Seminare Seminars ]


Invitation to a Research Seminar:
"Intravital Microscopy: Disturbance of the Microcirculation During Sepsis"
(Priv.-Doz. Ass.-Prof. Dr. Georg SINGER, Department of Pediatric Surgery, Medical Universit of Graz)
Date: Monday, 21 November 2011
Time: 15:00 hrs
Location Social Room of the Institute of Experimental and Clinical Pharmacology, Universitätsplatz 4 / 3rd floor (Room 022)
Invitation to a Research Seminar:
Animal Models of Mood Disorders: From Mice to Men?
Dr. Daniela POLLAK (Department of Physiology, Medical University of Vienna; former PostDoc with Nobel Prize Winner Eric Kandel)
Friday, 19 March 2010
HS 04.01 (Universitätsplatz 4, EG)

"Although depression – among other mood disorders – represents one of the most common health problems world-wide, it is currently diagnosed solely on clinical grounds, since knowledge about the underlying patho-physiological principles is still very scanty. The implementation of proper animal models is a prerequisite for increasing the understanding of the neurobiological basis of mood disorders and for the development of alternative therapeutic interventions. ..." (more)

Einladung zu einem Forschungsseminar:
The dopamine transporter: molecular structure and cellular regulation
Univ.-Prof. Dr. Ulrik GETHER (Department of Pharmacology, The Panum Institute, University of Copenhagen)
Donnerstag, 26.11.2009, 17:00h
Hörsaal 04.11, Universitätsplatz 4/I. Stock

"The dopamine transporter (DAT) belongs to the SLC6 (solute carrier 6) gene family of Na+/Cl-dependent transporters and mediates rapid reuptake of dopamine from the synaptic cleft. Moreover, DAT is the principle target for widely abused psychostimulants, such as cocaine and amphetamines. ..." more

Antitumoral effects of cannabinoids: From bench to bedside
(Prof. Cristina SÁNCHEZ, Complutense University, Madrid)

"It has recently been discovered that cannabinoids - the active components of marijuana and their derivatives - possess antitumoral properties. A wide variety of cannabinoid compounds inhibit the survival of various tumor cells in culture and, more importantly, curb the growth of different models of tumor xenografts in rats and mice. ..." more

Using intra-molecular FRET to study receptor confirmations in living cells
(Prof. Robert TAMPÉ, Institut für Biochemie, Universität Frankfurt)

"A challenging task for the adaptive immune system of vertebrates is to identify and eliminate intracellular antigens. Taking advantage of the constant turnover of proteins, a highly specialized antigen presentation machinery has evolved that displays degradation products to effectorcells of the immune system at the cell surface. ..." more

Using intra-molecular FRET to study receptor confirmations in living cells
(Dr. Carsten HOFFMANN, Institut für Pharmakologie, Universität Würzburg)

"Using our recently developed fluor-escenceresonance energy approach (FRET) we are able to detect agonist induced conformational changes of GPCRsin living cells. We have developed a method to replace the typically large fluorescent proteins by a small soluble fluorescent dye, called FlAsH. ..." more

Tumor surveillance in leukemia – NK cells entre the stage!
(Univ.-Prof. Dr. Veronika SEXL, Institut für Pharmakologie, Medizinische Universität Wien)

"In mice and men it has been shown that NK cells efficiently recognize and eliminate leukemic cells. This talk will introduce you to the basics of NK cellbiology and the secrets of how to turn a sleeping beauty into a sophisticated killer. ..." more

ER export of membrane proteins: quaint cell biology or a treasure-trove for pharmacology?
(Univ.-Prof. Michael FREISSMUTH, Institut für Pharmakologie, Medizinische Universität Wien)

"Prof. Michael Freissmuth will share his lab's latest data about how membrane proteins (e.g. GPCRs and transporters) are subjectto stringent quality control while they are folded in the endoplasmic reticulum (ER). ..." more

The mechanism of pharmacochaperoning exemplyfied on the A1 adenosine receptor
(Dr. Christian NANOFF, Pharmakologisches Institut, Medizinische Universität Wien)

"Export of membrane proteins from the site of biosynthesis, i.e. the endoplasmic reticulum, to the plasma membrane depends on proper folding of the polypeptide. A misfoldedprotein is retained until the defect has been corrected or the protein becomes degraded. ..." more

