, T;
Genome-Wide Association Study Pinpoints a New Functional Apolipoprotein B Variant Influencing Oxidized Low-Density Lipoprotein Levels But Not Cardiovascular Events AtheroRemo Consortium. Circ Cardiovasc Genet. 2013; 6(1):73-81
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Fuchs, C; Claudel, T; Trauner, M
Bile acid-mediated control of liver triglycerides. Semin Liver Dis. 2013; 33(4):330-342
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Wang, J; Sun, Y; Zheng, S; Zhang, XS; Zhou, H; Chen, L
APG: an Active Protein-Gene network model to quantify regulatory signals in complex biological systems. Sci Rep. 2013; 3(3): 1097-1097.
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Zhang, X; González-Cobos, JC; Schindl, R; Muik, M; Ruhle, B; Motiani, RK; Bisaillon, JM; Zhang, W; Fahrner, M; Barroso, M; Matrougui, K; Romanin, C; Trebak, M
Mechanisms of STIM1 activation of store-independent leukotriene C4-regulated Ca2+ channels. Mol Cell Biol. 2013; 33(18): 3715-3723.
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Carmona-Gutierrez, D; Alavian-Ghavanini, A; Habernig, L; Bauer, MA; Hammer, A; Rossmann, C; Zimmermann, AS; Ruckenstuhl, C; Büttner, S; Eisenberg, T; Sattler, W; Malle, E; Madeo, F
The cell death protease Kex1p is essential for hypochlorite-induced apoptosis in yeast. Cell Cycle. 2013; 12(11):1704-1712
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Schmidt, JA; Bell, FM; Akam, E; Marshall, C; Dainty, IA; Heinemann, A; Dougall, IG; Bonnert, RV; Sargent, CA
Biochemical and pharmacological characterization of AZD1981, an orally available selective DP2 antagonist in clinical development for asthma. Br J Pharmacol. 2013; 168(7):1626-1638
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Doddapattar, P; Radović, B; Patankar, JV; Obrowsky, S; Jandl, K; Nusshold, C; Kolb, D; Vujić, N; Doshi, L; Chandak, PG; Goeritzer, M; Ahammer, H; Hoefler, G; Sattler, W; Kratky, D
Xanthohumol ameliorates atherosclerotic plaque formation, hypercholesterolemia, and hepatic steatosis in ApoE-deficient mice. Mol Nutr Food Res. 2013; 57(10):1718-1728
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Li, K; Fichna, J; Schicho, R; Saur, D; Bashashati, M; Mackie, K; Li, Y; Zimmer, A; Göke, B; Sharkey, KA; Storr, M
A role for O-1602 and G protein-coupled receptor GPR55 in the control of colonic motility in mice. Neuropharmacology. 2013; 71(3):255-263
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Kargl, J; Haybaeck, J; Stančić, A; Andersen, L; Marsche, G; Heinemann, A; Schicho, R
O-1602, an atypical cannabinoid, inhibits tumor growth in colitis-associated colon cancer through multiple mechanisms. J Mol Med (Berl). 2013; 91(4):449-458
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Chitraju, C; Trötzmüller, M; Hartler, J; Wolinski, H; Thallinger, GG; Haemmerle, G; Zechner, R; Zimmermann, R; Köfeler, HC; Spener, F
The impact of genetic stress by ATGL deficiency on the lipidome of lipid droplets from murine hepatocytes. J Lipid Res. 2013; 54(8):2185-2194
