MUG UG TUG

Dagmar Kratky

Univ.-Prof. Mag. Dr.rer.nat. Dagmar Kratky

Institute of Molecular Biology and Biochemistry
Medical University of Graz
Neue Stiftingtalstrasse 6/6
A-8010 Graz

tel.: +43 (0)316 385 71965
e-mail: dagmar.kratky@medunigraz.at
web

 

Projects within the DK-MCD

Consequences of tissue-specific lysosomal acid lipase deficiency on lipid and carbohydrate metabolism Madalina-Cristina Duta-Mare

Role of CGI-58 in macrophage function and atherosclerosis development

Madeleine Goeritzer
graduated

Consequences of defective lipolysis in the small intestine on lipid metabolism

Melanie Korbelius

Consequences of lysosomal acid lipase deficiency on lipid and carbohydrate metabolism

Christina Leopold

Link between triacylglycerol synthesizing enzymes and cholesterol metabolism

Vinay Sachdev
graduated

Role of lipases in leukocytes

Stefanie Schlager
graduated

Monoglyceride lipase (MGL) and its role in macrophage lipid metabolism and atherosclerosis

Nemanja Vujić
graduated
   

Research interest

Intracellular lipid droplet formation, neutral lipid hydrolysis, and lipid catabolism are tightly regulated processes, which involve intracellular hydrolases, enzymes involved in lipid biosynthesis and regulatory proteins. Excessive lipid storage in lipid droplets is central to the pathogenesis of prevalent metabolic diseases, such as obesity, diabetes, fatty liver disease, and atherosclerosis.

The research interest of my group focuses on lipid metabolism and lipotoxicity in cells and tissues. We generate and utilize transgenic and knockout mouse models with varying lipid content in different cells and tissues to characterize whole-body and cell-autonomous lipid and energy metabolism, cell and tissue morphology and (dys)function. We investigate the regulation of lipid and energy metabolism with special emphasis on the role of lipolytic and lipid synthesizing enzymes and we study atherosclerosis susceptibility of the respective mouse models.

filipin moma en_face

 

Curriculum vitae

  1987 - 1997 Graduate Studies in Chemistry, University of Graz
  1995 - 1997 Master Thesis at the Institute of Biochemistry, University of Graz
  1997 Research Assistant at the Institute of Biochemistry, University of Graz
  1997 - 2000 PhD Thesis at the Institute of Molecular Biosciences, University of Graz
  2001 Research Assistant at the Institute of Pathology, University of Graz
  2002 - 2006 Assistant Professor at the Institute of Molecular Biology and Biochemistry, Medical University of Graz
  2006 Habilitation in Molecular Biology and Biochemistry, Institute of Molecular Biology and Biochemistry, Medical University of Graz
  2006 - 2012 Associate Professor at the Institute of Molecular Biology and Biochemistry, Medical University of Graz
  2010 - Deputy Head of the Institute of Molecular Biology and Biochemistry, Medical University of Graz
  2012 - Full Professor for Biochemistry at the Medical University of Graz
     

Publications

Grants