Ulrich Stelzl



Projects within the DK-MCD

Dynamics of subcellular partitioning through protein modification – DYNIMO
Sarah Masser

Research interest

The group is focusing on the analysis of molecular interaction networks with the aim to understand the dynamics of molecular networks underlying cellular processes related to human disease. Experimental functional genomics techniques, e.g. HTP Y2H screening, are utilized in combination with biochemical, cell biological and computational methods. The current focus of our work is on the systematic analyses of the functional impact of genetic variation (population and disease variation e.g. in cancer genomes) and post-translational protein modification (phosphorylation, methylation) on protein-protein interaction, which as universal protein function underlies cellular phenotypes. Using deep scanning mutagenesis approaches, we bridge the knowledge gap between nucleotide resolution genomics and protein resolution proteomics. Network biology offers a more comprehensive understanding of biology concomitantly improving the practice of medicine.


Curriculum vitae

  1990 - 1996 Studies of Technical Chemistry/Biochemistry, Technical University of Vienna, Austria
  1994 - 1995 Studies of Biochemistry at the ETH Zurich, Switzerland
  1996 - 1999 PhD thesis, Max-Planck Institute Molecular Genetics, Berlin, Germany
  2000 Postdoctoral fellow in the working group "Ribosomes", Max Planck Institute for Molecular Genetics (MPIMG), Berlin, Germany
  2001 - 2002 Research Fellow, Memorial Sloan Kettering Cancer Center, New York, USA
  2002 - 2007 Postdoctoral fellow, NGFN project leader in the working group "Neuroproteomics", Max-Delbrück Center for Molecular Medicine (MDC), Berlin-Buch, Germany
  2007 - 2015 Max-Planck Research Group Leader, Max-Planck Institute for Molecular Genetics (MPIMG), Berlin, Germany
Head of the Otto Warburg Laboratory “Molecular Interaction Networks”
  2008 Erwin Schrödinger Award by the Hermann von Helmholtz Association of German Research Centres
  2013 - 2015 University Lecturer, Technical University Berlin (Biotechnology), Germany
  2015 - Professor at the Institute of Pharmaceutical Sciences, Department of Pharmaceutical Chemistry, University of Graz, Austria
  2016 - Faculty, BioTechMed-Graz, Austria
  2018 - Department Head, Pharmaceutical Chemistry, University of Graz, Austria


Univ.-Prof. Dipl.-Ing. Dr.rer.nat. Ulrich Stelzl

Institute of Pharmaceutical Sciences
Pharmaceutical Chemistry
University of Graz
Universitätsplatz 1/I
8010 Graz, Austria

tel.: +43 (0)316 380 5397