PI: Dagmar Brislinger
Focus: The importance of two-dimensional cell culture is non-controversial. Biochemical pathways and effects of treatments in single cell types can be identified in standardized processes. Nevertheless, the gap between a two-dimensional cell culture experiment and a complete organism is difficult to bridge, thus results can hardly be related. Although tissue and organ culture pose a challenge to the experimental design investigations will represent the in vivo situation closer than conventional two-dimensional cell culture. We therefore intensify and promote research on the establishment of three-dimensional cell cultures.
Network: The research group have established intense cooperation with researchers of the Gottfried Schatz Research Center for Cell Signaling, Metabolism and Aging and various institutes and divisions (e.g. Division of Transplantation Surgery, Division of Anaesthesiology for Cardiovascular Surgery and Intensive Care Medicine, Diagnostics & Research Institute of Pathology). Further, the research group has a long-lasting cooperation with the Institute of Multiphase Processes, Leibniz University Hannover, Germany.
