PI: Magdalena Grill
Focus: Our research group is dedicated to understanding the complex interplay between inflammation, tissue repair, and disease progression. A temporary alteration in cell phenotype is a natural response to injury and inflammatory stimuli, often leading to the resolution of inflammation and tissue repair. However, when these changes become persistent, they can disrupt tissue integrity and function, contributing to chronic inflammation, disease progression and even tumor development. We aim to identify and characterize inflammation associated, long lasting changes in tissue-resident, non-hämatopoietic cells, with a particular focus on fibroblasts, endothelial cells, and astrocytes.
Network: We collaborate with various groups internally at the Medical University of Graz, as well as nationally and internationally. The Division of Phoniatrics, University Department for Ear, Nose and Throat Medicine, and the Diagnostic and Research Institute for Human Genetics, both Med Uni Graz, are involved in current projects. We also maintain contact and exchange information with the Division of Pharmacology, Med Uni Graz, the Diagnostic and Research Institute for Pathology, Med Uni Graz, the Department of Neurology, Med Uni Vienna, the Institute for Pathophysiology and Allergy Research, Med Uni Vienna, and the School of Life and Environmental Sciences, University of Sydney, Australia.