Peter HOLZER

Mag. rer. nat. Dr. phil.
Univ.-Prof. für Experimentelle Neurogastroenterologie

Leiter der ► Forschungseinheit für Translationale Neurogastroenterologie

Otto-Loewi-Forschungszentrum
der Medizinischen Universität Graz
Universitätsplatz 4, A-8010 Graz, Austria

Tel.: +43 (316) 385-74121
Fax: +43 (316) 385-79613
e-mail:  peter.holzer @ medunigraz.at

 

Forschungstätigkeiten Wissenschaftlicher Lebenslauf Publikationsliste
CURRICULUM VITAE / Lebenslauf

PERSONAL DATA
26.02.1951 born in Vorau, Austria

EDUCATION
1962-1970 Bischöfliches Gymnasium in Graz, Austria
1971-1976 Studies of Biology, Physiology and Biochemistry at the Faculty of Science, University of Graz, Austria
1976 M.Sc., Faculty of Science, University of Graz, Austria
1978 Ph.D. (Promotio sub auspiciis praesidentis rei publicae), Faculty of Science, University of Graz, Austria

PROFESSIONAL CAREER
1977 Assistant Professor at the Department of Experimental and Clinical Pharmacology, Faculty of Medicine, University of Graz, Austria
1980 Research Fellowship of the British Council at the ARC Institute of Animal Physiology and MRC Neurochemical Pharmacology Unit, Cambridge, United Kingdom
1985 Docent of Neuropharmacology at the Department of Experimental and Clinical Pharmacology, Faculty of Medicine, University of Graz, Austria
1989 Research Fellowship of the Max Kade Foundation at the Center for Ulcer Research and Education of the University of California at Los Angeles, United States of America
1990 Associate Professor at the Department of Experimental and Clinical Pharmacology, Faculty of Medicine, University of Graz, Austria
1993 Award of the Title of a University Professor at the Department of Experimental and Clinical Pharmacology, Faculty of Medicine, University of Graz, Austria
2000 Decline of the Chair of Pharmacology and Toxicology, Faculty of Science, University of Innsbruck, Austria
2005 Head, Research Unit of Translational Neurogastroenterology, Medical University of Graz, Austria
2008 Professor of Experimental Neurogastroenterology

ADMINISTRATIVE AND COMMITTEE SERVICES
Speaker of the Research Network "Nociception" at the Medical University of Graz
Speaker of the Research Area "Neurosciences" at the Medical University of Graz
Local Research Manager at the Department of Experimental and Clinical Pharmacology
Member of the Committee for Good Scientific Practice at the Medical University of Graz
Member of the Research Support Committee at the Medical University of Graz
Delegate of the Medical University of Graz at the Austrian Scientific Research Funds
Member of the Board of the Franz Lanyar Foundation at the Medical University of Graz
Chair of the Curricular Committee of the PhD Programme "Neuroscience"

APPOINTMENTS AND MEMBERSHIPS IN SCIENTIFIC SOCIETIES
American Gastroenterological Association (Member since 1992)
Austrian Neuroscience Association (Member since 1994, Secretary 1994-1995, Deputy Secretary 1996-1997, Vice-President 2000-2001, President 2002-2003)
Austrian Pharmacological Society (Member of the Executive Board 2007-2009, Vice-President since 2009)
Belgian Research Network on Gastrointestinal Regulatory Mechanisms (Foreign Member since 1999)
British Pharmacological Society (Member since 1982)
European DANA Alliance for the Brain (Member since 2002)
European Gastro Club (Member since 1998)
European Neuropeptide Club (Chairman 1994-1996, Deputy Chairman 1996-1998)
German Society of Experimental and Clinical Pharmacology and Toxicology (Member 1979-2002, Member of the Education Committee 1992-2002)
Initiative on Brain Research in Styria (Member of the Board 2005-2009, Treasurer since 2009)
International Association for the Study of Pain (Member since 2008)
International Neuropeptide Society (Member of the Board 1994-1996)
International Union of Pharmacology (IUPHAR), Gastrointestinal Pharmacology Section (Secretary 1994-1998, Councillor 1998-2002)

