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Publications

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2016

Drosatos K, Pollak NM, Pol CJ, Ntziachristos P, Willecke F, Valenti MC, Trent CM, Hu Y, Guo S, Aifantis I, Goldberg IJ. Circ Res. 2016; 118(2):241-53. doi: 10.1161/CIRCRESAHA.115.306383

Chauvet S, Jarvis L, Chevallet M, Shrestha N, Groschner K, Bouron A. Pharmacological Characterization of the Native Store-Operated Calcium Channels of Cortical Neurons from Embryonic Mouse Brain. Front Pharmacol. 2016; 7:486 doi: 10.3389/fphar.2016.00486
Corrigendum in Front Pharmacol. 2017; 8:152 doi: 10.3389/fphar.2017.00152

Carmona-Gutierrez D, Kainz K, Madeo F. Sexually transmitted infections: old foes on the rise. Microb Cell. 2016; 3(9):361-2 doi: 10.15698/mic2016.09.522

Zimmermann A, Kainz K, Andryushkova A, Hofer S, Madeo F, Carmona-Gutierrez D. Autophagy: one more Nobel Prize for yeast. Microb Cell. 2016; 3(12):579-81 doi: 10.15698/mic2016.12.544

Bettermann K*, Mehta AK*, Hofer EM, Wohlrab C, Golob-Schwarzl N, Svendova V, Schimek MG, Stumptner C, Thüringer A, Speicher MR, Lackner C, Zatloukal K, Denk H, Haybaeck J. Keratin 18-deficiency results in steatohepatitis and liver tumors in old mice: A model of steatohepatitis-associated liver carcinogenesis. Oncotarget. 2016; 7(45): 73309-22 doi: 10.18632/oncotarget.12325 (*equal contribution)

Madreiter-Sokolowski CT, Klec C, Parichatikanond W, Stryeck S, Gottschalk B, Pulido S, Rost R, Eroglu E, Hofmann NA, Bondarenko AI, Madl T, Waldeck-Weiermair M, Malli R, Graier WF. PRMT1-mediated methylation of MICU1 determines the UCP2/3 dependency of mitochondrial Ca2+ uptake in immortalized cells. Nat Commun. 2016; 7:12897 doi: 10.1038/ncomms12897

Madreiter-Sokolowski CT, Gottschalk B, Parichatikanond W, Eroglu E, Klec C, Waldeck-Weiermair M, Malli R, Graier WF. Resveratrol specifically kills cancer cells by a devastating increase in the Ca2+ coupling between the greatly tethered endoplasmic reticulum and mitochondria. Cell Physiol Biochem. 2016;39(4):1404-20 doi: 10.1159/000447844

Lahiri P, Schmidt V, Smole C, Kufferath I, Denk H, Strnad P, Rülicke T, Fröhlich LF, Zatloukal K. p62/Sequestosome-1 Is Indispensable for Maturation and Stabilization of Mallory-Denk Bodies. PLoS One. 2016; 11(8):e0161083 doi: 10.1371/journal.pone.0161083

Yang H, Ni HM, Guo F, Ding Y, Shi YH, Lahiri P, Fröhlich LF, Rülicke T, Smole C, Schmidt VC, Zatloukal K, Cui Y, Komatsu M, Fan J, Ding WX. Sequestosome-1/p62 is Associated with Autophagic Removal of Excess Hepatic Endoplasmic Reticulum in Mice. J Biol Chem. 2016; 291(36):18663-74 doi: 10.1074/jbc.M116.739821

Plastira I, Bernhart E, Goeritzer M, Reicher H, Kumble VB, Kogelnik N, Wintersperger A, Hammer A, Schlager S, Jandl K, Heinemann A, Kratky D, Malle E, Sattler W. 1-Oleyl-lysophosphatidic acid (LPA) promotes polarization of BV-2 and primary murine microglia towards an M1-like phenotype. J Neuroinflammation. 2016; 13(1):205 doi: 10.1186/s12974-016-0701-9