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Liebisch, G; Vizcaíno, JA; Köfeler, H; Trötzmüller, M; Griffiths, WJ; Schmitz, G; Spener, F; Wakelam, MJ
Shorthand notation for lipid structures derived from mass spectrometry. J Lipid Res. 2013; 54(6):1523-1530
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Obrowsky, S; Chandak, PG; Patankar, JV; Povoden, S; Schlager, S; Kershaw, EE; Bogner-Strauss, JG; Hoefler, G; Levak-Frank, S; Kratky, D
Adipose triglyceride lipase is a TG hydrolase of the small intestine and regulates intestinal PPARα signaling. J Lipid Res. 2013; 54(2):425-435
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Pollak, NM; Schweiger, M; Jaeger, D; Kolb, D; Kumari, M; Schreiber, R; Kolleritsch, S; Markolin, P; Grabner, GF; Heier, C; Zierler, KA; Rülicke, T; Zimmermann, R; Lass, A; Zechner, R; Haemmerle, G
Cardiac-specific overexpression of perilipin 5 provokes severe cardiac steatosis via the formation of a lipolytic barrier. J Lipid Res. 2013; 54(4):1092-1102
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Kiss, E; Kränzlin, B; Wagenblaβ, K; Bonrouhi, M; Thiery, J; Gröne, E; Nordström, V; Teupser, D; Gretz, N; Malle, E; Gröne, HJ
Lipid droplet accumulation is associated with an increase in hyperglycemia-induced renal damage: prevention by liver X receptors. Am J Pathol. 2013; 182(3):727-741
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Bauer, R; Plieschnig, JA; Finkes, T; Riegler, B; Hermann, M; Schneider, WJ
The developing chicken yolk sac acquires nutrient transport competence by an orchestrated differentiation process of its endodermal epithelial cells. J Biol Chem. 2013; 288(2): 1088-1098.
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Pessentheiner, AR; Pelzmann, HJ; Walenta, E; Schweiger, M; Groschner, LN; Graier, WF; Kolb, D; Uno, K; Miyazaki, T; Nitta, A; Rieder, D; Prokesch, A; Bogner-Strauss, JG
NAT8L (N-acetyltransferase 8-like) accelerates lipid turnover and increases energy expenditure in brown adipocytes. J Biol Chem. 2013; 288(50):36040-36051
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Rengachari, S; Aschauer, P; Schittmayer, M; Mayer, N; Gruber, K; Breinbauer, R; Birner-Gruenberger, R; Dreveny, I; Oberer, M
Conformational plasticity and ligand binding of bacterial monoacylglycerol lipase. J Biol Chem. 2013; 288(43):31093-31104
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Zierler, KA; Jaeger, D; Pollak, NM; Eder, S; Rechberger, GN; Radner, FP; Woelkart, G; Kolb, D; Schmidt, A; Kumari, M; Preiss-Landl, K; Pieske, B; Mayer, B; Zimmermann, R; Lass, A; Zechner, R; Haemmerle, G
Functional cardiac lipolysis in mice critically depends on comparative gene identification-58. J Biol Chem. 2013; 288(14):9892-9904
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Beranger, GE; Karbiener, M; Barquissau, V; Pisani, DF; Scheideler, M; Langin, D; Amri, EZ
In vitro brown and "brite"/"beige" adipogenesis: human cellular models and molecular aspects. BBA-MOL CELL BIOL L. 2013; 1831(5): 905-914.