HONOURS AND AWARDS
1978 Promotio sub auspiciis praesidentis rei publicae, Faculty of Science, University of Graz
1980 Research Prize of the Hoechst Foundation, Faculty of Medicine, University of Graz
1982 Prize of the Theodor Körner Foundation for the Promotion of Science and Arts, Vienna, Austria
1982 Research Prize of the Hoechst Foundation, Faculty of Medicine, University of Graz
1984 Research Prize of the Scientific Society of Physicians in Styria, Bad Aussee, Austria
1985 Research Prize of the Hoechst Foundation, Faculty of Medicine, University of Graz
1985 Research Prize of the Kardinal Innitzer Foundation, Vienna, Austria
1988 Prize of the Theodor-Körner-Foundation for the Promotion of Science and Arts, Vienna, Austria
1988 C.A. Ewald Prize of the German Society of Gastroenterology, Heidelberg, Germany
1988 Sandoz Foundation Prize for Medicine, Vienna, Austria
1990 Carl von Rokitansky Research Prize of the Austrian Society of Pathology, Graz, Austria
1990 Research Prize of the Hoechst Foundation, Faculty of Medicine, University of Graz
1993 Award of the title of a University Professor by the Federal President of the Republic of Austria
1994 Research Prize of the Austrian Society of Rheumatology, Vienna, Austria
1997 Josef Krainer Prize for Experimental and Clinical Pharmacology, Graz, Austria
2001 Research Prize of the Province of Styria, Graz, Austria
2001 Societas Physiologorum Polonorum Medal, Polish Physiological Society and Jagiellonian University Cracow, Poland
2002 Honorary Member of the Società di Medicina e Scienze Naturali di Parma, Italy
2003 Miklós Jancsó Prize, University of Szeged, Hungary
2003 Medal of Pioneers, Polish Physiological Society and Jagiellonian University Cracow, Poland
2003 Highly Cited Author in Pharmacology, ISIHighlyCited.com
2006 Award of the Great Decoration for Service to the Republic of Austria (Großes Ehrenzeichen für Verdienste um die Republik österreich)
2006 Masters Award for Basic Science in Digestive Sciences, American Gastroenterological Association
2010 Member of the Faculty of 1000 (Gastroenterology and Hepatology)

COAUTHOR OF PRIZES AWARDED TO SCIENTIFIC COLLABORATORS
1984 Research Prize of the Hoechst Foundation, Faculty of Medicine, University of Graz
1987 Research Prize of the Hoechst Foundation, Faculty of Medicine, University of Graz
1989 F. Wewalka Memorial Prize of the Austrian Society of Gastroenterology
1989 Research Prize of the Hoechst Foundation, Faculty of Medicine, University of Graz
1997 Research Prize of the Hoechst Foundation, Faculty of Medicine, University of Graz
1999 Research Prize of the Hoechst Foundation, Faculty of Medicine, University of Graz
1999 Basler Pize for Scientific Research by Students of the Medical Faculty of the University of Graz
2000 Research Prize of the Aventis Foundation, Faculty of Medicine, University of Graz
2001 Research Prize of Bank Austria for Students at the University of Graz
2001 Research Prize of the Aventis Foundation, Faculty of Medicine, University of Graz
2003 Research Prize of the Aventis Foundation, Faculty of Medicine, University of Graz
2004 Research Prize of the Austrian Pain Society
2006 Awards of the Research Prizes 2005 of INGE St. (Initiative on Brain Research in Styria, Initiative Gehirnforschung Steiermark)
2008 Research Prize of the Austrian Pain Society