Svobodova B, Groschner K. Reprint of "Mechanisms of lipid regulation and lipid gating in TRPC channels". Cell Calcium. 2016; 60(2):133-41 doi: 10.1016/j.ceca.2016.06.010

Sturmberger L, Wallace PW, Glieder A, Birner-Gruenberger R. Synergism of proteomics and mRNA sequencing for enzyme discovery. J Biotechnol. 2016; 235:132-8 doi: 10.1016/j.jbiotec.2015.12.015

Tiapko O, Bacsa B, de la Cruz GG, Glasnov T, Groschner K. Optopharmacological control of TRPC channels by coumarin-caged lipids is associated with a phototoxic membrane effect. Sci China Life Sci. 2016; 59(8):802-10 doi: 10.1007/s11427-016-5095-5

Grumet L, Eichmann TO, Taschler U, Zierler KA, Leopold C, Moustafa T, Radovic B, Romauch M, Yan C, Du H, Haemmerle G, Zechner R, Fickert P, Kratky D, Zimmermann R, Lass A. Lysosomal acid lipase hydrolyzes retinyl ester and affects retinoid turnover. J Biol Chem. 2016; 291(34):17977-87 doi: 10.1074/jbc.M116.724054

Ulz P, Belic J, Graf R, Auer M, Lafer I, Fischereder K, Webersinke G, Pummer K, Augustin H, Pichler M, Hoefler G, Bauernhofer T, Geigl JB, Heitzer E, Speicher MR. Whole-genome plasma sequencing reveals focal amplifications as a driving force in metastatic prostate cancer. Nat Commun. 2016; 7:12008 doi: 10.1038/ncomms12008

Al-Zoughbi W, Pichler M, Gorkiewicz G, Guertl-Lackner B, Haybaeck J, Jahn SW, Lackner C, Liegl-Atzwanger B, Popper H, Schauer S, Nusshold E, Kindt ASD, Trajanoski Z, Speicher MR, Haemmerle G, Zimmermann R, Zechner R, Vesely PW, Hoefler G. Loss of Adipose Triglyceride Lipase is associated with human cancer and induces mouse pulmonary neoplasia. Oncotarget. 2016; 7(23):33832-40 doi: 10.18632/oncotarget.9418

Vinod M, Patankar JV, Sachdev V, Frank S, Graier WF, Kratky D, Kostner GM. MiR-206 is expressed in pancreatic islets and regulates glucokinase activity. Am J Physiol Endocrinol Metab. 2016; 311(1):E175-85 doi: 10.1152/ajpendo.00510.2015

Sachdev V, Leopold C, Bauer R, Patankar JV, Iqbal J, Obrowsky S, Boverhof R, Doktorova M, Scheicher B, Goeritzer M, Kolb D, Turnbull AV, Zimmer A, Hoefler G, Hussain MM, Groen AK, Kratky D. Novel role of a triglyceride-synthesizing enzyme: DGAT1 at the crossroad between triglyceride and cholesterol metabolism. Biochim Biophys Acta. 2016; 1861(9 Pt A):1132-41 doi: 10.1016/j.bbalip.2016.06.014

Radovic B, Vujic N, Leopold C, Schlager S, Goeritzer M, Patankar JV, Korbelius M, Kolb D, Reindl J, Wegscheider M, Tomin T, Birner-Gruenberger R, Schittmayer M, Groschner L, Magnes C, Diwoky C, Frank S, Steyrer E, Du H, Graier WF, Madl T, Kratky D. Lysosomal acid lipase regulates VLDL synthesis and insulin sensitivity in mice. Diabetologia. 2016; 59(8):1743-52 doi: 10.1007/s00125-016-3968-6

Vujic N, Porter Abate J, Schlager S, David T, Kratky D, Koliwad SK. Acyl-CoA:diacylglycerol acyltransferase 1 expression level in the hematopoietic compartment impacts inflammation in the vascular plaques of atherosclerotic mice. PLoS One. 2016; 11(5):e0156364 doi: 10.1371/journal.pone.0156364

