autoimmune disease, allergies, immune tolerance, immunosenescence and cancer. Furthermore, we investigate the role of exogenous dietary factors in disease processes. Dietary factors interact with the gut [...] immune system develop from hematopoietic stem cells throughout an individual's lifetime. The investigation of long-lived lymphocytes and aspects of hematopoiesis provides insight into tissue regeneration
content of albumin. In addition the latter serves as a prognostic marker in severe liver disease. We investigate the binding properties of albumin in relation to its structure and molecular flexibility as well [...] patients with fatty liver and a possible relation to an infection with Heliobacter pylori will be investigated in this project. Duration: 2021-2022 Funded by: Med Uni Graz, BMBWF Project partner: Aleksandra [...] of albumin mainly from liver patients but also of in vitro modified albumin preparations are investigated. Duration: ongoing Funded by: Med Uni Graz Project partners: Rudolf Stauber, Med Uni Graz, Kerstin
to peroxisomal dysfunction in the absence of functional ABHD5/CGI-58 is poorly understood. PP13 investigates the consequences of ABHD5 deficiency on peroxisomal β-oxidation of fatty acids and the generation [...] skin of mice and human epidermal equivalents with keratinocytes deficient in ABHD5. Principal Investigator Priv.-Doz. Mag. Dr.rer.nat Franz Radner T: +43 316 380 1921 E: franz.radner@uni-graz.at Researchportal
calcium homeostasis under physiological and pathophysiological conditions. Thereby, the group investigates the mechanism of mitochondrial calcium homeostasis and its impact on mitochondrial function in [...] Mitochondria as potential targets in cancer and cell aging therapy The project is devoted to investigating the function and homeostasis of mitochondria in cancer and aging. Thereby, super-resolution microscopy [...] interaction of mitochondria and the endoplasmic reticulum. Besides, different cell types are used to investigate the impact of mitochondrial calcium homeostasis on metabolic activity and ROS homeostasis. Duration:
Circulation and vascular research One of the four main research areas at the Otto Loewi Research Center investigates the healthy and diseased cardiovascular system. Even though it is a vital system, it is not s [...] affected by space travel and the lack of gravity associated with it, which is another topic of investigation. By deepening our understanding of the cardiovascular system and the factors that influence it
are investigating which mechanisms underlie this health-promoting effect and which preventive and therapeutic measures can be derived from this effect for future use. Researchers will investigate naturally [...] becoming more apparent. The "Role of Comorbidities in Chronic Heart Failure" (RoC-HF) study is an investigator-initiated, prospective cohort study of more than 200 patients who received optimal therapy for
are relevant for digestion, brain function and pathological behavioural changes. In addition, we investigate the influence of genetic and environmental factors on behaviour and neurobiology to uncover novel [...] Cluster of Excellence “MetAGE”, an interdisciplinary team of basic researchers and clinicians is investigating how disturbances in metabolic control increase the risk of age-related diseases. Our team specifically [...] modulation of microbiota-gut-brain axis signalling: effects of environmental enrichment This project investigates how positive, stress resilience-promoting environmental interventions influence the microbiot
rt therapeutic options. Oncology research encompasses basic research projects, translational investigations, clinical trials and research in the field of cancer diagnostics. Main research areas To consolidate [...] Psycho-oncology Clinical trials Our division regularly tests new medical procedures in clinical investigations. By participating in clinical trials, our patients have the privilege of receiving the latest
on scientific investigation of an Osteogrow factor to improve posterolateral interbody fusion in degenerative disc disease. Labs In a specially established research lab, staff investigate bone tumors,
relevant vascular diseases. Principal Investigator Andreas Reinisch T: +43 316 385 30163 E: a.reinisch@medunigraz.at Research profile Co-Principal Investigator Dagmar Kratky T: +43 316 385 71965 E: dagmar
