PI: Gernot Grabner
Focus: We investigate how alterations in lipid metabolism affect physiological processes and disease development. We are working on lipid-degrading enzymes (lipases) particularly in inflammatory and degenerative diseases of the central nervous system. Our interdisciplinary approach includes biochemical methods, molecular biology techniques, histological-, lipid-, and behavioral analyses. We also develop chemical tools to specifically modulate the activity of lipases and advance innovative therapeutic approaches.
Network: We collaborate closely with researchers from the Medical University of Graz (Dagmar Kratky, Dagmar Kolb, Gerd Leitinger, Aitak Farzi) as well as Robert Zimmermann (Uni Graz), Rolf Breinbauer (TU Graz), Chun-Xia Yi (UMC Amsterdam), Ruth Birner-Grünberger (TU Wien), Michael Trauner (MedUni Wien), and Mario van der Stelt (Uni Leiden).