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Holzer, M; Trieb, M; Konya, V; Wadsack, C; Heinemann, A; Marsche, G
Aging affects high-density lipoprotein composition and function. Biochim Biophys Acta. 2013; 1831(9):1442-1448
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Huang, J; Das, SK; Jha, P; Al Zoughbi, W; Schauer, S; Claudel, T; Sexl, V; Vesely, P; Birner-Gruenberger, R; Kratky, D; Trauner, M; Hoefler, G
The PPARα agonist fenofibrate suppresses B-cell lymphoma in mice by modulating lipid metabolism. Biochim Biophys Acta. 2013; 1831(10):1555-1565
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Ivashov, VA; Grillitsch, K; Koefeler, H; Leitner, E; Baeumlisberger, D; Karas, M; Daum, G
Lipidome and proteome of lipid droplets from the methylotrophic yeast Pichia pastoris. Biochim Biophys Acta. 2013; 1831(2):282-290
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Nusshold, C; Uellen, A; Bernhart, E; Hammer, A; Damm, S; Wintersperger, A; Reicher, H; Hermetter, A; Malle, E; Sattler, W
Endocytosis and intracellular processing of BODIPY-sphingomyelin by murine CATH.a neurons. Biochim Biophys Acta. 2013; 1831(12):1665-1678
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Sreckovic, I; Birner-Gruenberger, R; Obrist, B; Stojakovic, T; Scharnagl, H; Holzer, M; Scholler, M; Philipose, S; Marsche, G; Lang, U; Desoye, G; Wadsack, C
Distinct composition of human fetal HDL attenuates its anti-oxidative capacity. Biochim Biophys Acta. 2013; 1831(4):737-746
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Lu, J; Roth, RA; Malle, E; Ganey, PE
Roles of the hemostatic system and neutrophils in liver injury from co-exposure to amiodarone and lipopolysaccharide. Toxicol Sci. 2013; 136(1):51-62
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Yu, A; Zheng, Y; Zhang, R; Huang, J; Zhu, Z; Zhou, R; Jin, D; Yang, Z
Resistin impairs SIRT1 function and induces senescence-associated phenotype in hepatocytes. Mol Cell Endocrinol. 2013; 377(1-2):23-32
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Duszka, K; Bogner-Strauss, JG; Hackl, H; Rieder, D; Neuhold, C; Prokesch, A; Trajanoski, Z; Krogsdam, AM
Nr4a1 is required for fasting-induced down-regulation of Pparγ2 in white adipose tissue. Mol Endocrinol. 2013; 27(1): 135-149.
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Schupp, M; Chen, F; Briggs, ER; Rao, S; Pelzmann, HJ; Pessentheiner, AR; Bogner-Strauss, JG; Lazar, MA; Baldwin, D; Prokesch, A
Metabolite and transcriptome analysis during fasting suggest a role for the p53-Ddit4 axis in major metabolic tissues. BMC Genomics. 2013; 14(11):758-758
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Costet, P; Ehrenborg, E; Fisher, R; Fielding, B; Groen, A; Kardassis, D; Malle, E; Mulder, M; Niemeier, A; Norata, GD; Hansen, AT; Eckardstein, AV
European Lipoprotein Club: Report of the 35th ELC Annual Conference (Tutzing, 10th-13th September 2012). Atherosclerosis. 2013; 226(2):510-516
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Dastani, Z; Johnson, T; Kronenberg, F; Nelson, CP; Assimes, TL; März, W; CARDIoGRAM Consortium; ADIPOGen Consortium; Richards, JB
The shared allelic architecture of adiponectin levels and coronary artery disease. Atherosclerosis. 2013; 229(1):145-148
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Knebel, B; Kotzka, J; Lehr, S; Hartwig, S; Avci, H; Jacob, S; Nitzgen, U; Schiller, M; März, W; Hoffmann, MM; Seemanova, E; Haas, J; Muller-Wieland, D
A mutation in the c-fos gene associated with congenital generalized lipodystrophy. Orphanet J Rare Dis. 2013; 8(8):119-119
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Kargl, J; Brown, AJ; Andersen, L; Dorn, G; Schicho, R; Waldhoer, M; Heinemann, A
A selective antagonist reveals a potential role of G protein-coupled receptor 55 in platelet and endothelial cell function. J Pharmacol Exp Ther. 2013; 346(1):54-66