RESEARCH FUNDING AND GRANTS
1982-1985 "Functions of gastrointestinal peptidergic neurons" (Principal Investigator; FWF Austrian Science Funds)
1985-1988 "Physiology and pathophysiology of substance P-containing neurons in the gastrointestinal tract" (Principal Investigator; Austrian Research Foundation)
1987 "Peptidergic nature of noncholinergic nonadrenergic transmission in the gut" (Co-Investigator; European Science Foundation)
1988 "Do capsaicin-sensitive afferent neurones protect the gastric mucosa against damage by stimulation of gastric bicarbonate secretion?" (Principal Investigator; Franz Lanyar Foundation)
1988-1989 "Role of capsaicin-sensitive afferent neurones in the pathogenesis of gastric mucosal damage: a novel endogenous mechanism of gastric mucosal protection" (Principal Investigator; Max Kade Foundation)
1990-1993 "Physiology and pathophysiology of peptidergic neurons in the control of gastric mucosal blood flow and protection and in the control of gastrointestinal motor activity" (Principal Investigator; FWF Austrian Science Funds)
1992-1993 "Neural control of gastrointestinal circulation" (Principal Investigator; Austrian National Bank)
1993-1996 "Vascular regulation by peptidergic neurons" (Principal Investigator; FWF Austrian Science Funds)
1993-1996 "Inflammatory mediators and functional plasticity of afferent neurons" (Principal Investigator; FWF Austrian Science Funds)
1994-1995 "Role of neuropeptides in irritative disturbances of intestinal motility" (Principal Investigator; Austrian-Hungarian Foundation)
1994-1995 "Inflammation and neuropeptide expression in nociceptive afferent neurons" (Principal Investigator; Austrian National Bank)
1995-1996 "Site of action of the signal for gastric blood flow regulation in physiological and pathological conditions" (Co-Investigator; Acciones Integradas Hispano-Austriacas)
1997-1998 "Molecular biology of visceral nociception" (Principal Investigator; Austrian National Bank)
1997-2001 "Functional and phenotypic plasticity of sensory neuropeptide systems in visceral injury and inflammation" (Principal Investigator; FWF Austrian Science Funds)
2000-2002 "Neuroimmunology of gastric mucosal disease: immune system - sensory neuron interaction as a clue for dyspepsia?" (Principal Investigator; Federal Ministry of Education, Science and Culture of the Republic of Austria)
2000-2002 "Development and validation of a method for studying peristalsis on multiple segments of the guinea-pig isolated small intestine: replacement of animal experiments and saving of animal lives through refined in vitro methodology" (Principal Investigator; Federal Ministry of Education, Science and Culture of the Republic of Austria)
2000-2004 "Neuropharmacology of dyspepsia" (Principal Investigator; FWF Austrian Science Funds)
2001-2002 "Mechanisms of perception during jejunal capsaicin perfusion" (Co-Investigator; FWF Austrian Science Funds)
2001-2004 "Effect of tegaserod on colonic circulation" (Principal Investigator; Novartis, Switzerland)
2003-2005 "Gene knockout approach to the neuropharmacology of dyspepsia" (Principal Investigator; Austrian National Bank)
2003-2009 "The gastrointestinal nervous system as novel therapeutic target in functional bowel disorders" (Principal Investigator; Zukunftsfonds Steiermark)
2005-2006 "Links between visceral dysfunction and affective disorders" (Principal Investigator; European Science Foundation)
2005-2008 "Translational neurogastroenterology" (Principal Investigator; FWF Austrian Science Funds)
2006-2007 "Receptor-mediated gastric mucosal protection: new approach to stimulation of gastric mucosal defence" (Co-Investigator; Hungarian-Austrian Intergovernmental S&T Cooperation Programme)
2007 "Effect of lafutidine on gastric acid-evoked c-Fos expression in the rat brainstem" (Taiho Pharmaceutical Co. Ltd., Tokyo, Japan)
2008 "Effect of YKP10811 on nerve-muscle preparations of the guinea-pig small intestine" (SK Life Science, Fair Lawn, New Jersey, USA)
2008-2009 "Investigation of the effect of lafutidine to facilitate acid elimination in the normal and inflamed rat stomach (Taiho Pharmaceutical Co. Ltd., Tokyo, Japan)
2008-2011 "Effect of environmental enrichment on emotional behaviour and the gut-brain axis in mice" (Principle Investigator, Federal Ministry of Science and Research of the Republic of Austria)
2010-2011 "TRPA1 as biomarker of multiple chemical sensitivity"(Principal Investigator; Land Steiermark)
2011-2014 "Psychopharmacological modelling of ongoing visceral pain" (Principal Investigator; FWF Austrian Science Funds)
2011-2014 "Analysis of the genetic basis of multiple chemical sensitivity by exome sequencing" (Principal Investigator; Federal Ministry of Life of the Republic of Austria)

