catecholamines, opioids and hypnotic agents. The main element under investigation is an experimental test setup that permits investigation of the direct effect of different drugs on peristalsis. [...] . In close cooperation with the Division of Pharmacology , our working group is dedicated to investigating the influence of drugs on the peristaltic activity of the small and large intestines. Contact
detailed investigation of established drugs in order to expand their potential applications and reduce adverse effects. Inflammation, autoimmunity and cancer Our young international team investigates the role [...] include metabolism, the digestive tract, the central nervous system and the respiratory tract. We investigate manifestations of inflammatory and oncological disease with the goal of better understanding the [...] tumor-promoting immune cells (macrophages). In translational and multidisciplinary projects, we investigate the complex metabolic adaptations that may play a role in the hostile, nutrient-poor microenvironment
therapeutic and preventative strategies as well as advances in precision medicine. Metabolism Investigation of biophysics, biochemistry, molecular and cell biology of ion channels. The focus is on cancer [...] neurodegenerative disease. Research team of Wolfgang Schreibmayer & Brigitte Pelzmann Signaling Investigation of structure-function relationships in ion channels, their optogenetic and optoelectronic manipulation [...] manipulation and their role in the etiology of disease. Research team of Klaus Groschner Investigation of ion channel function and its role in signal transduction and gene regulation. Special attention is
relevant human biomaterials. Principal Investigator Kathrin Eller T: +43 316 385 12170 E: kathrin.eller@medunigraz.at Research profile Co-Principal Investigator Mahmoud Abdellatif E: mahmoud.abdellati [...] hypertension are key signs of aging, often linked to renal dysfunction. In this project, we will investigate how quality control mechanisms are impaired in various vascular cell types and in relevant models
grounds for fundamental insights on molecular time and length scales. Principal Investigators Associated Principal Investigators
age-related cardiac disorders. Principal Investigator Simon Sedej T: +43 316 385 72742 E: simon.sedej@medunigraz.at Research profile Co-Principal Investigator Mahmoud Abdellatif E: mahmoud.abdellatif@ [...] a prevalent cause of morbidity and mortality in our aging societies. In this project, we will investigate the signals and mechanisms governing age-dependent interactions between cardiomyocytes and their
in forensic medicine In some cases, sperm analysis can be used for forensic investigations. In this project we are investigating to what extent individual sperm can be used for the identification of suspects [...] autoimmune diseases, pregnancy disorders, tissue regeneration. Thus, our current projects focus on investigating how the microchimeric cells can transmigrate into the other body and in which tissues/ organs [...] Evolution Project The origin and function of microchimerism are still not clear. In this project we investigate two possible ways maternal cells might transmigrate into the child, where these cells end up and
blood vessels), intensification and promotion of the investigation of 3D cell cultures Research team of Dagmar Brislinger Microchimerism: Investigations on how microchimeric cells transmigrate into foreign [...] their target tissue. Research team of Thomas Kroneis Metabolism Liver cancer, fasting and p53: Investigation of transcriptional regulation during fasting in healthy and pathological cells and tissues Research [...] Signaling Structure and function of neuronal circuits: Use of the latest electron microscope methods Investigation of iron storage in the brain and creation of three-dimensional models of neuronal circuits Research
gical changes in movement disorders Investigation of the molecular biology and genetic basis of psychiatric disorders, especially affective disorders Investigation of endocrine, immunological and neurogenic [...] as therapy following traumatic brain injury Investigation of diet, the gut-brain axis and genetics in psychological and psychosomatic disorders Investigation of neural circuits using 3D electron microscopy
e von Heiko Bugger an der Klinischen Abteilung für Kardiologie der Med Uni Graz hat den Young Investigator Award 2022 der Society for Heart & Vascular Metabolism gewonnen. Die junge Forscherin wurde für [...] Arbeiten zur Aufklärung der ursächlichen Mechanismen der Herzinsuffizienz ausgezeichnet. Der Young Investigator Award wurde Nikole Byrne beim jährlichen Kongress der Gesellschaft verliehen, der dieses Jahr