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Storr, M; Vogel, HJ; Schicho, R
Metabolomics: is it useful for inflammatory bowel diseases?. Curr Opin Gastroenterol. 2013; 29(4):378-383
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Blüher, S; Raschpichler, M; Hirsch, W; Till, H
A case report and review of the literature of laparoscopic sleeve gastrectomy in morbidly obese adolescents: Beyond metabolic surgery and visceral fat reduction. Metabolism. 2013; 62(6):761-767
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Halasiddappa, LM; Koefeler, H; Futerman, AH; Hermetter, A
Oxidized phospholipids induce ceramide accumulation in RAW 264.7 macrophages: role of ceramide synthases. PLoS One. 2013; 8(7):e70002-e70002
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Nikam, A; Patankar, JV; Lackner, C; Schöck, E; Kratky, D; Zatloukal, K; Abuja, PM
Transition between acute and chronic hepatotoxicity in mice is associated with impaired energy metabolism and induction of mitochondrial heme oxygenase-1. PLoS One. 2013; 8(6):e66094-e66094
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Oberbach, A; Jehmlich, N; Schlichting, N; Heinrich, M; Lehmann, S; Wirth, H; Till, H; Stolzenburg, JU; Völker, U; Adams, V; Neuhaus, J
Molecular fingerprint of high fat diet induced urinary bladder metabolic dysfunction in a rat model. PLoS One. 2013; 8(6):e66636-e66636
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Rao, SP; Riederer, M; Lechleitner, M; Hermansson, M; Desoye, G; Hallström, S; Graier, WF; Frank, S
Acyl chain-dependent effect of lysophosphatidylcholine on endothelium-dependent vasorelaxation. PLoS One. 2013; 8(5):e65155-e65155
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Üllen, A; Singewald, E; Konya, V; Fauler, G; Reicher, H; Nusshold, C; Hammer, A; Kratky, D; Heinemann, A; Holzer, P; Malle, E; Sattler, W
Myeloperoxidase-derived oxidants induce blood-brain barrier dysfunction in vitro and in vivo. PLoS One. 2013; 8(5):e64034-e64034
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Walenta, E; Pessentheiner, AR; Pelzmann, HJ; Deutsch, A; Goeritzer, M; Kratky, D; Hackl, H; Oh, da Y; Prokesch, A; Bogner-Strauss, JG
α/β-hydrolase domain containing protein 15 (ABHD15)--an adipogenic protein protecting from apoptosis. PLoS One. 2013; 8(11):e79134-e79134
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Zhang, R; Yan, C; Zhou, X; Qian, B; Li, F; Sun, Y; Shi, C; Li, B; Saito, S; Horimoto, K; Zhou, H
Association of Rev-erbα in adipose tissues with Type 2 diabetes mellitus amelioration after gastric bypass surgery in Goto-Kakizaki rats. Am J Physiol Regul Integr Comp Physiol. 2013; 305(2): R134-R146.
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Bernhart, E; Damm, S; Wintersperger, A; DeVaney, T; Zimmer, A; Raynham, T; Ireson, C; Sattler, W
Protein kinase D2 regulates migration and invasion of U87MG glioblastoma cells in vitro. Exp Cell Res. 2013; 319(13):2037-2048
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Eibinger, G; Fauler, G; Bernhart, E; Frank, S; Hammer, A; Wintersperger, A; Eder, H; Heinemann, A; Mischel, PS; Malle, E; Sattler, W
On the role of 25-hydroxycholesterol synthesis by glioblastoma cell lines. Implications for chemotactic monocyte recruitment. Exp Cell Res. 2013; 319(12):1828-1838
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Huang, X; Baumann, M; Nikitina, L; Wenger, F; Surbek, D; Körner, M; Albrecht, C
RNA degradation differentially affects quantitative mRNA measurements of endogenous reference genes in human placenta. Placenta. 2013; 34(7):544-547
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Porpaczy, E; Tauber, S; Bilban, M; Kostner, G; Gruber, M; Eder, S; Heintel, D; Le, T; Fleiss, K; Skrabs, C; Shehata, M; Jager, U; Vanura, K;
Lipoprotein lipase in chronic lymphocytic leukaemia - Strong biomarker with lack of functional significance. LEUK RES. 2013; 37(6): 631-636.