Svobodova B, Groschner K. Mechanisms of lipid regulation and lipid gating in TRPC channels. Cell Calcium. 2016; 59(6):271-9 doi: 10.1016/j.ceca.2016.03.012

Carmona-Gutierrez D, Kainz K, Madeo F. Sexually transmitted infections: old foes on the rise. Microb Cell. 2016; 3(9):361-2. doi: 10.15698/mic2016.09.522

Prokesch A*, Pelzmann HJ*, Pessentheiner AR, Huber K, Madreiter-Sokolowski CT, Drougard A, Schittmayer M, Kolb D, Magnes C, Trausinger G, Graier WF, Birner-Gruenberger R, Pospisilik JA, Bogner-Strauss JG. N-acetylaspartate catabolism determines cytosolic acetyl-CoA levels and histone acetylation in brown adipocytes. Sci Rep. 2016; 6:23723 doi: 10.1038/srep23723 (*equal contribution)

Huang J, Li L, Lian J, Schauer S, Vesely PW, Kratky D, Hoefler G, Lehner R. Tumor-induced hyperlipidemia contributes to tumor growth. Cell Rep. 2016; 15:1-13 doi: 10.1016/j.celrep.2016.03.020

Schittmayer M*, Fritz K*, Liesinger L, Griss J, Birner-Gruenberger R. Cleaning out the litterbox of proteomic scientists´ favorite pet: optimized data analysis avoiding trypsin artifacts. J Proteome Res. 2016; 15(4):1222-9 doi: 10.1021/acs.jproteome.5b01105 (*equal contribution)

Schwarzl M, Alogna A, Zweiker D, Verderber J, Huber S, Manninger M, Scherr D, Antoons G, Pieske BM, Post H, Lueger A. A porcine model of early atrial fibrillation using a custom-built, radio transmission-controlled pacemaker. J Electrocardiol. 2016; 49(2):124-31 doi: 10.1016/j.jelectrocard.2015.12.012

Koyani CN, Kitz K, Rossmann C, Bernhart E, Huber E, Trummer C, Windischhofer W, Sattler W, Malle E. Activation of the MAPK/Akt/Nrf2-Egr1/HO-1-GCLc axis protects MG-63 osteosarcoma cells against 15d-PGJ2-mediated cell death. Biochem Pharmacol. 2016; 104:29-41 doi: 10.1016/j.bcp.2016.01.011

Eroglu E, Gottschalk B,Charoensin S, Blass S, Bischof H, Rost R, Madreiter-Sokolowski CT, Pelmann B, Bernhart E, Sattler W, Hallström S, Malinski T, Waldeck-Weiermair M, Graier WF, Malli R. Development of novel FP-based probes for live-cell imaging of nitric oxide dynamics. Nat Commun. 2016; 7:10623 doi: 10.1038/ncomms10623

Alfakry H, Malle E, Koyani CN, Pussinen PJ, Sorsa T. Neutrophil proteolytic activation cascades: a possible mechanistic link between chronic periodontitis and coronary heart disease. Innate Immun. 2016; 22(1):85-99 doi: 10.1177/1753425915617521

Vujic N, Schlager S, Eichmann TO, Madreiter-Sokolowski CT, Goeritzer M, Rainer S, Schauer S, Rosenberger A, Woelfler A, Doddapattar P, Zimmermann R, Hoefler G, Lass A, Graier WF, Radovic B, Kratky D. Monoglyceride lipase deficiency modulates endocannabinoid signaling and improves plaque stability in ApoE-knockout mice. Atherosclerosis. 2016; 244:9-21 doi: 10.1016/j.atherosclerosis.2015.10.109

Drosatos K, Pollak NM, Pol CJ, Ntziachristos P, Willecke F, Valenti MC, Trent CM, Hu Y, Guo S, Aifantis I, Goldberg IJ. Cardiac myocyte KLF5 regulates Ppara expression and cardiac function. Circ Res. 2016; 118(2):241-53 doi: 10.1161/CIRCRESAHA.115.306383

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