INDUSTRIAL COOPERATIONS
Allergosan (Austria)
Altana Pharma (Germany)
AstraZeneca (Sweden)
Boehringer-Ingelheim (Germany)
Heel (Germany)
ISO Health Care Group (United States of America)
Lannacher (Austria)
McKinsey (United States of America)
Medosan & Sigma-Tau (Italy)
Menarini Research and Development (Italy)
Menarini Group (Spain)
Merck, Sharp & Dohme (United Kingdom)
Mundipharma (Germany)
Novartis (Switzerland)
Perstorp (Sweden)
SK Life Science (USA)
Solvay (Germany)
Strategic Consultants (United Kingdom)
Taiho Pharmaceuticals (Japan)
TAP Pharmaceuticals (United States of America)
Wyeth (Austria)
Xenova Limited (United Kingdom)

ADVISORY SERVICES
Federal Ministry of Education, Science and Culture of the Republic of Austria (Austria)
Federal Ministry of Interior of the Republic of Austria (Austria)
Federal Ministry of Law of the Republic of Austria (Austria)

EDITORIAL BOARD MEMBERSHIPS
BMC Gastroenterology (Member of the Editorial Board since 2005)
British Journal of Pharmacology (Editor 1996-1999, 2006-2010)
Current Neuropharmacology (Member of the Editorial Board 2002-2003)
Digestion (Member of the Editorial Board 2000-2003)
European Journal of Pharmacology (Consultant of the Editor 1991-2008)
Faculty of 1000, Gastroenterology and Hepatology (Member since 2010)
Frontiers in Enteric Neuroscience (Reviewing Editorial Board Member since 2009)
Frontiers in Gastrointestinal Sciences (Reviewing Editorial Board Member since 2010)
Fundamental and Clinical Pharmacology (Field Editor 2001-2006)
ISRN Gastroenterology (Member of the Editorial Board since 2009)
Journal of Physiology and Pharmacology (Member of the Editorial Board since 2003)
Life Sciences (Editor 2007-2011)
Naunyn-Schmiedeberg's Archives of Pharmacology (Advisory Editor 1986-2003)
Neurogastroenterology and Motility (Member of the Editorial Board 2001-2008)
Neuroscience (Editor 1988-2002)
Pharmacology and Therapeutics (Associate Editor since 2008)
Regulatory Peptides (Editor 1995-2002)

