Research

The Medical University of Graz is devoted to excellent and internationally competitive research. The knowledge generated at Med Uni Graz benefits society in the form of concrete applications, new technologies, products, (medical or digital) services and spin-offs.

In this way, we assume social responsibility in line with our third mission. Beyond science and research, we aim to make an impact on society and the economy and facilitate the funding of pioneering projects.

Medical progress in a variety of research areas

SFB Lipidhydrolyse

Lipid and energy metabolism

Obesity, type 2 diabetes, nonalcoholic fatty liver disease and cancer are common diseases that represent a great challenge to the health care system. The special research area "Lipid Hydrolysis" funded by the Austrian Science Fund (FWF) is pursuing the long-term goal of discovering the role lipid hydrolases play in the development of disease in order to develop new treatment strategies.

It is a great challenge to identify all lipid hydrolases and describe their functions. A comprehensive understanding of the structure, function and physiological significance of this enzyme is essential in order to detect new connections between lipid and energy metabolism and the development of metabolic diseases.

Plazentaforschung

A center for placenta research

Many pregnancy complications can be attributed to a disturbance in placenta function. The doctoral program and research project "Inflammatory Disorders in Pregnancy," or DP-iDP for short, investigates the interaction between pregnancy, inflammation and the placenta in diseases affecting the mother and the fetus.

New translational methods are applied and basic researchers and clinicians work in close cooperation. Primarily diseases such as diabetes, obesity, preclampsia or intrauterine growth restriction arise along with multifactorial inflammatory diseases of the placenta. Since the exact backgrounds and mechanisms are largely unknown, they make up the research focus of this program.

CD-Labor

Non-invasive early cancer detection

Liquid biopsy is used in a variety of ways in cancer treatment and is applied to continually monitor the progress of therapy. Employing a blood test instead of tissue biopsies, it is also seen as a very promising approach for early detection of cancer. A Christian Doppler laboratory funded by the Federal Ministry of Digital and Economic Affairs has been set up with company partner Freenome Holdings.

Before liquid biopsy can be broadly used outside of clinical trials and research projects, the sensitivity and accuracy as well as the predictive and prognostic value of ctDNA must be evaluated in large prospective studies.

LBI Lungengefäßforschung

Pulmonary vascular research

Pulmonary hypertension is an insidious disease with a high number of unreported cases since there are no typical signs of the disease and the symptoms are non-specific and multiple. A diagnosis is very complex. The Ludwig Boltzmann Institute for Lung Vascular Disease strives to make an early diagnosis possible through simpler and gentler procedures and to set new standards with non-invasive procedures (if possible) and development of targeted drugs in order to improve the performance and quality of life of those who are affected.

The research focus is on the molecular mechanisms of vascular remodeling leading to the development of disease, the development of bespoke therapies and the early detection and therapy of the disease.

CBmed

Biomarker research

Biomarkers are units that can be measured biologically such as enzymes, hormones and genes that make early detection and individual therapy of diseases possible. Completely new types of biomarkers also allow entirely new treatments—and that is what the CBmed competence center is researching. These findings are implemented into practical applications in cooperation with national and international companies.

The vision of CBmed is to become the world's most recognized center for biomarker research in personalized medicine by 2030. It will achieve this by integrating cutting-edge technologies with international and interdisciplinary expertise in the fields of cancer and cardiometabolic health.

CAmed

Implants that fit perfectly

3D printing makes it possible to produce an exact component from digital models in no time at all. When adapted to meet the requirements of the highly sensitive field of medicine, these innovative technologies also have a distinct advantage. It will be possible to "print" models of the body to help surgeons prepare for an operation, implants or prostheses for direct patient use or perfectly adapted tools for individual applications.

As part of the COMET-K project "CAMed" (Clinical Additive Manufacturing for Medical Applications), an interdisciplinary research consortium of 20 international partners from science and industry are rising up to meet precisely these challenges.

Innodia

International diabetes network

According to current estimates, around ten percent of the world's population is affected by diabetes. In type 1 diabetes mellitus, the pancreas cannot supply the body with any or enough of the insulin it requires. 17 million people around the world suffer from this type of diabetes. The international research network INNODIA has set the goal of developing and expanding the search for therapeutic options that prevent and cure type 1 diabetes.

Med Uni Graz significantly contributes to the success of the project by providing its expertise: Current developments such as the artificial pancreas or the GlucoTab app for diabetes management are proof of the innovative power of Graz metabolism experts.

Diamonds

Quick detection of diseases

Symptoms such as high fever and a strong feeling of malaise can be signs of a large number of dangerous inflammatory and infectious diseases. A range of blood tests, biopsies, MRT and CT scans and other tests are often required to diagnose a disease. The development of a quick blood test to diagnose severe inflammatory and infectious diseases is the goal of scientists in the research project "DIAMONDS."

The new test may shorten the time required to detect serious diseases such as pneumonia, tuberculosis, sepsis, meningitis and autoimmune diseases to two hours.

Instand-NGS4P

Insight into DNA

DNA sequencing has caused a revolution in the biological sciences. It is no longer possible to imagine molecular biology and genetic engineering lab work without it. For example, DNA sequencing facilitates the investigation of genetic disorders. Next generation sequencing—NGS for short—is a state-of-the-art procedure for DNA sequencing that permits accelerated and cost-effective DNA sequencing through massively parallel processing.