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Fauland, A; Trotzmuller, M; Eberl, A; Afiuni-Zadeh, S; Kofeler, H; Guo, XH; Lankmayr, E;
An improved SPE method for fractionation and identification of phospholipids. J Sep Sci. 2013; 36(4):744-751
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Stefulj, J; Peric, M; Malnar, M; Kosicek, M; Schweinzer, C; Zivkovic, J; Scholler, M; Panzenboeck, U; Hecimovic, S
Pharmacological activation of LXRs decreases amyloid-β levels in Niemann-Pick type C model cells. Curr Pharm Biotechnol. 2013; 14(6):582-593
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Waltl-Patankar, S; Patankar, J; Fauler, G; Nusshold, C; Ullen, A; Eibinger, G; Wintersperger, A; Kratky, D; Malle, E; Sattler, W
25-Hydroxycholesterol regulates cholesterol homeostasis in the murine CATH.a neuronal cell line. Neurosci Lett. 2013; 539(4):16-21
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Radulovic, M; Knittelfelder, O; Cristobal-Sarramian, A; Kolb, D; Wolinski, H; Kohlwein, SD
The emergence of lipid droplets in yeast: current status and experimental approaches. Curr Genet. 2013; 59(4):231-242
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Stefulj, J; Panzenboeck, U; Hof, PR; Simic, G;
Pathogenesis, modulation, and therapy of Alzheimer s disease: A perspective on roles of liver-X receptors. TRANSL NEUROSCI. 2013; 4(3): 349-356.
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Suvajdzic, L; Leovac, V; Joksovic, M; Bogdanovic, G; Kojic, V; Vujic, N; Mrdja, T; Kocic, B;
Antimicrobial Activity of Copper (II) Complex with 1,2-bis [(1,3-diphenylpyrazol-4-yl)methyl] Diaminoethane. ACTA SCI VET. 2013; 41: 1123


Schaller, S; Willmann, S; Lippert, J; Schaupp, L; Pieber, TR; Schuppert, A; Eissing, T
A Generic Integrated Physiologically based Whole-body Model of the Glucose-Insulin-Glucagon Regulatory System. CPT Pharmacometrics Syst Pharmacol. 2013; 2(8):e65-e65
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2012

Kumari, M; Schoiswohl, G; Chitraju, C; Paar, M; Cornaciu, I; Rangrez, AY; Wongsiriroj, N; Nagy, HM; Ivanova, PT; Scott, SA; Knittelfelder, O; Rechberger, GN; Birner-Gruenberger, R; Eder, S; Brown, HA; Haemmerle, G; Oberer, M; Lass, A; Kershaw, EE; Zimmermann, R; Zechner, R
Adiponutrin functions as a nutritionally regulated lysophosphatidic acid acyltransferase. Cell Metab. 2012; 15(5):691-702
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Grallert, H; Dupuis, J; Bis, JC; Dehghan, A; Barbalic, M; Baumert, J; Lu, C; Smith, NL; Uitterlinden, AG; Roberts, R; Khuseyinova, N; Schnabel, RB; Rice, KM; Rivadeneira, F; Hoogeveen, RC; Fontes, JD; Meisinger, C; Keaney, JF; Lemaitre, R; Aulchenko, YS; Vasan, RS; Ellis, S; Hazen, SL; van Duijn, CM; Nelson, JJ; März, W; Schunkert, H; McPherson, RM; Stirnadel-Farrant, HA; Psaty, BM; Gieger, C; Siscovick, D; Hofman, A; Illig, T; Cushman, M; Yamamoto, JF; Rotter, JI; Larson, MG; Stewart, AF; Boerwinkle, E; Witteman, JC; Tracy, RP; Koenig, W; Benjamin, EJ; Ballantyne, CM
Eight genetic loci associated with variation in lipoprotein-associated phospholipase A2 mass and activity and coronary heart disease: meta-analysis of genome-wide association studies from five community-based studies. EUR HEART J. 2012; 33(2): 238-251.
