PI: Stefano Angiari
Focus: Using a multidisciplinary approach (in vitro primary T cell cultures, biochemical assays, protein and gene expression analysis and in vivo disease models), we explore the complex role of T cells in inflammation and autoimmunity. We study all aspects of T cell biology, with a particular focus on the metabolic regulation of T cell responses. In addition, our main goal is to translate our results into questions relevant to human medicine, and to investigate how T cells influence the induction, development and severity of inflammatory and autoimmune diseases in humans.
Network: We are currently cooperating with international research partners from Ireland and Italy. In parallel, we are establishing new collaborations with clinicians and researchers at the Medical University of Graz.