The focus of the EU project "Instand-NGS4P" is on developing gene sequencing for more efficient use in cancer diagnostics for patients.

NanoPAT

Production of nanoparticles

Nanoparticles are atoms or molecules that are brought together to form combinations. The size of this particle ranges from 1 to 100 nanometers (1 Nanometer = 1 billionth of a meter). We encounter nanoparticles every day in a wide variety of products for daily use. For example, they are found in cosmetic products, coatings, infusions, food supplements and much more. They are thousands of times smaller than the diameter of a human hair.

In the EU project "NanoPAT," scientists are concerned with how to improve quality and efficiency in the production of nanoparticles. Med Uni Graz researchers contribute their expertise in process analytical technologies to the consortium.

An innovative research environment at a glance

MED CAMPUS Graz

MED CAMPUS Graz

MED CAMPUS Graz is a place where the clinical and non-clinical areas of the Medical University of Graz are brought together. This is where Med Uni Graz creates profiles and emphases in teaching, research and patient care and makes optimal use of resources and synergies.

Forschungszentren & Institute

Research Centers and Institutes

Teaching, research and diagnostics are carried out according to the biopsychosocial model in three basic research centers and four unaffiliated institutes. This pooling of strengths into the research centers makes the dimension and content of research potential visible both inside and outside.

Universitätskliniken

University Departments

At 19 university departments, our University Hospital Graz staff provide first-class and personalized patient care, receive innovative and practice-oriented education and conduct forward-looking and excellent research. The departments are led by professors in the respective specialist fields who are employed by the Medical University of Graz.

Universitätsbibliothek

University Library

University Library is a public library that is open to all. Readers have a choice of 180 seats where they can study and work. 52 fully equipped IT workspaces provide the most modern infrastructure for our visitors. The books, journals and electronic resources may be used within the library without any restrictions.

Biobank

Biobank Graz

Biobank Graz houses a collection of human biological specimens and associated data that is well structured and ready to be analyzed. With around 20 million biological specimens, it is one of the largest clinical biobanks in Europe. The goal of Biobank Graz is to improve health care for the population.

Biomedizinische Forschung

Biomedical Research (BMF)

Biomedical Research is responsible for caring for laboratory animals at different hygiene levels and provides research projects with special infrastructure and special lab areas. Given the strict legal and ethical requirements for animal experimentation, Biomedical Research supports researchers in planning and executing tests as well as evaluating existing methods and developing new alternative methods (3R).

ZMF

Center for Medical Research (ZMF)

The Center for Medical Research provides first-class infrastructure for point-of-care research. Specially constructed to meet the requirements of biomedical research, the modern building is located in the center of University Hospital Graz and in direct proximity to MED CAMPUS Graz. More than 4,000 square meters of well-equipped laboratories and offices as well as excellent core facilities are available for services.

Zentrum für Wissenstransfer

Center for Knowledge and Technology Transfer (ZWT)

The Center for Knowledge and Technology Transfer in Medicine is directly connected to MED CAMPUS and University Hospital Graz. As co-owner of the center, the Styrian Business Promotion Agency (SFG) supports close networking with the industry. Research space is available at the center for innovative companies in the area of life sciences.

Special research infrastructure at Med Uni Graz

Hochsicherheitslabor

High security lab

MED CAMPUS Graz has a biosafety level 3 (BSL-3) lab at the Diagnostic and Research Institute of Pathology. This lab infrastructure is unique in Austria. Camera surveillance, entry checks, protective clothing and chemical showers allow work with highly infectious dangerous microorganisms that can cause serious disease and epidemics. This year the demand to use the lab for research and development projects as well as cooperations in COVID-19 research was especially great.

Zentrum für Integrative Stoffwechselforschung

Integrative Metabolic Research Center

The Integrative Metabolic Research Center established at MED CAMPUS Graz is a project financed by Higher Education Area Structural Funds program of the Austrian Federal Ministry of Education, Science and Research as part of the BioTechMed-Graz cooperation. Research at the center focuses on exploring the molecular mechanisms behind the development of disease and their connection to environmental influences, aging and stress using metabolites.

Transmissionselektronenmikroskop

Transmission electron microscope

The transmission electron microscope for analyzing tissue sections and protein samples is another part of the research infrastructure financed by the Higher Education Area Structural Funds program of the Austrian Federal Ministry of Education, Science and Research. This technology is applied to look into the center of cells, tissue and tumors. Three-dimensional electron microscopy allows new insights into different cell organelles, visualizing functional relationships in terms of ultrastructures and thereby making comprehensible the possibilities for medical intervention, for example in tumor biology.

Nikon-Center of Excellence

NIKON Center of Excellence

The NIKON Center of Excellence for Super-resolution Microscopy: Cells and Organelles supplies Graz researchers with a unique microscope that represents a breakthrough in resolution and measuring speed and provides another clear impetus in the field of biomedical research at science hub Graz. The center not only permits state-of-the-art microscopy but also provides a platform for the free exchange of ideas, methods and technologies between scientists and NIKON. The joint promotion of research and the development of new technologies are the declared goals of both parties.

Contact

Vice Rector of Research and International Affairs 
T: +43 316 385 72012