[Fulltext][PubMed]

von Haehling, S; Schefold, JC; Jankowska, EA; Springer, J; Vazir, A; Kalra, PR; Sandek, A; Fauler, G; Stojakovic, T; Trauner, M; Ponikowski, P; Volk, HD; Doehner, W; Coats, AJ; Poole-Wilson, PA; Anker, SD
Ursodeoxycholic acid in patients with chronic heart failure: a double-blind, randomized, placebo-controlled, crossover trial. J Am Coll Cardiol. 2012; 59(6): 585-592.
[Fulltext][PubMed]

Blättermann, S; Peters, L; Ottersbach, PA; Bock, A; Konya, V; Weaver, CD; Gonzalez, A; Schröder, R; Tyagi, R; Luschnig, P; Gäb, J; Hennen, S; Ulven, T; Pardo, L; Mohr, K; Gütschow, M; Heinemann, A; Kostenis, E
A biased ligand for OXE-R uncouples Gα and Gβγ signaling within a heterotrimer. Nat Chem Biol. 2012; 8(7):631-638
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Moustafa, T; Fickert, P; Magnes, C; Guelly, C; Thueringer, A; Frank, S; Kratky, D; Sattler, W; Reicher, H; Sinner, F; Gumhold, J; Silbert, D; Fauler, G; Höfler, G; Lass, A; Zechner, R; Trauner, M
Alterations in lipid metabolism mediate inflammation, fibrosis, and proliferation in a mouse model of chronic cholestatic liver injury. Gastroenterology. 2012; 142(1):140-151
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Sedej, M; Schröder, R; Bell, K; Platzer, W; Vukoja, A; Kostenis, E; Heinemann, A; Waldhoer, M
D-type prostanoid receptor enhances the signaling of chemoattractant receptor-homologous molecule expressed on T(H)2 cells. J Allergy Clin Immunol. 2012; 129(2): 500.e1- 500.e9
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Fuchs, CD; Claudel, T; Kumari, P; Haemmerle, G; Pollheimer, MJ; Stojakovic, T; Scharnagl, H; Halilbasic, E; Gumhold, J; Silbert, D; Koefeler, H; Trauner, M
Absence of adipose triglyceride lipase protects from hepatic endoplasmic reticulum stress in mice. Hepatology. 2012; 56(1):270-280
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Quiroga, AD; Li, L; Trötzmüller, M; Nelson, R; Proctor, SD; Köfeler, H; Lehner, R
Deficiency of carboxylesterase 1/esterase-x results in obesity, hepatic steatosis, and hyperlipidemia. Hepatology. 2012; 56(6):2188-2198
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Kargl, J; Balenga, N; Parzmair, GP; Brown, AJ; Heinemann, A; Waldhoer, M
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Khan, MJ; Alam, MR; Waldeck-Weiermair, M; Karsten, F; Groschner, L; Riederer, M; Hallstroem, S; Rockenfeller, P; Konya, V; Heinemann, A; Madeo, F; Graier, WF; Malli, R
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Paar, M; Jungst, C; Steiner, NA; Magnes, C; Sinner, F; Kolb, D; Lass, A; Zimmermann, R; Zumbusch, A; Kohlwein, SD; Wolinski, H
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Leis, HJ; Donnarumma, F; Wintersteiger, R; Lazarus, R; Braml, B; Ortner, A; Windischhofer, W
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Holzer, M; Wolf, P; Curcic, S; Birner-Gruenberger, R; Weger, W; Inzinger, M; El-Gamal, D; Wadsack, C; Heinemann, A; Marsche, G
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Rengachari, S; Bezerra, GA; Riegler-Berket, L; Gruber, CC; Sturm, C; Taschler, U; Boeszoermenyi, A; Dreveny, I; Zimmermann, R; Gruber, K; Oberer, M
The structure of monoacylglycerol lipase from Bacillus sp. H257 reveals unexpected conservation of the cap architecture between bacterial and human enzymes. Biochim Biophys Acta. 2012; 1821(7):1012-1021
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Stemmer, U; Ramprecht, C; Zenzmaier, E; Stojčić, B; Rechberger, G; Kollroser, M; Hermetter, A
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Damm, M; Nusshold, C; Cantillo, D; Rechberger, GN; Gruber, K; Sattler, W; Kappe, CO
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Haybaeck, J; Stumptner, C; Thueringer, A; Kolbe, T; Magin, TM; Hesse, M; Fickert, P; Tsybrovskyy, O; Müller, H; Trauner, M; Zatloukal, K; Denk, H