Mrs2 forms a high conductance Mg2+-permeable channel in mitochondria
(Dr. Rainer SCHINDL, Institut für Biophysik, Universität Linz)
Novel functions for orphan GPCRs – insights from heterodimers
(Prof. Dr. Ralf JOCKERS, Institut Cochin, INSERM, Université Paris)
Cyclooxygenase-1 derived prostaglandins are essential for intestinal integrity - just a myth?
(Dr. Christoph HOTZ-BEHOFSITS, King's College London)
The Recent History and Future of Platelets in Thrombosis and Other Disorders
(Prof. Gustav V.R. BORN, William Harvey Research Institute and Emeritus Professor of Pharmacology in the University of London)
Tailor-made immune responses with naked DNA vaccines
(Prof. Josef THALHAMER, Department of Molecular Biology, University of Salzburg)
Synaptic Amplifier of Inflammatory Pain in the Spinal Dorsal Horn
(Dr. Johanna STARK, Department of Neurophysiology, Center for Brain Research, Medical University of Vienna)
Pharmacological Analysis of the Effect of α2 Adrenoceptors on Gastric Motor Activity
(Dr. Zoltán ZÁDORI, Dept. of Pharmacology and Pharmacotherapy, Semmelweis University, Budapest)
Involvement of Different α2 Adrenoceptor Subtypes in Different GI Functions
(Prof. Klára GYIRES, Head, Dept. of Pharmacology and Pharmacotherapy, Semmelweis University, Budapest)
Jaks and STATs – for the Better or Worse in Leukemia Development
(Univ.-Prof. Dr. Veronika SEXL, Zentrum für Biomolekulare Medizin und Pharmakologie, Wien)
Inflammatory Stress as a Susceptibility Factor in Hepatotoxicity: Is There a Connection to Idiosyncratic Drug Reactions?
(Prof. Robert A. ROTH, National Food Safety and Toxicology Center, Michigan State University)
Raging to Social: G-protein Determinants of Addiction
(M. Scott BOWERS, Ph.D., Ernest Gallo Clinic and Research Center, University of California, San Francisco)
Cannabinoid receptor dynamics
(Prof. Andrew IRVING, Neurosciences Institute, Department of Pathology and Neuroscience University of Dundee, Ninewells Hospital & Medical School, Scotland)
Examination of receptor and transporter mobility in living cells by fluorescence microscopy
(Univ.-Prof. Dr. Harald SITTE, Zentrum für Biomolekulare Medizin und Pharmakologie, Medizinische Universität Wien)
A novel immuno-modulator of dendritic cells inhibits allergic lung inflammation
(Dr. Maximilian WOISETSCHLÄGER, Novartis Forschungsinstitut Wien)
From viruses to opioids – Trafficking, signaling and drug targeting of G protein-coupled receptors (GPCRs) involved in virus assembly and addiction
(Dr. Maria WALDHOER, Ernest Gallo Clinic & Research Center, UCSF)
Neuropeptide Y: from molecule to function in intestinal targets including enteric neurons
(Prof. Helen COX, Centre for Neuroscience Research, King's College London, GKT School of Biomedical Sciences)
Funktionelle und psychopharmakologische Evaluierung eines Tiermodells affektiver Erkrankungen
(Christoph THÖRINGER, Max-Planck-Institut für Psychiatrie, München)
Scorpion sting - a pain in the pancreas
(Prof. Gino SACCONE, Pancreatobiliary Research Group, Department of Surgery, Flinders University, Flinders Medical Centre, Bedford Park, SA, Australia)
Stress sensitisation: a tale of brain and body
(Prof. Dr. Rianne STAM, Rudolf Magnus Institute of Neuroscience, University Medical Centre Utrecht, The Netherlands)
Die Rolle lysosomaler Cysteinproteinasen in der Initialphase der akuten Pankreatitis
(Prof. Walter Halangk, Experimentelle Operative Medizin, Zentrum für Chirurgie der Otto-von-Guericke-Universität Magdeburg)
PBL (Problem-Based Learning) for the Few and the Many
(Prof. P.K. RANGACHARI, Professor of Pharmacology and Therapeutics, Director of Inquiry, O'Brien Centre for the B.HSc. Programme, Faculty of Medicine, University of Calgary, Calgary, Alberta, Canada)
Involvement of Protein Kinase C in beta-Adrenergic Responses in Guinea-Pig Cardiomyocytes
(Dr. Ivo JURÁNEK, Institute of Experimental Pharmacology, Slovak Academy of Sciences, Bratislava)
Regulation of Ghrelin by Nutrients in the Gut
(Dr. Joost OVERDUIN, Dept. of Medicine, Univ. of Washington Med. School, Seattle, WA, U.S.A.)
Integration of short and long-term signals in the neural control of food intake
(Prof. Dr. Hans-Rudolf BERTHOUD, Lab. of Neurobiology of Nutrition, Pennington Biomed. Res. Ctr., Louisiana State University, Baton Rouge, LA, U.S.A.)
Eosinophils in the asthmatic lung: what's the attraction?
(Prof. Timothy J. WILLIAMS, Imperial College Faculty of Medicine, London, U.K.)
Human models of visceral hypersensitivity
(Dr. Anthony R. HOBSON, GI Sciences, Hope Hospital, Salford, U.K.)
Die komplexe Innervation des Oesophagus
(Prof. Winfried L. NEUHUBER, Erlangen)
The Molecular Biology of Chemokine Receptors
(Dr. James PEASE, Imperial College, London)
Wirkung von Nichtopioid-Analgetika auf die Dünndarmperistaltik
(Prof. Michael K. HERBERT und Rebecca WEIS, Würzburg)
Zytokine und Nociception
(Prof. Michaela KRESS, Erlangen)
Der Capsaicinrezeptor: Drehscheibe pro- und antinozizeptiver Einflüsse
(Prof. Peter REEH, Erlangen)