SERVICE AS REVIEWER FOR SCIENTIFIC JOURNALS
Acta Physiologica -- Agents and Actions -- Alimentary Pharmacology & Therapeutics - American Journal of Gastroenterology -- American Journal of Physiology -- Anatomical Record -- Anesthesiology -- Archives Internationales de Pharmacodynamie et de Therapie -- Arthritis & Rheumatism -- Autonomic Neuroscience: Basic and Clinical -- Basic & Clinical Pharmacology & Toxicology -- Behavioral and Neural Biology -- BMC Clinical Pharmacology -- Brain Research -- Brain Research Bulletin -- British Journal of Pharmacology -- Canadian Journal of Physiology and Pharmacology -- Cell and Tissue Research -- Clinical Autonomic Research -- Clinical Science -- Comparative Biochemistry and Physiology -- Comptes Rendus de L'Academie des Sciences Paris -- Critical Reviews in Food Science and Nutrition -- Current Opinion on Investigational Drugs -- Current Pharmaceutical Biotechnology -- Current Topics in Medicinal Chemistry -- Digestion -- Digestive Diseases and Sciences -- Drug Discovery Today -- Drugs and Aging -- European Journal of Gastroenterology and Hepatology -- European Journal of Pain -- European Journal of Pharmacology -- European Journal of Physiology -- Experimental Brain Research -- Experimental Physiology -- Expert Opinion on Investigational Drugs -- Expert Opinion on Pharmacotherapy -- Expert Opinion on Therapeutic Targets -- FASEB Journal -- Fundamental & Clinical Pharmacology -- Gastroenterology -- General Pharmacology -- Gut -- Inflammation Research -- International Journal of Hyperthermia -- International Journal of Nutrition and Metabolism -- Journal of Applied Physiology -- Journal of Autonomic Pharmacology -- Journal of Clinical Investigation -- Journal of Comparative Neurology -- Journal of Comparative Physiology A -- Journal of Gastroenterology and Hepatology -- Journal of Gastrointestinal Motility -- Journal of Molecular Medicine -- Journal of Neural Transmission -- Journal of Neurochemistry -- Journal of Neurophysiology -- Journal of Neuroscience -- Journal of Pain -- Journal of Pain and Symptom Management -- Journal of Pharmacology and Experimental Therapeutics -- Journal of Pharmacy and Pharmacology -- Journal of Physiology (London) -- Journal of Physiology and Pharmacology -- Journal of Psychopharmacology -- Journal of Rheumatology -- Journal of Urology -- Life Sciences -- Molecular Pain -- Nature Medicine -- Naunyn-Schmiedeberg's Archives of Pharmacology -- Neurogastroenterology and Motility -- Neuropharmacology -- Neuroscience -- Neuroscience Biobehavioral Reviews -- Neuroscience Letters -- Neurotoxicology and Teratology -- New England Journal of Medicine -- Pain -- Peptides -- Pharmacological Reviews -- Pharmacology -- Pharmacology Biochemistry and Behavior -- Pharmacology & Therapeutics -- Pharmacology & Toxicology -- Physiology & Behavior -- Planta Medica -- PloS ONE -- Proceedings of the National Academy of Sciences, U.S.A. -- Proceedings of the Society for Experimental Biology and Medicine -- Psychological Medicine -- Psychoneuroendocrinology -- Regulatory Peptides -- Scandinavian Journal of Gastroenterology -- Trends in Pharmacological Sciences

SERVICE AS REVIEWER FOR GRANT AGENCIES AND SCIENCE FOUNDATIONS
Agence d'Evaluation de la Recherche et de l'Enseignement Supérieur (AERES, France) -- Agence Nationale de la Recherche (ANR, France) -- Alberta Heritage Foundation for Medical Research (Canada) -- Alexander von Humboldt-Stiftung (Germany) -- Arthritis Research Campaign (United Kingdom) -- Austrian National Bank, Jubilee Foundation (Austria) -- Austrian Science Funds (FWF, Austria) -- Basic Research Foundation of the Israel Academy of Sciences and Humanities (Israel) -- Belgian Science Foundation (Belgium) -- Biotechnology and Biological Sciences Research Council (UK) -- Broad Foundation Medical Research Program (United States of America) -- Catalan Agency for Health Technology Assessment and Research (Spain) -- Comitato di Indirizzo per la Valutazione della Ricerca (CIVR, Italy) -- Continuous Medical Education Programme in Gastroenterology and Hepatology (Spain) -- Crohn's and Colitis Foundation of Canada (Canada) -- Dr. Hadwen Trust for Humane Research (UK) -- European Commission, Fourth Frame Programme, BIOMED 2 (Belgium) -- European Commission, Life Sciences Panel: Marie Curie Fellowships (Belgium) -- European Research Council (Belgium) -- European Science Foundation (France) -- Federal Ministry of Science and Research of the Republic of Austria: Agency for Academic Cooperation and Motility (Austria) -- Federal Ministry of Science and Research of the Republic of Austria: Hungarian-Austrian Intergovernmental S&T Cooperation Programme (Austria) -- Federal Ministry of Science and Research of the Republic of Austria: National Neuroscience Programme (Austria) -- Flanders Funds for Scientific Research (Belgium) -- Fondation pour la Recherche Médicale - Equipes (FRM, France) -- Franz Lanyar Foundation (Austria) -- Hong Kong University Grants Committee (Hong Kong) -- Institut national de la santé et de la recherché médicale (INSERM, France) -- International Human Frontier Science Program (France) -- International Science Foundation (United States of America) -- Interuniversity Attraction Poles Funding Programme (Belgium) -- Israel Science Foundation (Israel) -- Italian National Research Council (Italy) -- Medical Research Council (UK) -- Medical-Scientific Funds of the Mayor of Vienna (Austria) -- National Health and Medical Research Council (Australia) -- National Office for Research and Technology (NKTH, Hungary) -- NATO Collaborative Research Grants (Belgium) -- Swiss National Research Funds (Switzerland) -- Tyrolean Research Funds (Austria) -- Uffizio Valorizzazione Ricerca Biomedica e Farmaceutica Regione Toscana (Italy) -- University of Antwerp Joint Research Council (Belgium) -- Wellcome Trust (UK) -- Wilhelm-Sander-Stiftung (Germany)