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Oberbach, A; Schlichting, N; Heinrich, M; Till, H; Stolzenburg, JU; Neuhaus, J
Free fatty acid palmitate impairs the vitality and function of cultured human bladder smooth muscle cells. PLoS One. 2012; 7(7):e41026-e41026
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Philipose, S; Konya, V; Lazarevic, M; Pasterk, LM; Marsche, G; Frank, S; Peskar, BA; Heinemann, A; Schuligoi, R
Laropiprant Attenuates EP3 and TP Prostanoid Receptor-Mediated Thrombus Formation. PLoS One. 2012; 7(8):e40222-e40222
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Schröder, R; Xue, L; Konya, V; Martini, L; Kampitsch, N; Whistler, JL; Ulven, T; Heinemann, A; Pettipher, R; Kostenis, E
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Bernini, F; Costet, P; Ehrenborg, E; Fisher, R; Fielding, B; Freeman, D; Groen, A; Malle, E; Mulder, M; Niemeier, A; Hansen, AT; von Eckardstein, A
European Lipoprotein Club: Report of the 34th ELC annual conference, Tutzing, 5-8 September 2011. Atherosclerosis. 2012; 221(1):287-293
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Brkić, L; Riederer, M; Graier, WF; Malli, R; Frank, S
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Jaffer, I; Riederer, M; Shah, P; Peters, P; Quehenberger, F; Wood, A; Scharnagl, H; März, W; Kostner, KM; Kostner, GM
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Trbušić, M; Riederer, M; Vučić, M; Lovričević, I; Krušlin, B; Gauster, M; Mohrenz, S; Berghold, A; Tiran, B; Degoricija, V; Frank, S
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Leis, HJ; Windischhofer, W;
Quantitative determination of memantine in human plasma by GC using negative ion chemical ionization MS detection after derivatization with a new reagent, o-(pentafluorobenzyloxycarbonyl)-2,3,4,5-tetrafluorobenzoyl chloride. MICROCHIM ACTA. 2012; 179(3-4): 249-255.
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Leis, HJ; Windischhofer, W;
Determination of memantine in human plasma by GC using negative ion chemical ionization MS detection after derivatization with a new reagent. MICROCHIM ACTA. 2012; 178(3-4): 309-314.
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Research update for articles published in EJCI in 2010. Eur J Clin Invest. 2012; 42(11): 1149-1164.
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Birner-Gruenberger, R; Bickmeyer, I; Lange, J; Hehlert, P; Hermetter, A; Kollroser, M; Rechberger, GN; Kühnlein, RP
Functional fat body proteomics and gene targeting reveal in vivo functions of Drosophila melanogaster á-Esterase-7. Insect Biochem Mol Biol. 2012; 42(3): 220-229.
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Windischhofer, W; Huber, E; Rossmann, C; Semlitsch, M; Kitz, K; Rauh, A; Devaney, T; Leis, HJ; Malle, E
LPA-induced suppression of periostin in human osteosarcoma cells is mediated by the LPA(1)/Egr-1 axis. Biochimie. 2012; 94(9):1997-2005
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Acharya, G; Albrecht, C; Benton, SJ; Cotechini, T; Dechend, R; Dilworth, MR; Duttaroy, AK; Grotmol, T; Heazell, AE; Jansson, T; Johnstone, ED; Jones, HN; Jones, RL; Lager, S; Laine, K; Nagirnaja, L; Nystad, M; Powell, T; Redman, C; Sadovsky, Y; Sibley, C; Troisi, R; Wadsack, C; Westwood, M; Lash, GE
IFPA Meeting 2011 workshop report I: Placenta: Predicting future health; roles of lipids in the growth and development of feto-placental unit; placental nutrient sensing; placental research to solve clinical problems--a translational approach. Placenta. 2012; 33 Suppl(3):S4-S8
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Piao, G; Saito, S; Sun, Y; Liu, ZP; Wang, Y; Han, X; Wu, J; Zhou, H; Chen, L; Horimoto, K
A computational procedure for identifying master regulator candidates: a case study on diabetes progression in Goto-Kakizaki rats. BMC Syst Biol. 2012; 6 Suppl 1(5): S2-S2.
