TRP ion channels regulate the transport of calcium and sodium into cells and are therefore essential for many physiological processes. However, mutations in these channels can lead to a wide range of diseases – from pulmonary hypertension and heart disease to disorders of brain development.
This doctoral program takes an innovative approach: using light-controlled molecules, advanced biosensors, and computational models, researchers investigate how disfunctional cellular signaling arises and develops into complex diseases. The interdisciplinary program at the Medical University of Graz employs state-of-the-art methods to gain fundamental insights into disease mechanisms in the lung, heart, and brain.