SERVICE AS REVIEWER FOR UNIVERSITIES
Bernstein Center for Computational Neuroscience, University of Freiburg (Germany) -- Charité Universitätsmedizin Berlin (Germany) -- Chinese University of Hong Kong (China) -- Comenius University Bratislava (Slovakia) -- King Saud University (Saudia Arabia) -- Louisiana State University (United States of America) -- Medical University of Innsbruck (Austria) -- New York Academy of Sciences (United States of America) -- Paracelsus Medical University Research Fund (Austria) -- Queen's University of Belfast (UK) -- Southern Illinois University (United States of America) -- University College Cork (Ireland) -- University of Antwerp (Belgium) -- University of Auckland (New Zealand) -- University of Barcelona (Spain) -- University of California at San Diego (United States of America) -- University of California at Los Angeles (United States of America) -- University of Erlangen-Nürnberg (Germany) -- University of Graz (Austria) -- University of Innsbruck (Austria) -- University of Marburg (Germany) -- University of Melbourne (Australia) -- University of Michigan at Ann Arbor (United States of America) -- University of Newcastle (Australia) -- University of New South Wales in Sydney (Australia) -- University of Pittsburgh (United States of America) -- University of Tasmania (Australia) -- University of Toronto (Canada) -- University of Virginia (United States of America) -- University of Würzburg (Germany) -- Veterinary University of Hannover (Germany) -- Washington University at St. Louis (United States of America)

ORGANIZATION OF SCIENTIFIC CONFERENCES
1985 Symposium "Neuroscience in Austria 1985", Vienna, Austria, November 1985
1988 International Symposium on Tachykinins, Graz, Austria, July 1988
1991 International Symposium on Calcitonin Gene-Related Peptide under the auspices of the New York Academy of Sciences, Graz, Austria, July 1991
1992 Fall Meeting of the German Society of Pharmacology and Toxicology, Graz, Austria, September 1992
1993 Basic Neuroscience and Neurochemistry, Austrian-Hungarian Joint Meeting, Sopron, Hungary, September 1993
1995 Annual Meeting of the Austrian Neuroscience Association, Graz, Austria, September 1995
1998 Seventh Scientific Meeting of the Austrian Pain Society, Graz, April 1998
1998 International Symposium on Problems of the Gastrointestinal Tract in Anaesthesia, the Perioperative Period, and Intensive Care, Würzburg, Germany, October 1998
2001 Symposium on Neurogastroenterology as an Emerging Field for Gastrointestinal Pharmacotherapy at the Third Meeting of the Federation of the European Pharmacological Societies (EPHAR), Lyon, France, July 2001
2001 Annual Meeting of the Austrian Neuroscience Association, Seggauberg, Austria, September 2001
2006 Exploratory Workshop of the European Science Foundation on "Links between Visceral Dysfunction and Affective Disorders", Graz, Austria, September 2006
2007 International Symposium on "Gastrointestinal Motility: from Physiology to Therapy", Rome, Italy, September 2007
2009 2009 Falk Symposium 170 on "IBD and IBS: Novel Mechanisms and Future Practice", Glasgow, UK, September 2009
2009 15th Scientific Symposium of the Austrian Pharmacological Society (APHAR), Graz, Austria, November 2009


30.08.2011