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Viertler, M; Schittmayer, M; Birner-Gruenberger, R
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Falkensammer, J; Gasteiger, S; Stojakovic, T; Stühlinger, M; Scharnagl, H; Frech, A; Fraedrich, G; Greiner, A; Huber, K
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Peterbauer-Scherb, A; Danzer, M; Gabriel, C; van Griensven, M; Redl, H; Wolbank, S
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Graulich, T; Das, SK; Krasteva, G; Ruppert, C; Wessels, L; Hoefler, G; Mühlfeld, C
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Lassance, L; Miedl, H; Konya, V; Heinemann, A; Ebner, B; Hackl, H; Desoye, G; Hiden, U
Differential response of arterial and venous endothelial cells to extracellular matrix is modulated by oxygen. Histochem Cell Biol. 2012; 137(5):641-655
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Leis, HJ; Windischhofer, W
Quantitative method for determination of amphetamine in plasma using negative ion chemical ionisation GC-MS of o-(pentafluorobenzyloxycarbonyl)-benzoyl derivatives. J Sep Sci. 2012; 35(16):2095-2100
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Leis, HJ; Windischhofer, W
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Leis, HJ; Windischhofer, W
(S)-(-)-N-(pentafluorobenzylcarbamoyl)prolyl chloride: a chiral derivatisation reagent designed for gas chromatography/negative ion chemical ionisation mass spectrometry of amino compounds. Rapid Commun Mass Spectrom. 2012; 26(6):592-598
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Stemmer, U; Dunai, ZA; Koller, D; Pürstinger, G; Zenzmaier, E; Deigner, HP; Aflaki, E; Kratky, D; Hermetter, A
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Marschall, HU; Wagner, M; Zollner, G; Fickert, P; Silbert, D; Gustafsson, U; Sahlin, S; Trauner, M
Combined rifampicin and ursodeoxycholic acid treatment does not amplify rifampicin effects on hepatic detoxification and transport systems in humans. Digestion. 2012; 86(3):244-249
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Elkin, RG; Bauer, R; Schneider, WJ
The restricted ovulator chicken strain: an oviparous vertebrate model of reproductive dysfunction caused by a gene defect affecting an oocyte-specific receptor. Anim Reprod Sci. 2012; 136(1-2):1-13
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Schicho, R; Storr, M
Topical and systemic cannabidiol improves trinitrobenzene sulfonic acid colitis in mice. Pharmacology. 2012; 89(3-4):149-155
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Cetin, I; Parisi, F; Berti, C; Mando, C; Desoye, G;
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Oberbach, A; von Bergen, M; Bluher, S; Lehmann, S; Till, H;
Combined Serum Proteomic and Metabonomic Profiling After Laparoscopic Sleeve Gastrectomy in Children and Adolescents. J Laparoendosc Adv Surg Tech A. 2012; 22(2):184-188
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Hissa, DC; Bezerra, GA; Obrist, B; Birner-Grünberger, R; Melo, VM; Gruber, K
Crystallization and preliminary X-ray diffraction of the surfactant protein Lv-ranaspumin from the frog Leptodactylus vastus. Acta Crystallogr Sect F Struct Biol Cryst Commun. 2012; 68(Pt 3):321-323
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